Hydrocortisone Alternatives Compared
| Hydrocortisone Remove Hydrocortisone from your drug comparison | Prednisone Remove Prednisone from your drug comparison | Cortef Remove Cortef from your drug comparison |
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| Hydrocortisone Remove Hydrocortisone from your drug comparison | Prednisone Remove Prednisone from your drug comparison | Cortef hydrocortisone Remove Cortef from your drug comparison |
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Prescribed for Adrenocortical Insufficiency, Addison's Disease, Asthma - acute, Crohn's Disease - Acute, Inflammatory Bowel Disease, Inflammatory Conditions, Ulcerative Proctitis, Shock, Ulcerative... View more |
Prednisone effectively controls inflammation and an overactive immune system but may not be suitable for everybody. Long-term use is limited by potentially severe side effects such as adrenal... View more |
Prescribed for Adrenocortical Insufficiency, Addison's Disease, Asthma - acute, Crohn's Disease - Acute, Inflammatory Bowel Disease, Inflammatory Conditions, Ulcerative Proctitis, Shock, Ulcerative... View more |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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See the full hydrocortisone side effects document. |
See the full prednisone side effects document. |
See the full Cortef side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all hydrocortisone prices |
View all prednisone prices |
View all Cortef prices and generic prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Alkindi Sprinkle, Cortef, Cortenema, Cortifoam, Solu-Cortef | Rayos | Other hydrocortisone brands include: Alkindi Sprinkle, Cortenema, Cortifoam, Solu-Cortef | ||||||||||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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12 hours |
36 hours |
12 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
Excluding First Trimester
Category D
Positive evidence of risk
First Trimester See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 529 drugs are known to interact with hydrocortisone:
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A total of 516 drugs are known to interact with prednisone:
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A total of 529 drugs are known to interact with Cortef:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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August 05, 1952 |
February 21, 1955 |
December 15, 1952 |
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WADA ClassView World Anti-Doping Agency classifications. |
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More Information |
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Patient resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.