Axid Pulvules Side Effects

Generic name: nizatidine

Medically reviewed by Drugs.com. Last updated on Dec 4, 2024.

Note: This document provides detailed information about Axid Pulvules Side Effects associated with nizatidine. Some dosage forms listed on this page may not apply specifically to the brand name Axid Pulvules.

Applies to nizatidine: oral capsule, oral tablet.

Precautions

It is very important that your doctor check your or your child's progress at regular visits to make sure this medicine is working properly. Blood and urine tests may be needed to check for unwanted effects.

If your condition does not improve, or if it become worse, check with your doctor.

Before you have any medical tests, tell the medical doctor in charge that you are taking this medicine. The results of some tests may be affected by this medicine.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of Axid Pulvules

Along with its needed effects, nizatidine (the active ingredient contained in Axid Pulvules) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking nizatidine:

Other side effects of Axid Pulvules

Some side effects of nizatidine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

See also:

For healthcare professionals

Applies to nizatidine: oral capsule, oral solution, oral tablet.

General adverse events

The most commonly reported side effects included headache, rhinitis, abdominal pain, and diarrhea.^[Ref]

Nervous system

• Very common (10% or more): Headache (up to 16.6%)
• Common (1% to 10%): Dizziness, somnolence
• Frequency not reported: Seizure^[Ref]

A pediatric patient given 2.5 mg/kg orally 2 times a day for 23 days experienced an EEG-diagnosed seizure during treatment.^[Ref]

Gastrointestinal

• Common (1% to 10%): Constipation, diarrhea, dry mouth, dyspepsia, flatulence, gastrointestinal disorder, nausea, nausea and vomiting, tooth disorder, vomiting^[Ref]

Respiratory

• Common (1% to 10%): Cough, cough increased, nasal congestion, nasopharyngitis, pharyngitis, rhinitis, sinusitis
• Postmarketing reports: Bronchospasm, laryngeal edema^[Ref]

Other

• Common (1% to 10%): Accident, asthenia, fever, injury, pain, pyrexia, surgical procedure^[Ref]

Psychiatric

• Common (1% to 10%): Abnormal dreams, anxiety, insomnia, irritability, nervousness
• Postmarketing reports: Decreased libido, reversible mental confusion^[Ref]

Dermatologic

• Common (1% to 10%): Pruritus, rash, sweating, urticaria
• Postmarketing reports: Exfoliative dermatitis^[Ref]

Musculoskeletal

• Common (1% to 10%): Back pain, myalgia
• Postmarketing reports: Arthralgia^[Ref]

Immunologic

• Common (1% to 10%): Infection
• Rare (0.01% to 0.1%): Serum sickness, serum sickness-like reactions^[Ref]

Cardiovascular

• Common (1% to 10%): Chest pain
• Frequency not reported: Short episodes of asymptomatic ventricular tachycardia
• Postmarketing reports: Vasculitis^[Ref]

Metabolic

• Common (1% to 10%): Anorexia
• Postmarketing reports: Hyperuricemia unrelated to gout or nephrolithiasis^[Ref]

Ocular

• Common (1% to 10%): Amblyopia^[Ref]

Hematologic

• Uncommon (0.1% to 1%): Anemia
• Postmarketing reports: Agranulocytosis, eosinophilia, fatal thrombocytopenia, leukopenia, thrombocytopenic purpura^[Ref]

Fatal thrombocytopenia was reported in a patient who experienced possible drug-related thrombocytopenia previously received this drug and another histamine-2 (H2) receptor antagonist.^[Ref]

Hepatic

• Rare (0.01% to 0.1%): Transient, marked transaminase elevations, transient, marked alkaline phosphatase elevations
• Frequency not reported: Elevated liver enzyme tests (alkaline phosphatase, ALT, AST), hepatocellular injury, transient, asymptomatic transaminase elevations, transient, asymptomatic alkaline phosphatase elevations
• Postmarketing reports: Cholestatic injury, cholestatic injury with jaundice, hepatitis, jaundice, mixed hepatocellular injury, mixed hepatocellular injury with jaundice^[Ref]

Some patients developed ALT and/or AST elevations exceeding 500 international units/L, with a report of an ALT level exceeding 2000 international units/L.

Some patients 2 to 18 years developed mild elevations in serum transaminase levels (1 to 2 times the upper limit of normal).

Liver enzyme elevations and liver abnormalities were reversible upon discontinuation of treatment.^[Ref]

Hypersensitivity

• Postmarketing reports: Anaphylaxis, hypersensitivity reactions^[Ref]

Hypersensitivity reactions included bronchospasm, eosinophilia, laryngeal edema, and rash.^[Ref]

Genitourinary

• Postmarketing reports: Impotence^[Ref]

Endocrine

• Postmarketing reports: Gynecomastia^[Ref]

Further information

Axid Pulvules side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

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