How long does prednisone stay in your system?
Medically reviewed by Drugs.com. Last updated on Nov 2, 2023.
You could expect a dose of prednisone to stay in your system for 16.5 to 22 hours.
The elimination half life of prednisone is around 3 to 4 hours. This is the time it takes for your body to reduce the plasma levels by half. It usually takes around 5.5 half lives for a drug to be completely eliminated from your system.
Other factors that can cause variation to the elimination time include:
- How much and how often you have taken the drug.
- Your metabolic rate – a slower metabolism will increase the time a drug remains in your system.
- Your age and health – older age and poor health will generally increase the time the drug stays in your system.
- Body mass – generally the bigger you are the longer a drug will remain in your system.
For more information see: https://www.drugs.com/ppa/prednisone.html
Read next
What is considered a high dose of prednisone?
The starting dose of prednisone may be between 5 mg to 60 mg per day. A dose above 40 mg per day may be considered a high dose. However, everybody responds differently to prednisone, so what might be a high dose depends on the person and the condition. Continue reading
Is it OK to drink alcohol with Prednisone?
Although there is no direct drug interaction between prednisone and alcohol, mixing them together is not a good idea because some of the effects of alcohol and the side effects of prednisone are similar, so taking both at the same time can increase the risk of these side effects occurring. Continue reading
How long can you take prednisone safely?
There is no set limit on how long you can safely take prednisone. It depends on the dose of prednisone and the condition being treated. It may be prescribed short term or long term. The dosage will be adjusted or stopped based on your response or lack of response to the medication. Continue reading
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Drug information
- Prednisone Information for Consumers
- Prednisone prescribing info & package insert (for Health Professionals)
- Side Effects of Prednisone (detailed)
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