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Comparing Oxycodone vs Tramadol

Oxycodone

Tramadol

Oxycodone is a potent pain-relieving medicine which should be reserved for mainly cancer-related pain. It carries a high potential for addiction and common side effects include sedation and... more

Tramadol is a strong pain relief medicine effective for both general and nerve-related pain. Tramadol can cause dependence and use may be limited by side effects such as nausea and... more

Prescription only

Prescription only

Ratings & Reviews

Recent helpful reviews
8.3
752 Reviews

For Pain Have been on oxycodone 30 mg for about 4 years,have DDD and anular radial tear.. Basically my back is wrecked.. Tried all other types of meds but none made my life worth living again like the oxycodone.. Although I'm prescribed 5 a day I find some days don't need all 5..wish ppl would not abuse meds because have made it hard for the ones who do!

9
Big Dave 19

For Pain Intense chronic back pain! Only relief I can find is from this medication.

9
cardiackid63
6.8
1307 Reviews

For Pain I was prescribed Tramadol by an emergency room doctor until I can get in to get my wisdom teeth removed. I'm supposed to take one pill every six hours, but only take one pill whenever I have absolutely unbearable pain, that doesn't go away within one hour. The pain relief is quick, within 20 minutes, takes from a 10 on the pain scale to about 5. Terrible nausea, shakes, lightheadedness, and sweats if I don't eat plenty before or right after taking this medication. Constipation also caused, clears up two or three days after ceasing.

6
fifthwheelfantasy

For Pain Tramadol would MILDLY work for my back and knee pain for about a week and then stop. Oxycodone works best for me and hydrocodone is second. If it works for your pain, great but my experience is that it does nothing more than ibuprofen or other OTC pain relievers in the long run. The physical withdrawal from tramadol in my opinion is worse than hydrocodone or oxycodone due to the dual action it has on the brain.

6
jeeperinva

View all 752 reviews

View all 1307 reviews

Drug Class

Side Effects

Commonly reported side effects include: constipation, drowsiness, nausea, pruritus, and vomiting.

See the full oxycodone side effects document.

Commonly reported side effects include: pruritus, agitation, anxiety, constipation, diarrhea, hallucination, nausea, tremor, vomiting, and diaphoresis.

See the full tramadol side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 6 tablet
Dosage 5 mg
Per Unit* $1.64 - $1.72
Cost* $9.86 - $10.30
View all oxycodone prices
Quantity 6 tablet
Dosage 50 mg
Per Unit* $1.76
Cost* $10.54
View all tramadol prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Oral capsule
  • Oral concentrate
  • Oral solution
  • Oral tablet
  • Oral tablet, extended release
  • Oral capsule, extended release
  • Oral tablet
  • Oral tablet, extended release

Brand Names
Dazidox, Endocodone, ETH-Oxydose, M-Oxy, Oxaydo, OxyContin, Oxydose, Oxyfast, OxyIR, Percolone, Roxicodone, Roxicodone Intensol, RoxyBond, Xtampza ER more... ConZip, Tramadol Hydrochloride ER, Ultram

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

5.6 hours

5.2 hours

CSA Schedule**

View glossary of terms.
2
High potential for abuse

Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
4
Some potential for abuse

Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.

Pregnancy Category
N
Category N Not classified

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (1)

FDA Alerts (3)

Drug Interactions

A total of 951 drugs are known to interact with oxycodone:

  • 340 major drug interactions (1720 brand and generic names)
  • 609 moderate drug interactions (3666 brand and generic names)
  • 2 minor drug interactions (6 brand and generic names)

A total of 946 drugs are known to interact with tramadol:

  • 491 major drug interactions (2341 brand and generic names)
  • 447 moderate drug interactions (2770 brand and generic names)
  • 8 minor drug interactions (42 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Do not use alcohol or medications that contain alcohol while you are receiving treatment with... more
  • Alcohol can increase the nervous system side effects of traMADol such as dizziness, drowsiness, and... more

Disease Interactions

First Approval Date

October 26, 1998

March 03, 1995

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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