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Makena (hydroxyprogesterone) Drug Interactions

A total of 344 drugs are known to interact with Makena (hydroxyprogesterone).

  • 327 moderate drug interactions
  • 17 minor drug interactions

Show all medications in the database that may interact with Makena (hydroxyprogesterone).

Check for interactions

Type in a drug name to check for interactions with Makena (hydroxyprogesterone).

Most frequently checked interactions

View interaction reports for Makena (hydroxyprogesterone) and the medicines listed below.

  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Bufferin, Fasprin, Arthritis Pain, Easprin, Aspergum, Aspiritab, Halfprin, Empirin, Ascriptin Enteric, Aspirin Lite Coat, Aspi-Cor, Aspirtab, Ecotrin Adult Low Strength, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Entercote, St. Joseph Aspirin, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Bayer Aspirin Regimen, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Avastin (bevacizumab)
  • Botox (onabotulinumtoxinA)
  • Celestone Phosphate (betamethasone)
  • Colace (docusate)
  • dexamethasone (Decadron, Dexamethasone Intensol, Dexasone, Decadron Phosphate, Injectable, Hexadrol, TaperDex, Baycadron, Dexpak Taperpak, Dalalone, Dexacort Phosphate in Respihaler, De-Sone LA, Dexone, Dexone LA, ZoDex, Medidex, Zonacort, LoCort, Adrenocot LA, Dalalone DP, Dalalone LA, HiDex, Decaject, Decaject LA, Zema Pak, Dxevo, Decadron-LA, Solurex LA, Dexacen-4, Solurex, Adrenocot, Dexacort-LA, Dexasone LA, Primethasone, Dexacorten, Medidex LA)
  • diphenhydramine (Benadryl, Banophen, Benadryl Allergy, ZzzQuil, Sleep, Unisom SleepGels, Benadryl Children's Allergy, Sominex, Dicopanol, Diphen, Sleep Tabs, Simply Sleep, Diphedryl, Diphenadryl, Quenalin, Diphenyl, Hydramine, Diphenydramine Quick Melt, Unisom SleepMelts, Nytol, Dormin, Sleepwell 2-nite, Diphenhist, 40 Winks, Diphen Cough, DPH, Calm-Aid, Sleep Tab II, Altaryl, Snooze Fast, Sominex Maximum Strength Caplet, Unisom SleepMinis, Unisom Liquid, Triaminic Thin Strips Allergy, ConRx Allergy, Buckley's Bedtime, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphen AF, Aler-Dryl, Allergia-C, Benahist-10, Benahist-50, Benoject-50, Genahist, Alka-Seltzer Plus Allergy, Q-Dryl, Aller-G-Time, Sleep-Eze-3, Somnicaps, Nytol QuickCaps, Total Allergy, Trux-adryl, Valu-Dryl, Triaminic Thin Strips Cough & Runny Nose, Beldin, Belix, Vicks QlearQuil Nighttime Allergy Relief, Siladryl, Siladryl DAS, Siladyl SA, Silphen Cough, Sleep-ettes, Tusstat, Diphenylin, Hydramine Compound, Pardryl, Nervine, Nu-Med, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Allermax, Diphendryl, Twilite, Banaril, Aler-Tab, Siladryl Allergy, Theraflu Thin Strips Multi Symptom, Sleep-ettes D, Uni-Tann, Q-Dryl A/F, Diphenmax, Nightime Sleepaid, Ben-Tann, Dytan, Vanamine PD, Pharbedryl, Histaprin, Z-Sleep, Tranquil Nighttime Sleep Aid, PediaCare Children's Allergy, Truxadryl, Complete Allergy Relief, Dytuss, Miles Nervine, Scot-Tussin Allergy)
  • Euflexxa (sodium hyaluronate)
  • fluorouracil (Adrucil)
  • goserelin (Zoladex, Zoladex 3-Month)
  • Imitrex (sumatriptan)
  • Neulasta (pegfilgrastim)
  • nifedipine (Procardia, Adalat, Nifedical XL, Procardia XL, Nifediac CC, Adalat CC, Afeditab CR)
  • PNV Prenatal Plus (multivitamin, prenatal)
  • progesterone (Prometrium, Crinone, Endometrin, Progest, Cyclogest, Menopause Formula Progesterone, First Progesterone MC10, First Progesterone MC5, Gestone, Prochieve)
  • Remicade (infliximab)
  • Supartz (sodium hyaluronate)
  • Taxol (paclitaxel)
  • Triveen Ten (multivitamin, prenatal)
  • Tylenol (acetaminophen)

Makena (hydroxyprogesterone) alcohol/food interactions

There are 6 alcohol/food interactions with Makena (hydroxyprogesterone)

Makena (hydroxyprogesterone) disease interactions

There are 10 disease interactions with Makena (hydroxyprogesterone) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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