Comparing Sertraline vs Pristiq
| Sertraline | Pristiq (desvenlafaxine) |
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| Sertraline | Pristiq (desvenlafaxine) |
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Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
Prescription only
Prescribed for Major Depressive Disorder, Depression. Pristiq may also be used for purposes not listed in this medication guide. |
Related suggestions Depression
Major Depressive Disorder
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| More about Sertraline | More about Pristiq (desvenlafaxine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Sertraline has an average rating of 7.3 out of 10 from a total of 4587 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
Pristiq has an average rating of 6.9 out of 10 from a total of 1132 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Sertraline side effects |
View all Pristiq side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Sertraline prices |
View all Pristiq prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Zoloft |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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66 hours |
11 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 674 drugs are known to interact with Sertraline:
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A total of 483 drugs are known to interact with Pristiq:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 30, 1991 |
February 29, 2008 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.