Phentermine Alternatives Compared
| Phentermine | Topiramate | Wegovy (semaglutide) |
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| Phentermine | Topiramate | Wegovy (semaglutide) |
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Prescription only
Phentermine may be used short-term as an aid to weight loss; however, it can be addictive and tolerance may develop to its weight-losing effects, rendering it less effective with time. Prescribed for... View more |
Prescription only
Topiramate may be prescribed either alone or in combination with other medications for the treatment of certain types of epilepsy, or it may be given for the prevention of migraines. Drowsiness is a... View more |
Prescription only
Prescribed for Weight Loss (Obesity/Overweight), Cardiovascular Risk Reduction. Wegovy may also be used for purposes not listed in this medication guide. |
Related suggestions Weight Loss (Obesity/Overweight)
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| More about Phentermine | More about Topiramate | More about Wegovy (semaglutide) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Phentermine has an average rating of 8.6 out of 10 from a total of 3016 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 5% reported a negative effect. |
Topiramate has an average rating of 6.3 out of 10 from a total of 1338 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 28% reported a negative effect. |
Wegovy has an average rating of 7.6 out of 10 from a total of 519 ratings on Drugs.com. 66% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Phentermine side effects |
View all Topiramate side effects |
View all Wegovy side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
View all Phentermine prices |
View all Topiramate prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| Adipex-P, Atti-Plex P, Lomaira | Eprontia, Qudexy XR, Topamax, Trokendi XR | Other semaglutide brands include: Ozempic, Rybelsus | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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20 hours |
56 hours |
168 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 196 drugs are known to interact with Phentermine:
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A total of 291 drugs are known to interact with Topiramate:
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A total of 275 drugs are known to interact with Wegovy:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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August 14, 1973 |
December 24, 1996 |
N/A |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
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| More Information | ||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.