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Phentermine and Loss Of Appetite: What Users Say

Brand names: Adipex-P, Lomaira, Atti-Plex P

Loss of appetite: mentioned by 90 users (3.0%)

Based on user experiences from 3,014 Phentermine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 26.7%
insomnia 9.8%
headaches 6.9%
anxiety 6.4%
constipation 4.5%
increased heart rate 3.6%
loss of appetite 3.0%
dizziness 2.7%
tremors 2.7%
nausea 2.6%

Reviews for Phentermine

Commonly mentioned side effects
  • Bug...
  • June 3, 2020

For Weight Loss (Obesity/Overweight) "I just started taking 37.5 mg of Phentermine yesterday for weight loss. After struggling with diets, exercise and medication weight gain, my doctor and I decided this was the best way to help me shed the 10-20 pounds I’ve been wanting to lose for at least 6 months. First and foremost, take this pill as early as you can because it did affect my sleep. On the first day, I only experienced light jitteriness, a little chest pain, and a headache. My appetite was lessened. Today (the second day) I am already down a pound, I’m not very hungry at all, and I only have mild jitters and a headache. Nothing that isn’t tolerable though. I plan on taking this for a total of 3 months only, so I’m hoping I’ll drop the excess weight I’ve gained and develop healthier practices while I’m on it. I will say that the increased energy is nice for someone who wasn’t sleeping well and then wasn’t motivated to move around."

8 / 10
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172 Report
  • Kat...
  • February 18, 2015

For Weight Loss (Obesity/Overweight) "I've been taking phentermine for 2 months and I have lost 22 pounds. I haven't exercised, just my normal active life as a mother and student. The only side effect I've had is severely dry mouth and no appetite. I literally force myself to eat something."

9 / 10
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124 Report
  • Bro...
  • Taken for less than 1 month
  • September 5, 2024

For Weight Loss (Obesity/Overweight) "I struggled with weight a majority of my life, I lost weight naturally in the past, but since then my body has undergone a lot of stress from my life that this time around I found it very difficult. I started at 215 and managed to get down to 174, but then I ended up gaining some of it back, which put me back up to 195. I got put on phentermine at 37.5 mg, and I have been taking it for a little over a week and have already lost 11 pounds, it has curbed my appetite and some cravings. I also drink about 80 ounces of water daily and eat as healthy as I can. I'm currently sitting at 184 pounds, and my short goal is 160. I'm feeling very hopeful."

10 / 10
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13 Report

Frequently asked questions

  • Mom...
  • Taken for 1 to 6 months
  • June 6, 2019

For Weight Loss (Obesity/Overweight) "I am 30 years old and a mom of four. I just finished my first month of phentermine. I am 5'4" and began at 171 lbs. So far, I have lost 17 pounds. The side effects I feel are dry mouth (I drink water all day), loss of appetite, and a boost of energy. With the dry mouth, I mostly feel it at the back of my throat. Not only is my appetite suppressed, but I don't crave sweets. I was a Pepsi drinker, Pepsi was my water, and I have barely had pop since I started this-maybe five times-and I can't even drink a whole can. I have not changed my diet, which includes lots of carbs. I eat one small meal a day. I do not work out either. I'll post another update after I finish my second month."

10 / 10
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63 Report
  • Lis...
  • February 17, 2021

For Weight Loss (Obesity/Overweight) "I started taking this medication on 1/11/21, weighed in at 246 pounds. On 1/27/2021, I weighed in at 237 pounds. Today, 2/17/2021, I’m 224 pounds. I have no appetite, and I work out 5 times a week for 1 hour. My goal is 190 pounds. The first few days, I felt weird, after that, no symptoms. I can barely eat a medium-sized chicken drumstick. I know I’m averaging less than 1200 calories per day."

10 / 10
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  • Anonymous
  • January 25, 2010

Phentermine for Weight Loss (Obesity/Overweight) "I started taking Adipex on November 17, 2009. It is now January 25, 2010. I have to admit when I first started taking Adipex, I felt like I was on straight speed. I couldn't sleep, eat, or concentrate. I still have bad mood swings and get upset very easily. I have no problem sleeping, that wore off the 3rd week. I tend to get hungry later in the afternoon. I was taking a half of a pill the first month. I take one pill a day now and do great, except for my mood swings. My starting weight was 165 lbs. I now weigh 138 lbs. That's a weight loss of 27 lbs. I still have 8 lbs to go. I exercise 5 days a week on the treadmill for 30 minutes each time. If you are really wanting to lose weight and can overlook the side effects, this is the pill! Good Luck!"

