Comparing Guanfacine vs Modafinil
| Guanfacine | Modafinil |
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| Guanfacine | Modafinil |
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Prescription only
Guanfacine is used to treat high blood pressure alone or with other antihypertensives. Extended-release guanfacine is used to treat ADHD in children 6 years to 18 years. Dry mouth, sedation... View more |
Prescription only
Prescribed for Chronic Fatigue Syndrome, ADHD, Depression, Fatigue, Narcolepsy, Shift Work Sleep Disorder, Obstructive Sleep Apnea/Hypopnea Syndrome, Idiopathic Hypersomnia. Modafinil may also be... View more |
Related suggestions ADHD (Attention Deficit Hyperactivity Disorder)
Popular comparisons
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| More about Guanfacine | More about Modafinil | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Guanfacine has an average rating of 6.1 out of 10 from a total of 318 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 32% reported a negative effect. |
Modafinil has an average rating of 7.3 out of 10 from a total of 538 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Guanfacine side effects |
View all Modafinil side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Guanfacine prices |
View all Modafinil prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Intuniv | Provigil | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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18 hours |
15 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | |||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 492 drugs are known to interact with Guanfacine:
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A total of 524 drugs are known to interact with Modafinil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 27, 1986 |
December 24, 1998 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.