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User Reviews for Pristiq

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Pristiq.

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Condition Avg. Ratings Reviews Compare
Depression
7.3
   
585 reviews 80 medications
Major Depressive Disorder
6.3
   
44 reviews 46 medications
Summary of Pristiq reviews 6.8 629 reviews

Reviews for Pristiq

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For Depression "prestiq 200mg . Maybe it was way too strong. The side effects out weighed the effect by absolute miles. Side effects were I couldn't stand up for longer than 4 hours , got dizzy spells ..dropped work from 8-10 hrs/day too maybe 12 hours a week, had really bad nightmares and really bad mood swings I felt suicidal, and continued to have those thoughts for next 3 weeks. I gained 6kg in 3 weeks . I had to take valium and mersondyl forte for the down times . I had erection problems , so viagra to counter act with that. . I cannot say anything good about it The best remedy was to start walking , biking , sport, record times and try and beat those times , achievements . I need a sense of accomplishment. valium for down times , had to have it anyway"

   
2.0

creams (taken for 1 to 6 months) November 11, 2017

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For Depression "Day 4 of 150mg of pristiq Went from 225mg effexor to 150mg pristiq Effexor hasn't worked for months Having weird day .. Day 1 ok, day 2 ok, day3 tired all days But I still don't know what to do - no motivation to do anything still Sad and overwhelmed by everything Depression Anxiety is so hard for me to manage and understand nothing in my life is the same....hope is all I've got"

CharleeBrown (taken for less than 1 month) November 11, 2017

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For Depression "I was on 50mg first...I was crazy then I went on 100mg. Changed my life. I was actually living! ! When I missed a few days, I thought it was making me sick, but never missed any doses. Then my doctor cancelled on me 3 days in a row . At that point it was 6 days, so I said screw it, I'll stay off them and I did fine. Wasn't sickly...didn't go crazy. I was fine. This past 3.5 years of being off it, I've gone way down hill. So I'm excited about going back on them and getting a life back. I tell you, before I went on them I was in a really bad place. PTSD, from my child hood, my brother killed him self, had none in my life. Got on pills started jogging and working out, eating good, because I felt good for once. Lost 50lbs. Getting back"

   
9.0

Hollzzz November 8, 2017

5 users found this comment helpful.
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For Depression "This drug made me feel as if I was always running out of time, as if I couldn't stop and enjoy anything. I felt down most of the time on it; not significantly so but enough to make want to quit it."

   
3.0

roger_d_1989 (taken for 1 to 6 months) October 30, 2017

3 users found this comment helpful.
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For Depression "Hi, this drug I feel seems to stabilise your mood/brain and does make you happy. Not like a drug , it corrects my brain to how I'm meant to feel, (some people hopefully understand what I mean-rather than feeling down ,just want to be alone, quiet, low). I think I had anxiety, mild depression & insomnia. I feel more focused and feel my true self. I'm 35, a professional, single fit and healthy. Death divorce boom. Just battled on, shattered, hiding my feelings until finally just giving this a chance. After 1 month I'm on 100mg of pristiq a day and love how it's giving me my life back!"

   
9.0

Snappa (taken for 1 to 6 months) October 25, 2017

9 users found this comment helpful.
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For Major Depressive Disorder "Pristiq changed my life. Made me feel like a normal happy person. Side effects were an annoying headache for the first 2 days. No more symptoms once I had come off it."

DeeDee1388 October 13, 2017

4 users found this comment helpful.
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For Depression "Put it this way, I've no intention of ever coming off Pristiq. Almost a year and I'm a new woman. It was my first 4th dip of rock bottom but I won't have another one. Depression has such a stigma! What about 'neurotransmitter condition' !!!"

   
10

NoraHmcc October 10, 2017

13 users found this comment helpful.
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For Depression "Once you start pristiq you're on it for the rest of your life, and what's worst, you need to up your dose every year. It's a nightmare. You can never quit it, not even gradually. Withdrawal or refusal to increase your dose will destroy you. Avoid it."

   
1.0

Do not start pristiq (taken for 5 to 10 years) September 23, 2017

11 users found this comment helpful.
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For Depression "Pristiq is a horrible drug. Caused me to be off work for 9 months due to the side effects, I had insomia didn't sleep for 2 weeks, gave me restless leg syndrome, felt agitated, my mood was super down. I would not recommend it to anyone."

