Generic Name: teriparatide (ter i PAR a tide)
Brand Name: Forteo
Medically reviewed on December 4, 2017
What is teriparatide?
Teriparatide is a man-made form of parathyroid hormone that exists naturally in the body. Teriparatide increases bone mineral density and bone strength, which may prevent fractures.
Teriparatide may also be used for purposes not listed in this medication guide.
Tell your doctor if you have conditions such as Paget's disease, high blood levels of calcium or alkaline phosphatase, or a history of bone cancer or radiation treatment involving your bones.
Avoid smoking cigarettes or drinking alcohol. Smoking or heavy drinking can reduce your bone mineral density, making fractures more likely.
Before taking this medicine
You should not use teriparatide if you are allergic to it.
Teriparatide is not for use in children or young adults whose bones are still growing.
To make sure teriparatide is safe for you, tell your doctor if you have ever had:
Paget's disease or a bone disease other than osteoporosis;
high blood levels of calcium or alkaline phosphatase;
overactive parathyroid glands;
bone cancer or radiation treatment involving your bones; or
a kidney stone.
Teriparatide has caused bone cancer (osteosarcoma) in animals but it is not known whether this would occur in people using teriparatide. Talk with your doctor about your own risk.
While using teriparatide, you may be asked to provide your name to a patient registry. This is to collect information about any possible risk of bone cancer in people who take this medicine.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
It is not known whether teriparatide passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
How should I use teriparatide?
Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.
Teriparatide is injected under the skin. You may be shown how to use injections at home. Do not give yourself this medicine if you do not understand how to use the injection and properly dispose of used needles and syringes.
Teriparatide is usually given once per day. Use the medicine at the same time each day.
Your care provider will show you the best places on your body to inject teriparatide. Use a different place each time you give an injection. Do not inject into the same place two times in a row.
Use only the injection pen provided with teriparatide. Do not transfer the medicine to a syringe or other injection device or you could get an overdose.
Teriparatide can cause you to feel dizzy or light-headed. Always give your injection at a time and place where you can sit or lie down for a short time afterward.
Each prefilled injection pen contains enough teriparatide for 28 separate injections. Throw the pen away after 28 injections, even if there is still medicine left inside.
Teriparatide should be clear and colorless. Do not use the medicine if it has changed colors, looks cloudy, or has particles in it. Call your pharmacist for new medicine.
Use a disposable needle only once. Follow any state or local laws about throwing away used needles. Use a puncture-proof "sharps" disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
Teriparatide may be only part of a complete program of treatment that also includes diet changes, exercise, taking vitamin or mineral supplements, and changing certain behaviors. Follow your doctor's instructions very closely.
Store your teriparatide injection pen in the refrigerator when not in use. Take the pen out of the refrigerator only long enough to use it. After use, remove the needle, recap the pen, and return it to the refrigerator.
Do not freeze teriparatide, and throw away the medicine if it has become frozen.
Your doctor will determine how long to treat you with this medicine. Teriparatide is often given for only 2 years.
What happens if I miss a dose?
Use the missed dose on the same day you remember it. Use your next dose at the regular time and stay on your once-daily schedule. Do not use 2 doses in one day.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while using teriparatide?
Teriparatide can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
Avoid smoking, or try to quit. Smoking can reduce your bone mineral density, making fractures more likely.
Avoid drinking large amounts of alcohol. Heavy drinking can also cause bone loss.
Teriparatide side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
a light-headed feeling, like you might pass out (may occur within 4 hours after injection);
pounding heartbeats or fluttering in your chest after using an injection; or
high levels of calcium in your blood--nausea, vomiting, constipation, muscle weakness, lack of energy, or tired feeling.
Common side effects may include:
joint pain; or
pain anywhere in your body.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Teriparatide dosing information
Usual Adult Dose for Osteoporosis:
20 mcg subcutaneously once a day into the thigh or abdominal wall
-Treatment of postmenopausal women with osteoporosis at high risk for fracture
-Increase of bone mass in men with primary or hypogonadal osteoporosis at high risk for fracture
-Treatment of men and women with osteoporosis associated with sustained systemic glucocorticoid therapy at high risk for fracture
What other drugs will affect teriparatide?
Tell your doctor about all your current medicines and any you start or stop using, especially:
This list is not complete. Other drugs may interact with teriparatide, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 2.02.
More about teriparatide
- Teriparatide Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 84 Reviews
- Drug class: parathyroid hormone and analogs
Other brands: Forteo