Comparing Pristiq vs Vortioxetine

For Depression On my first day of Pristiq, I noticed an immediate surge of energy (coupled with a racing heart and a feeling of disorientation). I am somewhat sensitive to mediciations generally so I was prepared to inherit some of the side effects. What I have experienced in my first week is tiredness, irritability/difficult sleeping, grinding teeth, nausea (vomited 5 times on night 1, which settled on second day), loss of appetite and general stiffness around my neck and back. I trust these symptoms will settle in the coming weeks but thought it may be valuable to share my first week, for those who are a little sensitive to medication. In regards to my mental state, I can safely say my mood has been moderately chilled, unfazed and without any anxiety.

For Depression I am a 77 year old male. My Grandfather and my Father suffered from Depression. I have suffered from depression all of my life. I was first diagnosed with severe clinical depression about 1975. I was put on ELAVIL and the results were very good and I took it for about 12 years. At that time the ELAVIL stopped working and my Doctor put me on NORTRIPTYLINE. That seemed to stop the depression and worked for a long time. When it stopped working, my Doctor put me on PAXCIL. Then, a Psychiatrist added WELLBUTRIN XL. Then my PDOC replaced the generic PAXCIL with PRISTIQ. For the first time in 40 years, my depression has gone!

For Depression I've had zero nausea, but zero sex drive and I have a hard time concentrating at work. I've been taking 20 mg for about 6 weeks. I take it at bedtime. I have been very sluggish and have gained about 10 pounds. I also have terrible gas so I have to take gas pills daily. It has helped with my depression, but my job is suffering because I cannot concentrate at all. I'm thinking of asking my doctor to change my med because I will get fired soon if I keep this up! I no longer want to kill myself, but soon I will be obese, unemployed and sleepy. Then I will be more depressed...

For Depression Hello: I have taken 5mg doses once a day for the past 2 1/2 weeks for High blood pressure and stress. I noticed no effect and had none of the bad side effects I've heard of here. One thing - I do think I am dreaming more. Not nightmares but very vivid dreams. I may be a little calmer during the day but I can hardly notice *any* changes. I will stay with this for a while longer and see what happens.