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I just took ibuprofen and prednisone, is that ok?

Medically reviewed by Drugs.com. Last updated on Oct 17, 2024.

Official Answer by Drugs.com

There is a moderate interaction between Ibuprofen and prednisone. It should only used together on the instruction of a Doctor, and needs to be used with caution together especially if you are prone to stomach upset including stomach ulcers and bleeding.

Both medications taken together can cause serious gastric complications in some patients.
If after taking you develop any unusual bleeding or stomach pain, dizziness or tarry stools tell your doctor immediately.

For more information on this interaction see:

https://www.drugs.com/drug-interactions/ibuprofen-with-prednisolone-1310-0-1933-0.html

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Can you take ibuprofen on an empty stomach?

Despite the common belief that you must take ibuprofen with food, you can safely take low-dose ibuprofen (up to 1200 mg daily in divided doses for 1 to 7 days) on an empty stomach, and this provides faster pain relief than taking ibuprofen with food. Food slows ibuprofen absorption time, although it doesn't affect the total amount absorbed. There is actually no scientific evidence that taking ibuprofen with food prevents stomach irritation. Over-the-counter ibuprofen doses have a low incidence of gastric problems anyway.

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Can you take expired ibuprofen?

Although taking expired ibuprofen is not recommended by the manufacturer, the actual shelf-life is likely to be longer than that indicated by the expiry date, with FDA testing showing many drugs are active for years beyond their expiry date, although specific data on ibuprofen is not available. Within reason, an ibuprofen tablet that is a few months past its expiry date is probably safe to take. Ibuprofen that is years past its expiry date should not be taken. Continue reading

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