Comparing Contrave vs Phentermine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Contrave bupropion / naltrexone

Phentermine

Prescribed for Weight Loss, Obesity. Contrave may also be used for purposes not listed in this medication guide.

Phentermine may be used short-term as an aid to weight loss; however, it can be addictive and tolerance may develop to its weight-losing effects, rendering it less effective with time. Prescribed for... View more

Prescription only

Ratings & Reviews

View all 1906 reviews

View all 2894 reviews

Drug Class

Anorexiants

Side Effects

Common side effects include: constipation, dizziness, headache, insomnia, nausea, and vomiting.

See the full Contrave side effects document.

See the full phentermine side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	70 tablet, extended release
Dosage	90 mg-8 mg
Per Unit^*	$3.68
Cost^*	$257.89

View all Contrave prices

Quantity	7 tablet
Dosage	37.5 mg
Per Unit^*	$1.82
Cost^*	$12.73

View all phentermine prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Oral tablet, extended release

Oral capsule
Oral tablet

Brand Names

N/A

Adipex-P, Atti-Plex P, Lomaira

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

21 hours

20 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.

Pregnancy Category

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

Category X Not for use in pregnancy

See the full Pregnancy Warnings document.

Drug Interactions

A total of 638 drugs are known to interact with Contrave:

214 major drug interactions (928 brand and generic names)
419 moderate drug interactions (1863 brand and generic names)
5 minor drug interactions (16 brand and generic names)

A total of 170 drugs are known to interact with phentermine:

42 major drug interactions (183 brand and generic names)
126 moderate drug interactions (572 brand and generic names)
2 minor drug interactions (5 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures... View more

Using phentermine with alcohol can increase the risk of cardiovascular side effects such as... View more

Disease Interactions

First Approval Date

September 10, 2014

August 14, 1973

WADA Class

View World Anti-Doping Agency classifications.

N/A

S6 - Stimulants

More Information

Consumer Resources

Advanced Reading

Professional Resources

Prescribing Information

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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