Comparing Premarin vs Vagifem
| Premarin (conjugated estrogens) | Vagifem (estradiol) |
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| Premarin (conjugated estrogens) | Vagifem (estradiol) |
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Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis, Abnormal Uterine Bleeding, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Prescription only
Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Vagifem may also be used for purposes not listed in this medication guide. |
Related suggestions Atrophic Vaginitis
Atrophic Urethritis
Popular comparisons
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| More about Premarin (conjugated estrogens) | More about Vagifem (estradiol) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Premarin has an average rating of 7.7 out of 10 from a total of 84 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 17% reported a negative effect. |
Vagifem has an average rating of 6.0 out of 10 from a total of 102 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Premarin side effects |
View all Vagifem side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Premarin prices |
View all Vagifem prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other conjugated estrogens brands include: Premarin Intravenous | Other estradiol brands include: Estrace Vaginal Cream, Estring, Imvexxy, Yuvafem | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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N/A |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 355 drugs are known to interact with Premarin:
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A total of 258 drugs are known to interact with Vagifem:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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May 08, 1942 |
March 26, 1999 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Estrace
Estrace (estradiol) is used to treat symptoms of menopause such as hot flashes and vaginal dryness ...
Estradiol Patch
Estradiol Patch is used for atrophic urethritis, atrophic vaginitis, breast cancer, palliative ...
Botox
Botox is used cosmetically to reduce facial lines and wrinkles and for medical purposes for ...
Estrace Vaginal Cream
Estrace Vaginal Cream is used for atrophic urethritis, atrophic vaginitis
Vagifem
Vagifem vaginal inserts are used treat menopause symptoms such as dryness, burning, and irritation ...
Prempro
Prempro (conjugated estrogens and medroxyprogesterone) is used to treat the symptoms of menopause ...
Climara
Climara (estradiol) skin patches are used to treat symptoms of menopause such as hot flashes and ...
Conjugated estrogens topical
Conjugated estrogens topical is used for atrophic urethritis, atrophic vaginitis, postmenopausal symptoms
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.