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User Reviews for Pristiq

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care. Learn more about Pristiq.

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User Ratings

10
   
27%(162)
9
   
22%(130)
8
   
15%(91)
7
   
9%(50)
6
   
6%(33)
5
   
5%(29)
4
   
2%(10)
3
   
4%(22)
2
   
4%(21)
1
   
10%(59)

Pristiq Rating Summary

7.3/10 Average Rating

607 Ratings with 585 User Reviews

What next?Compare all 217 medications used in the treatment of Depression.

Reviews for Pristiq to treat Depression

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"prestiq 200mg . Maybe it was way too strong. The side effects out weighed the effect by absolute miles. Side effects were I couldn't stand up for longer than 4 hours , got dizzy spells ..dropped work from 8-10 hrs/day too maybe 12 hours a week, had really bad nightmares and really bad mood swings I felt suicidal, and continued to have those thoughts for next 3 weeks. I gained 6kg in 3 weeks . I had to take valium and mersondyl forte for the down times . I had erection problems , so viagra to counter act with that. . I cannot say anything good about it The best remedy was to start walking , biking , sport, record times and try and beat those times , achievements . I need a sense of accomplishment. valium for down times , had to have it anyway"

   
2.0

creams (taken for 1 to 6 months) November 11, 2017

0 users found this comment helpful.
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"Day 4 of 150mg of pristiq Went from 225mg effexor to 150mg pristiq Effexor hasn't worked for months Having weird day .. Day 1 ok, day 2 ok, day3 tired all days But I still don't know what to do - no motivation to do anything still Sad and overwhelmed by everything Depression Anxiety is so hard for me to manage and understand nothing in my life is the same....hope is all I've got"

CharleeBrown (taken for less than 1 month) November 11, 2017

1 users found this comment helpful.
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"I was on 50mg first...I was crazy then I went on 100mg. Changed my life. I was actually living! ! When I missed a few days, I thought it was making me sick, but never missed any doses. Then my doctor cancelled on me 3 days in a row . At that point it was 6 days, so I said screw it, I'll stay off them and I did fine. Wasn't sickly...didn't go crazy. I was fine. This past 3.5 years of being off it, I've gone way down hill. So I'm excited about going back on them and getting a life back. I tell you, before I went on them I was in a really bad place. PTSD, from my child hood, my brother killed him self, had none in my life. Got on pills started jogging and working out, eating good, because I felt good for once. Lost 50lbs. Getting back"

   
9.0

Hollzzz November 8, 2017

5 users found this comment helpful.
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"This drug made me feel as if I was always running out of time, as if I couldn't stop and enjoy anything. I felt down most of the time on it; not significantly so but enough to make want to quit it."

   
3.0

roger_d_1989 (taken for 1 to 6 months) October 30, 2017

3 users found this comment helpful.
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"Hi, this drug I feel seems to stabilise your mood/brain and does make you happy. Not like a drug , it corrects my brain to how I'm meant to feel, (some people hopefully understand what I mean-rather than feeling down ,just want to be alone, quiet, low). I think I had anxiety, mild depression & insomnia. I feel more focused and feel my true self. I'm 35, a professional, single fit and healthy. Death divorce boom. Just battled on, shattered, hiding my feelings until finally just giving this a chance. After 1 month I'm on 100mg of pristiq a day and love how it's giving me my life back!"

   
9.0

Snappa (taken for 1 to 6 months) October 25, 2017

9 users found this comment helpful.
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"Put it this way, I've no intention of ever coming off Pristiq. Almost a year and I'm a new woman. It was my first 4th dip of rock bottom but I won't have another one. Depression has such a stigma! What about 'neurotransmitter condition' !!!"

   
10

NoraHmcc October 10, 2017

13 users found this comment helpful.
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"Once you start pristiq you're on it for the rest of your life, and what's worst, you need to up your dose every year. It's a nightmare. You can never quit it, not even gradually. Withdrawal or refusal to increase your dose will destroy you. Avoid it."

   
1.0

Do not start pristiq (taken for 5 to 10 years) September 23, 2017

10 users found this comment helpful.
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"Pristiq is a horrible drug. Caused me to be off work for 9 months due to the side effects, I had insomia didn't sleep for 2 weeks, gave me restless leg syndrome, felt agitated, my mood was super down. I would not recommend it to anyone."

