Comparing Methadone vs Tramadol
Methadone | Tramadol |
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Methadone | Tramadol |
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Prescription only
Methadone is a potent opioid analgesic that may be used to relieve severe pain unresponsive to other strong pain relievers; however, it is more commonly used to treat opioid addiction. There is a... View more |
Prescription only
Tramadol is a strong opioid pain relieving medication that may be used to treat moderate to severe general and nerve-related pain. Tramadol may be habit-forming and misuse can cause addiction... View more |
Related suggestions Chronic Pain
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More about Methadone | More about Tramadol | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Methadone has an average rating of 8.7 out of 10 from a total of 607 ratings on Drugs.com. 84% of reviewers reported a positive effect, while 6% reported a negative effect. |
Tramadol has an average rating of 7.0 out of 10 from a total of 1884 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 23% reported a negative effect. |
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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Methadone side effects |
View all Tramadol side effects |
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Drug Class | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Methadone prices |
View all Tramadol prices |
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Dosage Forms | |||||||||||||||||
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Brand Names | |||||||||||||||||
Methadone Diskets, Methadose, Methadose Sugar-Free | ConZip, Qdolo, Tramadol Hydrochloride ER | ||||||||||||||||
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
30 hours |
5.2 hours |
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CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 838 drugs are known to interact with Methadone:
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A total of 713 drugs are known to interact with Tramadol:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
August 13, 1947 |
March 03, 1995 |
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WADA Class View classifications | |||||||||||||||||
More Information | |||||||||||||||||
Patient Resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.