10 / 10
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102 Report
  • Sky...
  • Taken for less than 1 month
  • September 13, 2022

For Weight Loss (Obesity/Overweight) "So I started taking phentermine on 9/10/22. I weighed myself on an empty stomach at 284 lbs. I weighed myself today on an empty stomach, 9/12/22, and no joke, I weighed 269.6. I’ve been taking 1200-1500 calories daily, cut out soda, and at work, I do walk a lot, about 7 miles a day. But, energy is through the roof, decreased hunger, I feel 20 years younger already. I love it. Also, I have generalized anxiety disorder, and it didn’t affect that or my medication (Lexapro), so that’s a huge plus."

10 / 10
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  • lor...
  • May 29, 2014

For Weight Loss (Obesity/Overweight) "I started phentermine on May 1st, 2014. I lost 9 pounds in the first week. It's hard to eat, I'm never hungry, so I need to start eating something healthy and small a few times a day. I have missed 5 pills this month, but now on May 29th, I'm down 13 pounds. My starting weight was 189, and now I'm at 176. I'm hoping it will continue to drop, I'd like to be at 150."

8 / 10
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75 Report
  • Kar...
  • Taken for 1 to 6 months
  • December 20, 2013

For Weight Loss (Obesity/Overweight) "I started taking phentermine 2 1/2 months ago. Thinking I weighed around 250 lbs, I decided to go to a weight loss clinic. At my 1st appointment, I couldn't believe I actually weighed 336 lbs. I am 5'4" and 24 years old. I go to the clinic every Saturday to get weighed, get a B12 shot, and also they give me my medicines for 1 week. The phentermine, amino acids, calcium, and a multivitamin. So after 10 weeks of a strict protein diet and at least 2 hours in the gym every day, I am now down to 269 lbs. That's 68 pounds in 2 1/2 months. I wouldn't be able to stick to my diet without the phentermine. It definitely suppresses my appetite."

10 / 10
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79 Report
  • Dee...
  • Taken for less than 1 month
  • May 4, 2021

For Weight Loss (Obesity/Overweight) "I’m 260, 5’11. I’m 55, biggest I’ve ever been. I started taking phentermine yesterday, May 3, 2021. It made me have energy this morning when I took it, I wasn’t hungry. I had yogurt for breakfast and a stuffed bell pepper for lunch. I want to get down to 198 pounds, I’m hoping by October because I don’t want to take any longer than that."

9 / 10
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38 Report
  • CC2...
  • August 26, 2016

For Weight Loss (Obesity/Overweight) "I use only 15 mg (doc prescribed 30, but I could not sleep at all with 30 mg, also, it was so strong I did not have an appetite at all, and I would take only 300 calories per day, if that much). So 15 mg works for me. I count calories, I do not go over 1400 per day, I run/walk 30 minutes per day, drink one gallon of water, and eat everything in small portions like 5x per day. My snack is apples or almonds, but I also eat a sandwich once in a while or spaghetti or rice. The only thing I do not consume is chocolate or any other sweets. My carbs come from fruit or baked potatoes or corn... I went from 246.5 to 229 since August 1 (so in 25 days, almost 18 lbs). I will probably lose a few more until Monday, so I think a total of 20 lbs per month is great."

10 / 10
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  • Ste...
  • February 21, 2019

For Weight Loss (Obesity/Overweight) "I work overnight, and I've struggled to lose weight due to eating right after work and before I go to sleep. I used to work out and have never had a problem doing so, but working long hours and having 2 kids, all I wanted to do was sleep when I could. My motivation was seeing a pic of me on a family vacation right before Christmas and just seeing how swollen I looked. I started taking phentermine 37.5 on January 10, 2019, weighing in at 190 lbs. I am 5'4'', 36 years old, and today, February 21, 2019, I am down to 177 lbs. No exercise, only better eating habits. When I get off work, I only drink a smoothie for breakfast. When I wake up, I eat a salad. I don't starve myself, but this pill suppresses your appetite big time! I drink water every day. It makes you more aware of what you eat. I lost 12 lbs in exactly 1 month, and I'm hoping to be at 166 by March 10... my goal is 150 by April. I will post back on that day with my results. Good luck to everyone!"

