Generic Name: dolutegravir and rilpivirine
Brand Names: Juluca
Medically reviewed on March 7, 2018.
What is Juluca?
Juluca is used to treat HIV, the virus that can cause the acquired immunodeficiency syndrome (AIDS).
Juluca is not a cure for HIV or AIDS.
Juluca is for use only in people who have been successfully treated with other antiviral medications for at least 6 months.
Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.
Before taking this medicine
You should not use Juluca if you are allergic to dolutegravir or rilpivirine.
Some medicines can cause unwanted or dangerous effects when used with Juluca. Your doctor may need to change your treatment plan if you use any of the following drugs:
dofetilide (can cause serious medical problems or death when taken with Juluca);
St John's wort;
more than one dose of dexamethasone;
Tell your doctor if you have ever had:
It is not known whether dolutegravir and rilpivirine will harm an unborn baby. Tell your doctor if you are pregnant. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Juluca on the baby.
Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
How should I take Juluca?
Take Juluca exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Always take this medicine with food, not with a meal replacement drink.
You will need frequent blood tests.
Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
Get your prescription refilled before you run out of medicine completely.
Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with any packet or canister of moisture-absorbing preservative.
Juluca dosing information
Usual Adult Dose of Juluca for HIV Infection:
1 tablet orally once a day with a meal
Use: As a complete regimen for the treatment of HIV-1 infection to replace a stable antiretroviral regimen in patients who are virologically-suppressed (HIV-1 RNA less than 50 copies/mL) for at least 6 months with no history of treatment failure and no known substitutions associated with resistance to the individual components
See also: Dosage Information (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking Juluca?
This medication will not prevent you from passing HIV to other people. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
Juluca side effects
Stop taking this medicine and get emergency medical help if you have signs of an allergic reaction to Juluca: fever, general ill feeling, trouble breathing, extreme tiredness; mouth sores, redness or swelling in your eyes; blistering or peeling skin; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
thoughts about suicide or hurting yourself;
anxiety, sadness, feeling hopeless; or
Common Juluca side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Juluca?
Some medicines can make Juluca less effective when taken at the same time. If you take any of the following medicines, take your dose at least 4 hours before or 6 hours after you take the other medicine.
buffered medicine; or
vitamin or mineral supplements that contain calcium or iron (but if you take dolutegravir and rilpivirine with food, you can take these supplements at the same time).
Many drugs can interact with dolutegravir and rilpivirine, and some drugs should not be used together. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Juluca only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 1.01.
More about Juluca (dolutegravir / rilpivirine)
- Juluca Side Effects
- During Pregnancy
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
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- Drug class: antiviral combinations