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Antiviral combinations

What are Antiviral combinations?

Antiviral combinations have more than one antiviral agent in the one pill or dose. Using a combination of antiviral agents reduces the risk of resistant virus strains from emerging.

Antiviral agents are used to inhibit production of viruses that cause disease. Most antiviral agents are only effective while the virus is replicating.

It is difficult to find medicines that are selective for the virus as viruses share most of the metabolic processes of the host cell. However, some enzymes are only present in viruses and these are potential targets for drugs.

Agents that inhibit the transcription of the viral genome are DNA polymerase inhibitors and reverse transcriptase inhibitors. Protease inhibitors inhibit the post-translational events. Other antiviral agents inhibit the virus from attaching to or penetrating the host cell. Immunomodulators induce production of host cell enzymes, which stop viral reproduction. Integrase strand transfer inhibitors prevent integration of the viral DNA into the host DNA by inhibiting the viral enzyme integrase. Neuraminidase inhibitors block viral enzymes and inhibit reproduction of the viruses.

List of Antiviral combinations

View by  Generic | Brand
Drug Name Avg. Rating Reviews
nirmatrelvir / ritonavir systemic (Pro)
Brand name: Paxlovid
7.2
540 reviews
glecaprevir / pibrentasvir systemic (Pro)
Brand name: Mavyret
8.4
425 reviews
sofosbuvir / velpatasvir systemic (Pro)
Brand name: Epclusa
7.8
417 reviews
ledipasvir / sofosbuvir systemic (Pro)
Brand name: Harvoni
8.6
412 reviews
bictegravir / emtricitabine / tenofovir alafenamide systemic (Pro)
Brand name: Biktarvy
7.2
221 reviews
cobicistat / elvitegravir / emtricitabine / tenofovir alafenamide systemic (Pro)
Brand name: Genvoya
7.3
129 reviews
abacavir / dolutegravir / lamivudine systemic
Brand names: Triumeq, Triumeq PD
8.3
128 reviews
efavirenz / emtricitabine / tenofovir disoproxil systemic (Pro)
9.1
110 reviews
cobicistat / elvitegravir / emtricitabine / tenofovir disoproxil systemic (Pro)
Brand name: Stribild
9.5
89 reviews
emtricitabine / rilpivirine / tenofovir disoproxil systemic
Brand name: Complera
8.3
60 reviews
elbasvir / grazoprevir systemic (Pro)
Brand name: Zepatier
8.9
53 reviews
dolutegravir / lamivudine systemic (Pro)
Brand name: Dovato
6.8
50 reviews
emtricitabine / tenofovir disoproxil systemic (Pro)
Brand names: AccessPak for HIV PEP Basic, Truvada
6.1
43 reviews
cabotegravir / rilpivirine systemic (Pro)
Brand name: Cabenuva
7.9
24 reviews
emtricitabine / tenofovir alafenamide systemic (Pro)
Brand name: Descovy
7.3
22 reviews
emtricitabine / rilpivirine / tenofovir alafenamide systemic
Brand name: Odefsey
8.4
10 reviews
cobicistat / darunavir / emtricitabine / tenofovir alafenamide systemic (Pro)
Brand name: Symtuza
8.2
9 reviews
dolutegravir / rilpivirine systemic (Pro)
Brand name: Juluca
8.1
8 reviews
abacavir / lamivudine systemic (Pro)
Brand name: Epzicom
9.6
8 reviews
doravirine / lamivudine / tenofovir disoproxil systemic (Pro)
Brand name: Delstrigo
9.6
7 reviews
lamivudine / zidovudine systemic (Pro)
5.8
4 reviews
cobicistat / darunavir systemic
Brand name: Prezcobix
4.0
3 reviews
sofosbuvir / velpatasvir / voxilaprevir systemic (Pro)
Brand name: Vosevi
10
2 reviews
abacavir / lamivudine / zidovudine systemic (Pro)
9.0
1 review
lamivudine / tenofovir disoproxil systemic
Brand names: Cimduo, Temixys
No reviews
emtricitabine / nelfinavir / tenofovir disoproxil systemic
Brand name: AccessPak for HIV PEP Expanded with Viracept
No reviews
emtricitabine / lopinavir / ritonavir / tenofovir disoproxil systemic
Brand name: AccessPak for HIV PEP Expanded with Kaletra
No reviews
efavirenz / lamivudine / tenofovir disoproxil systemic (Pro)
Brand names: Symfi, Symfi Lo
No reviews
atazanavir / cobicistat systemic
Brand name: Evotaz
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.