Comparing Lupron Depot vs Orilissa
| Lupron Depot | Orilissa |
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| Lupron Depot (leuprolide) | Orilissa (elagolix) |
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Prescription only
Lupron Depot is a hormone deprivation treatment that may be used for the palliative care of advanced prostate cancer. The main side effects are hot flashes and general pain and it may cause... View more |
Prescription only
Prescribed for Endometriosis. Orilissa may also be used for purposes not listed in this medication guide. |
Related suggestions |
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| More about Lupron Depot (leuprolide) | More about Orilissa (elagolix) | ||||||||||||||||
| Generic Status | |||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | |||||||||||||||||
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Lupron Depot has an average rating of 5.7 out of 10 from a total of 215 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 34% reported a negative effect. |
Orilissa has an average rating of 5.3 out of 10 from a total of 124 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 41% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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See also: Lupron Depot side effects in more detail. |
See also: Orilissa side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lupron Depot prices and generic prices |
View all Orilissa prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other leuprolide brands include: Camcevi, Eligard, Fensolvi, Lupron Depot-PED |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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4.25 hours |
6 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 275 drugs are known to interact with Lupron Depot:
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A total of 347 drugs are known to interact with Orilissa:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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January 26, 1989 |
July 23, 2018 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.