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Can you take Xanax if you are on prednisone?

Medically reviewed by Drugs.com. Last updated on Oct 23, 2023.

Official answer

by Drugs.com

Yes, Xanax and prednisone can be taken together. There is only a minor interaction between the two. Minor interactions do not usually cause harm OR require a change in therapy. Your health care provider will determine if adjustments to your medication are needed.

Certain corticosteroids may decrease the plasma concentration of some benzodiazepines. The mechanism is related to induction of hepatic cytochrome P450 enzymes responsible for benzodiazepine metabolism. The clinical significance may depend on the dosage and duration of corticosteroid therapy and be of greater importance with oral administration of benzodiazepines.

Xanax and Prednisone Interactions Report

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What is considered a high dose of prednisone?

The starting dose of prednisone may be between 5 mg to 60 mg per day. A dose above 40 mg per day may be considered a high dose. However, everybody responds differently to prednisone, so what might be a high dose depends on the person and the condition. Continue reading

Is it OK to drink alcohol with Prednisone?

Although there is no direct drug interaction between prednisone and alcohol, mixing them together is not a good idea because some of the effects of alcohol and the side effects of prednisone are similar, so taking both at the same time can increase the risk of these side effects occurring. Continue reading

How long can you take prednisone safely?

There is no set limit on how long you can safely take prednisone. It depends on the dose of prednisone and the condition being treated. It may be prescribed short term or long term. The dosage will be adjusted or stopped based on your response or lack of response to the medication. Continue reading

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