10 / 10
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40 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • July 4, 2015

For Weight Loss (Obesity/Overweight) "I just want to say I did NOT exercise on Phentermine. And after trying NUMEROUS, and I mean NUMEROUS weight loss medications, Phentermine did help me lose 60 lbs! I started off at 200 lbs back in August of 2014, when I asked my doctor for it. Right away, it took my appetite away and I stopped drinking soda (which was my #1 bad habit). That's when I finally started drinking water (which I NEVER did) and since then, I've started gradually eating smaller portions. Month by month, I hit plateaus, but went past those. I averaged 4-5 lbs a week. I lost a total of 60 lbs. I am now 130 lbs! It is now 7/4/15, and I have been off Phentermine for 4 months and have kept the weight off and have not gained a pound! It has helped me."

10 / 10
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59 Report
  • Sli...
  • Taken for less than 1 month
  • October 26, 2015

Phentermine for Weight Loss (Obesity/Overweight) "Oct. 16th - 5'8, 256 lbs, Male. Oct. 26th - 240 lbs even. 16 lbs - 10 days. Loss of appetite, which makes it easy to control how, what, and when you eat. Dry mouth only if you don't drink lots of water, which is absolutely necessary to dispose of the fat you're losing. 1/2 pill - modest energy. Whole pill - a bit shaky, but I love shaky. Feels like a miracle is happening. Getting my life back slowly but surely."

9 / 10
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55 Report
  • can...
  • Taken for 1 to 2 years
  • February 21, 2013

Phentermine for Weight Loss (Obesity/Overweight) "I have been on Adipex for almost two years. When they say it's not such a thing as a miracle pill, they haven't tried this. I lost 10 pounds from my goal of losing 150 pounds. My weight loss has slowed down a bit, but as long as the numbers go down and not up, I'm still happy. I did experience extremely dry mouth, dizziness, and loss of appetite for the first two months. BUT IT WAS WORTH EVERY BIT. Now I'm starting to have sleeping problems, which I don't like. I am very scared that if I stop taking it, I'm going to gain my weight back."

10 / 10
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65 Report
  • DDa...
  • May 9, 2021

For Weight Loss (Obesity/Overweight) "I took Adipex from late spring of 2015, starting at around 181 lbs. That July, I got down to 148 lbs. In July 2017, I gave birth to my daughter and waited until I was 4 months PP before taking it again. When I started taking it this time, I was at 192 lbs. From November 2017 to July 2018, I got all the way down to 131 lbs. Needless to say, it did help me lose weight. Absolutely! At first, the weight dropped off on its own. Try not to rely on the pill itself to drop the weight. That’s when it becomes addicting. You have to be extremely mindful of what you eat and drink water. It’s that important, I promise. I noticed in February and March of this year that the pill didn’t feel the same. My appetite was suppressed, but so was my energy. It’s great that I wasn’t eating my emotions anymore, but I wasn’t losing weight because I wasn’t moving my body. It sounds like the change that was made recently could have been why. I ended up changing manufacturers because of this."

8 / 10
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27 Report
  • Ban...
  • May 25, 2020

Phentermine for Weight Loss (Obesity/Overweight) "I do have ADD, and this is a low-grade amphetamine, so for someone who doesn’t have ADD, these may work. I am not sure why my doctor chose to put me on these, as they do the complete opposite for me. Since I do have ADD, they stabilize me rather than stimulate. The side effects include insomnia, high BP, lower appetite, and boost energy. I am not a person who naps, I can run on 5 hours of sleep, and these made me SO TIRED after taking them. They didn’t give me high BP, they didn’t cause insomnia, they didn’t give me energy, and they did not lower my appetite. They did give me brain fog. You’re apparently supposed to lose 2 lbs per week on these pills. My doctor had me on one 8 mg tablet, then wanted to bump it up to one and a half. I did not continue the meds because even after a month, change in diet, and consistent working out and walking, they still did nothing for me. I started these at 226 and have actually been fluctuating between 237-230 since taking them. I do not recommend."