   
1.0

Notgoos September 21, 2017

8 users found this comment helpful.
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"I thought I could manage without medication but after 2 months I fell into the black hole yet again. This time my Doctor put me on Pristiq and it gave me an unexpected benefit. A few years ago I had a right hip replacement but it kept pulling out and I would fall down. It then dislocated altogether and I had to have another operation and after a year it dislocated again. This year Jan 2017 I had my other hip replaced. Not surprisingly the fear of falling was extreme. After 4 weeks on Pristiq I found I can walk without aids. I would like Pristiq to help stop the negative thoughts that roll around my head however I will stay on Pristiq regardless because it is the difference in being able to walk or be incapacitated by fear and anxiety."

   
10

Whirling dervish September 15, 2017

10 users found this comment helpful.
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"This medicine has changed my life! I feel like I am living life again instead of surviving. I used to wake up every day fearful of everything. It was so bad that I had to take 6 weeks off work. This medicine has changed me. I wake up every morning happy and very energized. I started taking this medicine in April of 2017 and its the best decision I have ever made. I was always skeptical of taking medicine but I am so glad I decided to."

   
10

Anonymous September 11, 2017

26 users found this comment helpful.
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"This drug has changed me back to the person I recall being 20 yrs ago. For the first time in years I've been waking up early with energy ready to take on the day. I have a 1 year old toddler and a beautiful wife and I want to be all I can for them and I don't think it would be possible without the assistance of this medication. I am also a surgeon and lead a stressful lifestyle so I need all the help I can get. There's been a lot of trial error along the way... My Advice: keep trying different anti-depressants and by 12 months there is a 90% chance you'll find the right one for you. If the medication gives you a significant improvement (but falls short of 100%) stick with it and sort the rest out with psychotherapy."

   
10

ChloeDrugs (taken for less than 1 month) September 7, 2017

23 users found this comment helpful.
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"SCARIEST ANTI-DEPPRESANT I'VE EVER TRIED! Put me into the stratosphere of anxiety/depression-became suicidal-anything-or nothing is better than this!"

   
1.0

ebelle (taken for less than 1 month) September 4, 2017

9 users found this comment helpful.
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"Pristiq has been the most effective drug I've came across in my life for this mental illness! Only side effect is because it's a timed release, if you miss 1 day taking it you will feel like a train hit you. Otherwise it's the most stable I've ever felt!"

   
10

Clinical depression sucks (taken for 1 to 6 months) September 1, 2017

11 users found this comment helpful.
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"This drug made my executive functioning a lot better, but it also almost immediately made me super down and caused partial seizures (I have no history of epilepsy). It may have triggered an episode of psychosis as well but I am still uncertain whether it was a psychotic episode or a seizure as I also lost control and sensation in my limbs while hallucinating before losing consciousness completely. I would not recommend this drug."

   
1.0

rongeromy (taken for 1 to 6 months) August 1, 2017

17 users found this comment helpful.
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"This was a big change in life with 50 mg taken at night for one week then went to 25mg in am. It's been 6 months and things are great. I take also First Nutrients Nutrivie a natural plant base every day with 5 oz of water and that has been the best thing for depression and anxiety! I wish more people new! It gives you your life back. Hoping everyone can feel good again."

   
6.0

Kingbear67 July 28, 2017

23 users found this comment helpful.
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"I started pristiq 3 months ago and it has changed my life! I finally feel like I want to live. It all started with taking a DNA test and it recommended pristiq. I don't get those really low days anymore. I love pristiq! I never thought I would feel better after trying medication after medication."

   
10

Katie4717 July 26, 2017

29 users found this comment helpful.
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"I have been on 100mg of Pristiq for three years for depression and anxiety. Without question it has changed my life incredibly. I waited 47 years to have the courage to take an antidepressant and wish with all my heart I had met this medication in my 20's. I started on 50mg but after a two months reluctantly headed up to 100 ... my reservations were for nothing ... this medication has worked beautifully for me. I did have side effects in the first few weeks, beating heart, very thirsty and slight headaches, but they passed quickly and I have been amazed by its strength ever since. I have had some serious life crises to deal with in the past three years ... and often feared the medication would not be able to 'hold' me ... it always has. I have an amazing therapist who I saw for the first two years but no longer need that support, the medication is enough. I used to have so many concerns about taking any such medications - was frequently turned away from them by what I'd read as horror stories online ... I wanted to let you know ... it's not for all of us ... some of us do have great reviews ... maybe not enough of us drop back to pass them on because we got busy with our new lives where wellness is the new normal. I never worry about coming off them, I don't care if I have to take them forever ... as long as I feel this good I'm not ending my relationship with them ..."

