Comparing Prolia vs Reclast
| Prolia | Reclast |
|
|---|
| Prolia (denosumab) | Reclast (zoledronic acid) |
|
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Prescription only
Prolia is an injection that can be self-administered once every six months for the treatment of osteoporosis. It has been associated with an increased risk of fractures on discontinuation... View more |
Prescription only
Reclast may be used to treat or prevent osteoporosis caused by menopause, steroid use, or gonadal failure, in the treatment of Paget's disease, and to increase bone mineral density in men. Reclast... View more |
Related suggestions Osteoporosis
Popular comparisons
|
|||||||||||||||
| More about Prolia (denosumab) | More about Reclast (zoledronic acid) | ||||||||||||||||
| Generic Status | |||||||||||||||||
|
No lower-cost generic available |
|||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
|
Prolia has an average rating of 2.7 out of 10 from a total of 342 ratings on Drugs.com. 14% of reviewers reported a positive effect, while 79% reported a negative effect. |
Reclast has an average rating of 5.1 out of 10 from a total of 228 ratings on Drugs.com. 37% of reviewers reported a positive effect, while 43% reported a negative effect. |
||||||||||||||||
| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
|
See also: Prolia side effects in more detail. |
Common side effects include:
See also: Reclast side effects in more detail. |
||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Prolia prices |
View all Reclast prices and generic prices |
||||||||||||||||
| Dosage Form(s) Available | |||||||||||||||||
|
|
||||||||||||||||
| Brand Names | |||||||||||||||||
| Other denosumab brands include: Xgeva | Other zoledronic acid brands include: Aclasta, Zometa | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
|
609.6 hours |
N/A |
||||||||||||||||
| CSA Schedule ** View glossary of terms | |||||||||||||||||
|
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
||||||||||||||||
| Pregnancy Category | |||||||||||||||||
|
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
||||||||||||||||
| Drug Interactions | |||||||||||||||||
|
A total of 257 drugs are known to interact with Prolia:
|
A total of 115 drugs are known to interact with Reclast:
|
||||||||||||||||
| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
|
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
|
June 01, 2010 |
N/A |
||||||||||||||||
| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
|
N/A |
N/A |
||||||||||||||||
| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.