Makena Alternatives Compared
| Makena (hydroxyprogesterone) | Nifedipine | Progesterone |
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| Makena (hydroxyprogesterone) | Nifedipine | Progesterone |
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Prescription only
Prescribed for Premature Labor. Makena may also be used for purposes not listed in this medication guide. |
Prescription only
Nifedipine is used in the treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to other treatments. It should not be used to rapidly drop blood pressure as this... View more |
Prescription and OTC
Progesterone is a hormone that is used to treat conditions associated with ovulation, fertility, menstruation, menopause, or abnormal uterine bleeding. It may be used in gender-affirming therapy to... View more |
Related suggestions Premature Labor
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| More about Makena (hydroxyprogesterone) | More about Nifedipine | More about Progesterone | ||||||||
| Ratings & Reviews | ||||||||||
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Makena has an average rating of 6.9 out of 10 from a total of 153 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 22% reported a negative effect. |
Nifedipine has an average rating of 5.0 out of 10 from a total of 164 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 43% reported a negative effect. |
Progesterone has an average rating of 6.5 out of 10 from a total of 78 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||
View all Makena side effects |
View all Nifedipine side effects |
View all Progesterone side effects |
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| Drug Class | ||||||||||
| Generic Availability | ||||||||||
| Lower cost generic approved |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Progesterone prices |
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| Dosage Forms | ||||||||||
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| Brand Names | ||||||||||
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N/A |
Afeditab CR, Procardia, Procardia XL | Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa, Prometrium | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||
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N/A |
5 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||
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A total of 232 drugs are known to interact with Makena:
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A total of 631 drugs are known to interact with Nifedipine:
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A total of 219 drugs are known to interact with Progesterone:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||
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| Disease Interactions | ||||||||||
| First Approval Date | ||||||||||
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N/A |
December 31, 1981 |
November 01, 1974 |
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| WADA Class View classifications | ||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||
| Patient Resources | ||||||||||
| Professional Resources | ||||||||||
| Related Treatment Guide | ||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Prometrium
Prometrium is a female hormone used to cause menstrual periods in women who have not yet reached ...
Endometrin
Endometrin is used in fertility treatment for women with low levels of natural progesterone ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Crinone
Crinone is used for amenorrhea, endometrial hyperplasia, prophylaxis, perimenopausal symptoms ...
Brethine
Brethine is used for asthma, acute, asthma, maintenance, premature labor
Terbutaline
Terbutaline is used for allergic asthma, asthma, acute, asthma, maintenance, premature labor
Progesterone
Progesterone is a female hormone important for the regulation of ovulation and menstruation ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.