Makena Alternatives Compared
| Makena (hydroxyprogesterone) | Nifedipine | Progesterone |
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| Makena (hydroxyprogesterone) | Nifedipine | Progesterone |
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Prescription only
Prescribed for Premature Labor. Makena may also be used for purposes not listed in this medication guide. |
Prescription only
Nifedipine is used in the treatment of vasospastic angina and occasionally for chronic unstable angina as an add-on to other treatments. It should not be used to rapidly drop blood pressure as this... View more |
Prescription and OTC
Progesterone is a hormone that is used to treat conditions associated with ovulation, fertility, menstruation, menopause, or abnormal uterine bleeding. It may be used in gender-affirming therapy to... View more |
Related suggestions Premature Labor
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| More about Makena (hydroxyprogesterone) | More about Nifedipine | More about Progesterone | ||||||||
| Ratings & Reviews | ||||||||||
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Makena has an average rating of 6.9 out of 10 from a total of 153 ratings on Drugs.com. 57% of reviewers reported a positive effect, while 22% reported a negative effect. |
Nifedipine has an average rating of 5.0 out of 10 from a total of 164 ratings on Drugs.com. 34% of reviewers reported a positive effect, while 43% reported a negative effect. |
Progesterone has an average rating of 6.5 out of 10 from a total of 78 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||
View all Makena side effects |
View all Nifedipine side effects |
View all Progesterone side effects |
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| Drug Class | ||||||||||
| Generic Availability | ||||||||||
| Lower cost generic approved |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Progesterone prices |
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| Dosage Forms | ||||||||||
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| Brand Names | ||||||||||
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N/A |
Afeditab CR, Procardia, Procardia XL | Crinone, Cyclogest, Endometrin, First Progesterone MC10, First Progesterone MC5, Gestone, Milprosa, Prometrium | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||
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N/A |
5 hours |
1 hour |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category B
No proven risk in humans
Oral Formulations
Category N
Not classified
Excluding Oral Formulations See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||
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A total of 234 drugs are known to interact with Makena:
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A total of 631 drugs are known to interact with Nifedipine:
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A total of 221 drugs are known to interact with Progesterone:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||
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| Disease Interactions | ||||||||||
| First Approval Date | ||||||||||
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N/A |
December 31, 1981 |
November 01, 1974 |
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| WADA Class View classifications | ||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||
| Patient Resources | ||||||||||
| Professional Resources | ||||||||||
| Related Treatment Guide | ||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.