Aclidinium Side Effects

Medically reviewed by Drugs.com. Last updated on Sep 5, 2024.

Applies to aclidinium: inhalation aerosol powder.

Precautions

It is very important that your doctor check your progress closely while you are using this medicine to see if it is working properly and to check for any unwanted effects.

Tell your doctor about other medicines you are using for COPD. Follow your doctor's instructions on how you should take your medicine.

This medicine should not be used if you are having a COPD attack, or if symptoms of a COPD attack has already started. Your doctor will prescribe another medicine for you to use in case of an acute attack. If the other medicine does not work as well, tell your doctor right away.

Talk with your doctor or get medical care right away if:

• Your symptoms do not improve after using this medicine or if they become worse.
• Your short-acting inhaler (rescue medicine) does not seem to work as well as it used to and you need it more often than normal.

This medicine should not be used together with similar medicines, such as atropine (Atropen®), ipratropium (Atrovent, Apovent®, Ipraxa®, Rinatec®), glycopyrrolate (Robinul®), tiotropium (Spiriva®, Braltus®), or umeclidinium (Incruse™ Ellipta®).

This medicine may cause paradoxical bronchospasm, which means your breathing or wheezing will get worse. Paradoxical bronchospasm may be life-threatening. Check with your doctor right away if you have coughing, difficulty breathing, shortness of breath, or wheezing after using this medicine.

Check with your doctor right away if you have any changes to your vision, such as eye pain or discomfort, blurred vision, visual halos, or colored images with red eyes while you are using this medicine. Your doctor may want your eyes be checked by an eye doctor (ophthalmologist). These could be symptoms of acute narrow-angle glaucoma.

This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. Call your doctor right away if you have a rash, itching, trouble breathing, trouble swallowing, or any swelling of your hands, face, mouth, or throat while you are using this medicine.

Check with your doctor right away if you have decrease in urine volume, decrease in the frequency of urination, difficulty in passing urine, or painful urination.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines for appetite control, asthma, colds, cough, hay fever, or sinus problems, and herbal or vitamin supplements.

Serious side effects of aclidinium

Along with its needed effects, aclidinium may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aclidinium:

Other side effects of aclidinium

Some side effects of aclidinium may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to aclidinium: inhalation powder.

Gastrointestinal adverse events

• Common (1% to 10%): Diarrhea (2.7%), toothache (1.1%), vomiting (1.1%)
• Uncommon (0.1% to 1%): Dry mouth, abdominal discomfort, tooth abscess
• Postmarketing reports: Nausea, stomatitis^[Ref]

Nervous system

• Common (1% to 10%): Headache (6.6%)
• Uncommon (0.1% to 1%): Dizziness^[Ref]

Other

• Common (1% to 10%): Fall (1.1%)
• Uncommon (0.1% to 1%): Candidiasis^[Ref]

Respiratory

• Common (1% to 10%): Nasopharyngitis (5.5%), cough (3%), sinusitis (1.7%), rhinitis (1.6%)
• Uncommon (0.1% to 1%): Dysphonia^[Ref]

Cardiovascular

• Uncommon (0.1% to 1%): First degree AV block, cardiac failure, cardiorespiratory arrest, palpitations
• Postmarketing reports: Tachycardia^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Rash, pruritus^[Ref]

Genitourinary

• Uncommon (0.1% to 1%): Urinary retention^[Ref]

Metabolic

• Uncommon (0.1% to 1%): Diabetes mellitus (less than 1%)^[Ref]

Musculoskeletal

• Uncommon (0.1% to 1%): Osteoarthritis (less than 1%)^[Ref]

Ocular

• Uncommon (0.1% to 1%): Blurred vision^[Ref]

Hypersensitivity

• Postmarketing reports: Immediate hypersensitivity reactions, including anaphylaxis, angioedema (including swelling of the lips, tongue, or throat), urticaria, rash, bronchospasm, itching^[Ref]

See also:

Further information

Aclidinium side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer