Comparing Dexamethasone vs Hydrocortisone
Dexamethasone | Hydrocortisone |
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Dexamethasone | Hydrocortisone |
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Prescription only
Dexamethasone reduces inflammation and calms down an overactive immune system and is significantly more potent than prednisolone. It may be given to control inflammation associated with eye disease... View more |
Prescription only
Prescribed for Adrenocortical Insufficiency, Addison's Disease, Asthma - acute, Crohn's Disease - Active, Ulcerative Proctitis, Inflammatory Bowel Disease, Inflammatory Conditions, Shock, Ulcerative... View more |
Related suggestions Inflammatory Conditions
Ulcerative Colitis
Asthma, acute
Inflammatory Bowel Disease
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More about Dexamethasone | More about Hydrocortisone | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Dexamethasone has an average rating of 6.0 out of 10 from a total of 161 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 34% reported a negative effect. |
Hydrocortisone has an average rating of 7.7 out of 10 from a total of 30 ratings on Drugs.com. 74% of reviewers reported a positive effect, while 11% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Dexamethasone prices |
View all Hydrocortisone prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
De-Sone LA, Dexabliss, Dexamethasone Intensol, Dxevo, Hemady, HiDex, TaperDex, Zcort, ZoDex View more | Alkindi Sprinkle, Cortef, Cortenema, Cortifoam, Solu-Cortef | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
N/A |
12 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 793 drugs are known to interact with Dexamethasone:
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A total of 623 drugs are known to interact with Hydrocortisone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
October 30, 1958 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.