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Medications for Indigestion

The medications listed below are related to or used in the treatment of this condition.

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Drug name Rating Reviews Activity ? Rx/OTC Pregnancy CSA Alcohol
omeprazole 3.9 48 reviews for omeprazole to treat Indigestion
Rx/OTC C N
Generic name:
omeprazole systemic
Brand names:
Prilosec, Prilosec OTC
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
bismuth subsalicylate 8.1 16 reviews for bismuth subsalicylate to treat Indigestion
Rx/OTC N N
Generic name:
bismuth subsalicylate systemic
Brand names:
Pepto-Bismol, Kaopectate, Bismarex, Bismatrol, Bismatrol Maximum Strength, Kola-Pectin DS, Peptic Relief, Percy Medicine, Pink Bismuth
Drug class:
antidiarrheals
For consumers:
dosage, interactions, side effects
famotidine 4.3 14 reviews for famotidine to treat Indigestion
Rx/OTC B N
Generic name:
famotidine systemic
Brand names:
Pepcid, Pepcid AC, Acid Controller Maximum Strength, Heartburn Relief, Pepcid AC Chewable Tablets, Acid Controller Original Strength, Pepcid Oral Suspension
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Pepto-Bismol 8.5 14 reviews for Pepto-Bismol to treat Indigestion
Rx/OTC N N
Generic name:
bismuth subsalicylate systemic
Drug class:
antidiarrheals
For consumers:
dosage, interactions, side effects
calcium carbonate 7.5 11 reviews for calcium carbonate to treat Indigestion
OTC N N
Generic name:
calcium carbonate systemic
Brand names:
Tums Regular Strength, Tums Extra Strength 750, Tums Ultra 1000, Alka-Seltzer Cool Action Heartburn Relief Gum, Alka-Seltzer Heartburn ReliefChews, Cal-Gest, Cal-Mint, Calci-Chew, Calcium Oyster Shell, Icar Prenatal Chewable Calcium, Oyster Cal, Oyster Calcium, Oyster Shell, Oyster Shell Calcium 500, Titralac, Tums Antacid Naturals, Tums Chewy Bites, Tums Chewy Delights, Tums Smoothies, Tums Smoothies Extra Strength, Tums Sugar-Free
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
magnesium hydroxide 7.2 11 reviews for magnesium hydroxide to treat Indigestion
Rx/OTC N N
Generic name:
magnesium hydroxide systemic
Brand names:
Milk of Magnesia, Phillips' Milk of Magnesia, Dulcolax Milk of Magnesia, Ex-Lax Milk of Magnesia
Drug class:
antacids, laxatives
For consumers:
dosage, interactions, side effects
Milk of Magnesia 7.0 5 reviews for Milk of Magnesia to treat Indigestion
Rx/OTC N N
Generic name:
magnesium hydroxide systemic
Drug class:
antacids, laxatives
For consumers:
dosage, interactions, side effects
Phillips' Milk of Magnesia 8.2 5 reviews for Phillips' Milk of Magnesia to treat Indigestion
Rx/OTC N N
Generic name:
magnesium hydroxide systemic
Drug class:
antacids, laxatives
For consumers:
dosage, interactions, side effects
Prilosec OTC 10 4 reviews for Prilosec OTC to treat Indigestion
OTC C N
Generic name:
omeprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
aluminum hydroxide / magnesium carbonate 9.7 3 reviews for aluminum hydroxide / magnesium carbonate to treat Indigestion
OTC N N
Generic name:
aluminum hydroxide / magnesium carbonate systemic
Brand names:
Gaviscon Extra Strength, Acid Gone, Acid Gone Extra Strength
Drug class:
antacids
For consumers:
dosage, interactions, side effects
aluminum hydroxide / magnesium hydroxide / simethicone 9.5 3 reviews for aluminum hydroxide / magnesium hydroxide / simethicone to treat Indigestion
OTC N N
Generic name:
aluminum hydroxide / magnesium hydroxide / simethicone systemic
Brand names:
Mylanta, Gelusil, Almacone, Di-Gel, Mi-Acid, Milantex, Mintox, Mintox Plus, Mylanta Maximum Strength, Rulox
Drug class:
antacids
For consumers:
dosage, interactions, side effects
aluminum hydroxide / magnesium trisilicate 4.3 3 reviews for aluminum hydroxide / magnesium trisilicate to treat Indigestion
OTC N N
Generic name:
aluminum hydroxide / magnesium trisilicate systemic
Brand name:
Gaviscon Regular Strength Tablets
Drug class:
antacids
For consumers:
interactions, side effects
Tums Regular Strength 6.3 3 reviews for Tums Regular Strength to treat Indigestion
OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
Alka-Seltzer Original 7.0 2 reviews for Alka-Seltzer Original to treat Indigestion
OTC N N X
Generic name:
aspirin/citric acid/sodium bicarbonate systemic
Drug class:
salicylates
For consumers:
interactions, side effects