   
1.0

Notgoos September 21, 2017

8 users found this comment helpful.
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For Depression "I thought I could manage without medication but after 2 months I fell into the black hole yet again. This time my Doctor put me on Pristiq and it gave me an unexpected benefit. A few years ago I had a right hip replacement but it kept pulling out and I would fall down. It then dislocated altogether and I had to have another operation and after a year it dislocated again. This year Jan 2017 I had my other hip replaced. Not surprisingly the fear of falling was extreme. After 4 weeks on Pristiq I found I can walk without aids. I would like Pristiq to help stop the negative thoughts that roll around my head however I will stay on Pristiq regardless because it is the difference in being able to walk or be incapacitated by fear and anxiety."

   
10

Whirling dervish September 15, 2017

10 users found this comment helpful.
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For Depression "This medicine has changed my life! I feel like I am living life again instead of surviving. I used to wake up every day fearful of everything. It was so bad that I had to take 6 weeks off work. This medicine has changed me. I wake up every morning happy and very energized. I started taking this medicine in April of 2017 and its the best decision I have ever made. I was always skeptical of taking medicine but I am so glad I decided to."

   
10

Anonymous September 11, 2017

26 users found this comment helpful.
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For Depression "This drug has changed me back to the person I recall being 20 yrs ago. For the first time in years I've been waking up early with energy ready to take on the day. I have a 1 year old toddler and a beautiful wife and I want to be all I can for them and I don't think it would be possible without the assistance of this medication. I am also a surgeon and lead a stressful lifestyle so I need all the help I can get. There's been a lot of trial error along the way... My Advice: keep trying different anti-depressants and by 12 months there is a 90% chance you'll find the right one for you. If the medication gives you a significant improvement (but falls short of 100%) stick with it and sort the rest out with psychotherapy."

   
10

ChloeDrugs (taken for less than 1 month) September 7, 2017

23 users found this comment helpful.
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For Depression "SCARIEST ANTI-DEPPRESANT I'VE EVER TRIED! Put me into the stratosphere of anxiety/depression-became suicidal-anything-or nothing is better than this!"

   
1.0

ebelle (taken for less than 1 month) September 4, 2017

9 users found this comment helpful.
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For Depression "Pristiq has been the most effective drug I've came across in my life for this mental illness! Only side effect is because it's a timed release, if you miss 1 day taking it you will feel like a train hit you. Otherwise it's the most stable I've ever felt!"

   
10

Clinical depression sucks (taken for 1 to 6 months) September 1, 2017

11 users found this comment helpful.
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For Major Depressive Disorder "I am 34, its my first week on it. I didn't realise how bad things really were inside my head until now. At first I had 2 days of nauseous bouts but by the third day I felt less caught in a loop and yesterday I went to 100mg and while thinking of an old friend I had a slip back in a moment of time and with a good memory in my brain I felt a rush of elation inside me like butterflies. I actually felt something. I've been suffering for so long and it almost seems too good to be true. I'm so thankful."

Annarexsickk (taken for less than 1 month) August 17, 2017

7 users found this comment helpful.
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For Major Depressive Disorder "Its been nearly 2 years on various doses of Pristiq, and 100mg each day works best for my mind. Thankfully. I have some side effects that annoy me a lot, like no appetite, nausea, gut problems & worst of all- killed my libido this whole time. It simply ceased to exist. I continue to take my meds. I'm a widow raising a 12 year old for last 7 years after my Husband died suddenly very suddenly of swine flu. So much has been lost from that day. Inevitably it took its toll on me. Not a complete person anymore. Its like I feel asexual... But I am alive and kicking"

   
7.0

Elaine is my real name (taken for 2 to 5 years) August 4, 2017

3 users found this comment helpful.
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For Depression "This drug made my executive functioning a lot better, but it also almost immediately made me super down and caused partial seizures (I have no history of epilepsy). It may have triggered an episode of psychosis as well but I am still uncertain whether it was a psychotic episode or a seizure as I also lost control and sensation in my limbs while hallucinating before losing consciousness completely. I would not recommend this drug."

   
1.0

rongeromy (taken for 1 to 6 months) August 1, 2017

17 users found this comment helpful.
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For Major Depressive Disorder "Pristiq, BRAND NAME ONLY, I give 10 plus. Best thing out there for me. 50mg - barely any side effects, crazy night sweats, but sex drive in check - key for happy soul and relationships. Do not take generic, I had a serious relapse in depression almost put me in the hospital. Mind you, it took 3 months for us to realize what was happening so be careful! The generic is too new to find much information and if you goggle how inadequate testing is, you'll be persuaded not to use. Found Pristiq after decades of different cocktails until my new DR. had me take a genetic test - not ancestry test. I highly suggest, super informative regarding how your body breakdown psych. Meds. Thank you for sharing - today I live because I am not alone"

DD in the rabbithole (taken for 6 months to 1 year) July 31, 2017

10 users found this comment helpful.
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For Depression "This was a big change in life with 50 mg taken at night for one week then went to 25mg in am. It's been 6 months and things are great. I take also First Nutrients Nutrivie a natural plant base every day with 5 oz of water and that has been the best thing for depression and anxiety! I wish more people new! It gives you your life back. Hoping everyone can feel good again."

