Comparing Hydroxychloroquine vs Malarone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Hydroxychloroquine	Malarone (atovaquone / proguanil)	Enter another drug to compare

Hydroxychloroquine

Malarone (atovaquone / proguanil)

Prescription only

Prescribed for Rheumatoid Arthritis, Lupus, Lyme Disease - Arthritis, Lichen Planopilaris, Dermatomyositis, Malaria Prevention, Malaria, Sjogren's Syndrome, Undifferentiated Connective Tissue... View more

Prescription only

Prescribed for Malaria Prevention, Malaria. Malarone may also be used for purposes not listed in this medication guide.

More about Hydroxychloroquine

More about Malarone (atovaquone / proguanil)

Ratings & Reviews

Hydroxychloroquine has an average rating of 6.4 out of 10 from a total of 356 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 29% reported a negative effect.

Malarone has an average rating of 5.5 out of 10 from a total of 45 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 40% reported a negative effect.

View all 356 reviews

View all 45 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Nausea (11.8%)
Rash (9.3%)
Pain (7.9%)
Fatigue (6.7%)
Headaches (6.7%)
Hair loss (5.6%)
Upset stomach (5.1%)

View all Hydroxychloroquine side effects

View all Malarone side effects

Drug Class

Antimalarial combinations

Generic Availability

Lower cost generic

Lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	50 each
Strength	200 mg
Per unit^*	$1.26 - $1.48
Cost^*	$63.03 - $74.19

View all Hydroxychloroquine prices

Quantity	24 tablet
Strength	250 mg-100 mg
Per unit^*	$7.75
Cost^*	$185.93

View all Malarone prices

Get free Discount Card

Dosage Forms

Oral tablet

Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

N/A

60.5 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category N Not classified

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 585 drugs are known to interact with Hydroxychloroquine:

224 major drug interactions (717 brand and generic names)
345 moderate drug interactions (1287 brand and generic names)
16 minor drug interactions (50 brand and generic names)

A total of 124 drugs are known to interact with Malarone:

13 major drug interactions (27 brand and generic names)
104 moderate drug interactions (584 brand and generic names)
7 minor drug interactions (21 brand and generic names)

Alcohol/Food/Lifestyle Interactions

You may want to limit your consumption of grapefruit or grapefruit juice during treatment with... View more

Food significantly enhances the absorption of atovaquone. You should take each dose of atovaquone... View more

Disease Interactions

First Approval Date

N/A

July 14, 2000

WADA Class View classifications

N/A

More Information

Patient Resources

Hydroxychloroquine uses

Malarone uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Hydroxychloroquine vs Malarone

See also:

Humira

Plaquenil

Benlysta

Rocephin

Decadron

Enbrel

Remicade

Amoxil

Dexamethasone Intensol

Imuran

Further information

Comparing Hydroxychloroquine vs Malarone

See also:

Further information

Compare Drugs