Comparing Oxycodone vs Tramadol
| Oxycodone Remove Oxycodone from your drug comparison | Tramadol Remove Tramadol from your drug comparison |
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Oxycodone is a potent pain-relieving medicine that should be reserved for mainly cancer-related pain. It carries a high potential for addiction and common side effects include sedation and... View more |
Tramadol is a strong pain relief medicine effective for both general and nerve-related pain. Tramadol can cause dependence and use may be limited by side effects such as nausea and... View more |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: constipation, drowsiness, nausea, pruritus, and vomiting. See the full oxycodone side effects document. |
Commonly reported side effects include: pruritus, agitation, anxiety, constipation, diarrhea, hallucination, nausea, tremor, vomiting, and diaphoresis. See the full tramadol side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all oxycodone prices |
View all tramadol prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Dazidox, Endocodone, ETH-Oxydose, Oxaydo, OxyContin, Oxydose, Oxyfast, Roxicodone, Xtampza ER View more | ConZip, Qdolo, Tramadol Hydrochloride ER, Ultram | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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5.6 hours |
5.2 hours |
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CSA Schedule**View glossary of terms. |
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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Pregnancy Category |
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Category N
Not classified
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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FDA Alerts |
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Drug Interactions |
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A total of 531 drugs are known to interact with oxycodone:
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A total of 541 drugs are known to interact with tramadol:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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October 26, 1998 |
March 03, 1995 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.