   
6.0

Kingbear67 July 28, 2017

23 users found this comment helpful.
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For Depression "I started pristiq 3 months ago and it has changed my life! I finally feel like I want to live. It all started with taking a DNA test and it recommended pristiq. I don't get those really low days anymore. I love pristiq! I never thought I would feel better after trying medication after medication."

   
10

Katie4717 July 26, 2017

29 users found this comment helpful.
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For Depression "I have been on 100mg of Pristiq for three years for depression and anxiety. Without question it has changed my life incredibly. I waited 47 years to have the courage to take an antidepressant and wish with all my heart I had met this medication in my 20's. I started on 50mg but after a two months reluctantly headed up to 100 ... my reservations were for nothing ... this medication has worked beautifully for me. I did have side effects in the first few weeks, beating heart, very thirsty and slight headaches, but they passed quickly and I have been amazed by its strength ever since. I have had some serious life crises to deal with in the past three years ... and often feared the medication would not be able to 'hold' me ... it always has. I have an amazing therapist who I saw for the first two years but no longer need that support, the medication is enough. I used to have so many concerns about taking any such medications - was frequently turned away from them by what I'd read as horror stories online ... I wanted to let you know ... it's not for all of us ... some of us do have great reviews ... maybe not enough of us drop back to pass them on because we got busy with our new lives where wellness is the new normal. I never worry about coming off them, I don't care if I have to take them forever ... as long as I feel this good I'm not ending my relationship with them ..."

   
10

Finally healthy (taken for 2 to 5 years) July 26, 2017

42 users found this comment helpful.
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For Depression "After five antidepressants this is the one that brought me back to myself. I'm not 100%, but I was at 40% and now 80% myself. I am able to laugh again, appreciate the beauty of the out doors, and to enjoy my kids without yelling due to being constantly overwhelmed. My insurance switched me to generic pristiq and within a month I started feeling the anxiety and depression return. I was back to feeling like a zombie and in addition had withdraw symptoms from stopping the name brand pristiq including headaches, fatigue, muscle aches, and insomnia. I have switched back to name brand 4 days ago and feel a tiny bit better, but praying name brand pristiq kicks back in quicker. No generic!"

   
7.0

Plutohomer (taken for 2 to 5 years) July 3, 2017

37 users found this comment helpful.
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For Depression "Originally I would have given this drug 10/10. I had anxiety so bad that at one point I could not even leave the house without having a panic attack. On Pristiq, from my experience, a few wonderful things will happen: 1. You couldn't have a panic attack if you tried to talk yourself into it. 2. You will not gain weight (I lost weight originally and then went back to normal after 6 months). 3. Your depression will subside - though there is a BUT with that. The not great: 1. It is really hard to get off of, brain zaps, no step down options. 2. You become a bit zombie-like, lost creativity etc. A lot of not caring so much. 3. Sexual side-effects, though they do improve over time. Solid 5/10"

   
5.0

beesy24 (taken for 2 to 5 years) June 21, 2017

27 users found this comment helpful.
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For Depression "I took one dose and ended up in the ER with a horrible pounding, predominately right sided migraine. Along with about 6 hours of vomiting. It had to have been the worst migraine of my life."

   
1.0

xixi (taken for less than 1 month) June 15, 2017

15 users found this comment helpful.
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For Major Depressive Disorder "I have been taking this medication for almost a year. I have tried every depression medication on the planet. Seriously, I have tried ALL of them. I suffer from crippling anxiety so I needed something that would help my depression and my anxiety. This medication has worked quite well for both. I have noticed a few things since I started taking these. My sex drive is completely gone. I have constipation issues and quite a dry mouth. Losing my sex drive has been completely terrible, I can't deal with crippling anxiety any longer, so it was worth it. This medication is pretty pricey, about $45 a month with insurance. Before I was taking this, I paid about $4 for 3 months. My doctor gave me a coupon/card, so when I use that it only costs me $4"

   
8.0

CallieAllieCat June 7, 2017

5 users found this comment helpful.
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