Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate) Drug Interactions
A total of 416 drugs are known to interact with Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate).
- 52 major drug interactions
- 291 moderate drug interactions
- 73 minor drug interactions
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Most frequently checked interactions
View interaction reports for Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate) and the medicines listed below.
- amlodipine
- aspirin
- atorvastatin
- Benadryl (diphenhydramine)
- gabapentin
- hydrochlorothiazide
- ibuprofen
- levothyroxine
- lisinopril
- loratadine
- melatonin
- metformin
- omeprazole
- pantoprazole
- ranitidine
- tramadol
- trazodone
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin D3 (cholecalciferol)
Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate) alcohol/food interactions
There are 2 alcohol/food interactions with Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate)
Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate) disease interactions
There are 11 disease interactions with Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate) which include:
- sodium/water balance
- coagulation
- asthma
- GI toxicity
- renal dysfunction
- Reye's syndrome
- acid/base balance
- anemia
- dialysis
- G-6-PD deficiency
- hepatotoxicity
More about Alka-Seltzer Original (aspirin / citric acid / sodium bicarbonate)
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.