aspirin/citric acid/sodium bicarbonate 7.0 2 reviews for aspirin/citric acid/sodium bicarbonate to treat Indigestion
OTC N N X
Generic name:
aspirin/citric acid/sodium bicarbonate systemic
Brand names:
Alka-Seltzer Original, Alka-Seltzer Extra Strength
Drug class:
salicylates
For consumers:
interactions, side effects
Gaviscon Extra Strength 10 2 reviews for Gaviscon Extra Strength to treat Indigestion
OTC N N
Generic name:
aluminum hydroxide / magnesium carbonate systemic
Drug class:
antacids
For consumers:
dosage, interactions, side effects
nizatidine 10 2 reviews for nizatidine to treat Indigestion
Rx/OTC B N
Generic name:
nizatidine systemic
Brand name:
Axid AR
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Prilosec 8.5 2 reviews for Prilosec to treat Indigestion
Rx C N
Generic name:
omeprazole systemic
Drug class:
proton pump inhibitors
For consumers:
dosage, interactions, side effects
For professionals:
Prescribing Information
Titralac 10 2 reviews for Titralac to treat Indigestion
OTC N N
Generic name:
calcium carbonate systemic
Drug class:
antacids, minerals and electrolytes
For consumers:
dosage, interactions, side effects
calcium carbonate / magnesium hydroxide 9.0 1 review for calcium carbonate / magnesium hydroxide to treat Indigestion
OTC C N
Generic name:
calcium carbonate / magnesium hydroxide systemic
Brand names:
Masanti Supreme, Mi-Acid Double Strength, Mylanta Supreme, Rolaids Regular Strength, Rolaids Ultra Strength
Drug class:
antacids
For consumers:
dosage, interactions, side effects
cimetidine 9.0 1 review for cimetidine to treat Indigestion
Rx/OTC B N X
Generic name:
cimetidine systemic
Brand name:
Tagamet HB
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects
For professionals:
AHFS DI Monograph, Prescribing Information
Gaviscon Regular Strength Tablets 2.0 1 review for Gaviscon Regular Strength Tablets to treat Indigestion
OTC N N
Generic name:
aluminum hydroxide / magnesium trisilicate systemic
Drug class:
antacids
For consumers:
interactions, side effects
Gelusil 9.0 1 review for Gelusil to treat Indigestion
OTC N N
Generic name:
aluminum hydroxide / magnesium hydroxide / simethicone systemic
Drug class:
antacids
For consumers:
dosage, interactions, side effects
Mylanta 0.0 1 review for Mylanta to treat Indigestion
OTC N N
Generic name:
aluminum hydroxide / magnesium hydroxide / simethicone systemic
Drug class:
antacids
For consumers:
dosage, interactions, side effects
Pepcid AC Chewable Tablets 9.0 1 review for Pepcid AC Chewable Tablets to treat Indigestion
OTC B N
Generic name:
famotidine systemic
Drug class:
H2 antagonists
For consumers:
dosage, interactions, side effects

Frequently asked questions

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Topics under Indigestion

Alternative treatments for Indigestion

The following products are considered to be alternative treatments or natural remedies for Indigestion. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However, there may be historical, cultural or anecdotal evidence linking their use to the treatment of Indigestion.

Learn more about Indigestion

Care guides

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Rating For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).
Activity Activity is based on recent site visitor activity relative to other medications in the list.
Rx Prescription only.
OTC Over-the-counter.
Rx/OTC Prescription or Over-the-counter.
Off-label This medication may not be approved by the FDA for the treatment of this condition.
EUA An Emergency Use Authorization (EUA) allows the FDA to authorize unapproved medical products or unapproved uses of approved medical products to be used in a declared public health emergency when there are no adequate, approved, and available alternatives.
Expanded Access Expanded Access is a potential pathway for a patient with a serious or immediately life-threatening disease or condition to gain access to an investigational medical product (drug, biologic, or medical device) for treatment outside of clinical trials when no comparable or satisfactory alternative therapy options are available.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
M The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication.
U CSA Schedule is unknown.
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.