1 / 10
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59 Report
  • Kik...
  • Taken for less than 1 month
  • May 25, 2017

For Weight Loss (Obesity/Overweight) "I'm 5'2", 32 years old and had been an athlete most of my years (track and field sprinter, powerlifter, and basketball), always weighing between 114-130. I went through a depression and gained 40 lbs within 6 months last year. I went to my doctor for weight loss help (after getting my depression under control), and she prescribed me Adipex-P (phentermine 37.5). I take the whole pill. On May 10, my weight was 174 lbs, May 16: 166 lbs, May 25: 163 lbs. I'm very happy and encouraged to keep it going. I run 1.2 miles 2-3 times a week. My goal is to drop 20 lbs by my next doctor appointment on June 20, 2017, and my overall goal is to be 125-130 lbs. Side effects: no appetite, dry mouth. I will update this every month as I progress."

10 / 10
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  • msp...
  • August 26, 2008

Phentermine for Weight Loss (Obesity/Overweight) "I started taking Adipex-P on August 15, 2008. I weighed 177 lbs. It's been a little over a week, and I can tell that I've lost weight. I haven't weighed myself again, but I can tell by the way my clothes fit. My appetite has changed since I began taking the pill. I will weigh myself next month on the 15th to see how much I've lost. I highly recommend this pill to anyone who wants to lose weight."

9 / 10
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66 Report
  • CCa...
  • Taken for 1 to 6 months
  • August 2, 2019

For Weight Loss (Obesity/Overweight) "I started taking Phentermine on 6/28/19. I went in today, 8/2/19, and I have lost 25 lbs! The day I started taking it, I gave up soda and sweets for good. I drink nothing but water. I eat anywhere from 800-1,000 calories per day. I haven’t even begun to exercise yet, but I plan on starting that today by walking 2 miles per day. Phentermine helps suppress my appetite immensely and gives me an energy boost, which is great for doing the things I do around my house daily."

10 / 10
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  • Ros...
  • October 17, 2016

Phentermine for Weight Loss (Obesity/Overweight) "I am 5'4" and 178 lbs. I started taking Adipex 37.5 on 10/15/16. Today is my third pill. I have no appetite, I had to force myself to eat yesterday. I can't sleep, and I feel lightheaded. I got on the scale this morning, my weight was 175. My goal is 140. I will be updating my progress every week."

5 / 10
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36 Report
  • Tru...
  • Taken for less than 1 month
  • April 28, 2017

Phentermine for Weight Loss (Obesity/Overweight) "Started taking 12 days ago, starting weight of 256.6 lb & today 250.0 lb. Side effects: increased energy which I absolutely love, suppressed appetite which is good, dry mouth which means I drink a lot of water which also is good. Considering I struggled with drinking enough water daily, this changed that. I still get hungry, but only 2-3 times a day, once I start to eat, I'm full very quickly. A simple snack like fruit or raw veggies quickly takes the hunger away. I eat a sensible dinner with the family. I've completely lost interest in soda & sweets. I do take a multivitamin. Stay smart, watch what you know you should be eating, exercise & live healthy. You can do it, this helps."

10 / 10
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30 Report
  • Sar...
  • April 19, 2017

For Weight Loss (Obesity/Overweight) "I took Phentermine in November and December of 2013 and January of 2014. I went from 178 pounds to 137. 137 is my target weight and ideal weight. I kept the weight off until this past spring/summer (2016). And then went back to my old habits and managed to gain enough weight to put me at 176.2 as of this morning at the doctor. So, I'm 50 years old, 5'6" and weigh 176.2. I started the Phentermine right after the doctor's appointment. I'm a little bit jittery today, loss of appetite is already taking effect, as has dry mouth. I go back to the doctor in 30 days, but I will weigh myself on Wednesdays."

10 / 10
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31 Report
  • bon...
  • Taken for 1 to 6 months
  • April 12, 2019

For Weight Loss (Obesity/Overweight) "I lost 48 pounds on phentermine from September 2016 to January 2017. I noticed that the yellow phentermine worked better than the blue ones. Anyone have any experience with that? I definitely had no appetite, and I was on a no-carb diet. I drank a lot of water."

9 / 10
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23 Report
  • Len...
  • Taken for 1 to 6 months
  • June 21, 2019

For Weight Loss (Obesity/Overweight) "I have been taking phentermine for 2 1/2 months. It's not a magic pill. I started at 145 pounds and now I am down to 132. It does suppress your appetite, but you have to watch what you eat. I work out 5 days a week."

5 / 10
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23 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.