Medications for Pre-Exposure Prophylaxis

Other names: Pre-Exposure Prophylaxis HIV Infection; PrEP; Reducing Risk of HIV Infection

About Pre-Exposure Prophylaxis

Pre-exposure prophylaxis (PrEP) is reducing the risk of HIV infection in uninfected individuals who are at high risk.

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name	Rating	Reviews	Rx/OTC	Pregnancy	CSA
Truvada	5.8	16 reviews	Rx	B	N
Generic name: emtricitabine / tenofovir systemic Drug class: antiviral combinations For consumers: dosage, interactions, side effects For professionals: Prescribing Information

Descovy	10	2 reviews	Rx		N
Generic name: emtricitabine / tenofovir alafenamide systemic Drug class: antiviral combinations For consumers: dosage, interactions, side effects For professionals: Prescribing Information

emtricitabine / tenofovir	5.8	16 reviews	Rx	B	N
Generic name: emtricitabine / tenofovir systemic Brand names: Truvada, AccessPak for HIV PEP Basic Drug class: antiviral combinations For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts, Prescribing Information

AccessPak for HIV PEP Basic	Rate	Add review	Rx	B	N
Generic name: emtricitabine / tenofovir systemic Drug class: antiviral combinations For consumers: dosage, interactions, side effects

emtricitabine / tenofovir alafenamide	10	2 reviews	Rx		N
Generic name: emtricitabine / tenofovir alafenamide systemic Brand name: Descovy Drug class: antiviral combinations For consumers: dosage, interactions, side effects For professionals: A-Z Drug Facts

Rating	For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity	Activity is based on recent site visitor activity relative to other medications in the list.
Rx	Prescription Only.
OTC	Over the Counter.
Rx/OTC	Prescription or Over the Counter.
Off-label	This medication may not be approved by the FDA for the treatment of this condition.

Pregnancy Category
A	Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B	Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C	Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D	There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X	Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N	FDA has not classified the drug.

Controlled Substances Act (CSA) Schedule
N	Is not subject to the Controlled Substances Act.
1	Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2	Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3	Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4	Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5	Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.

Alcohol
X	Interacts with Alcohol.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.