   
10

Finally healthy (taken for 2 to 5 years) July 26, 2017

42 users found this comment helpful.
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"After five antidepressants this is the one that brought me back to myself. I'm not 100%, but I was at 40% and now 80% myself. I am able to laugh again, appreciate the beauty of the out doors, and to enjoy my kids without yelling due to being constantly overwhelmed. My insurance switched me to generic pristiq and within a month I started feeling the anxiety and depression return. I was back to feeling like a zombie and in addition had withdraw symptoms from stopping the name brand pristiq including headaches, fatigue, muscle aches, and insomnia. I have switched back to name brand 4 days ago and feel a tiny bit better, but praying name brand pristiq kicks back in quicker. No generic!"

   
7.0

Plutohomer (taken for 2 to 5 years) July 3, 2017

37 users found this comment helpful.
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"Originally I would have given this drug 10/10. I had anxiety so bad that at one point I could not even leave the house without having a panic attack. On Pristiq, from my experience, a few wonderful things will happen: 1. You couldn't have a panic attack if you tried to talk yourself into it. 2. You will not gain weight (I lost weight originally and then went back to normal after 6 months). 3. Your depression will subside - though there is a BUT with that. The not great: 1. It is really hard to get off of, brain zaps, no step down options. 2. You become a bit zombie-like, lost creativity etc. A lot of not caring so much. 3. Sexual side-effects, though they do improve over time. Solid 5/10"

   
5.0

beesy24 (taken for 2 to 5 years) June 21, 2017

27 users found this comment helpful.
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"I took one dose and ended up in the ER with a horrible pounding, predominately right sided migraine. Along with about 6 hours of vomiting. It had to have been the worst migraine of my life."

   
1.0

xixi (taken for less than 1 month) June 15, 2017

15 users found this comment helpful.
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"I've been on 100mg Pristiq for 6 years for panic and depression. Prior, I had been on 150mg Effexor XR for 7 years. For panic, this drug is excellent. If you've experienced "brain shivers" or "shocks" when missing a dose on other medications, this one has managed to remove them, which I feel is great. I want to note, that you will get withdrawal headaches every so often on Pristiq which can be slept off. Over the years, I found that I had a more stable experience when taking my 100mg dose at intervals of 50mg at breakfast and the other 50mg at bedtime. This strategy attempts to keep your body with a consistent supply so you are "topped up" to minimize the withdrawl effects."

ExerciseToo June 7, 2017

25 users found this comment helpful.
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"I have been on pretty much every antidepressant that is out there. Nothing has really helped and the few times I felt a slight improvement in my condition, the side effects outweighed the benefits. Pristiq has been totally different. Within a week of starting it I see a positive change. My overall mood is better, I have more energy, and I am more productive. Also, when my mood does take a dip, it seems that the "bottom" has been raised. In other words, the lows aren't as low as they once were. I have only been on it a couple of weeks and I am told that I still may not be experiencing the full benefit, which is great considering how much better I already feel. No side effects whatsoever. Very grateful for this medication."

   
9.0

Much Better (taken for less than 1 month) June 5, 2017

46 users found this comment helpful.
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"I was on Celexa for 5 years before it stopped working. Took the DNA test and celexa and others were in red but pristiq was green. Pristiq I took for 2 months and it was the worst hell I've ever gone through. Ditched the DNA test as it's garbage and been on zoloft for 5 months with good results again"

Matt4567 (taken for 1 to 6 months) May 18, 2017

20 users found this comment helpful.
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"I am almost 24 and have been on pristiq for about 5 weeks. I am now up to 100 mg but started at 50. I have no negative side effects besides maybe a light headache. I have been on over 10 anti-depressents in the past with nothing but bad side effects and had sworn them off 6 years ago. Nothing worked for my anxiety and depression in the past besides of course my take as needed klonopin. Pristig has been good. No side effects or appetite increase. I am also going through an extremely tough and stressful time in life at this point and once I was upped to 100 mg, I have noticed an increase in my mood positively. Like I said, I had sworn off meds for years, but I feel like this one may be working. Give it a try and work with your doctor"

   
8.0

Nat attack (taken for 1 to 6 months) April 29, 2017

39 users found this comment helpful.
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"I tried Pristiq, which had been listed on my Genesight review in the positive column. Was on it for three weeks and had to stop as I had developed hypermania: no sleep, talkative, spending, messy, walking around confused and generally felt very high. Felt very unsafe driving and was also eating everything in sight until I had a stomach ache. Gained weight and just felt plain bloated. While I recognized that something was wrong, I was not thinking straight enough too judge. Fortunately, the prescriber recognized it and I am now stopped 3 days. Don't feel great, but I am glad I was not on it long enough to have withdrawal problems."

   
2.0

jmsagain April 29, 2017

25 users found this comment helpful.
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