Guanfacine Pregnancy and Breastfeeding Warnings
Medically reviewed by Drugs.com. Last updated on May 16, 2022.
Guanfacine is also known as: Intuniv, Tenex
Guanfacine Pregnancy Warnings
Animal studies revealed reduced fetal survival at doses that produced maternal toxicity. There are no controlled data in human pregnancy.
US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
UK: Use is not recommended.
US: This drug should be used during pregnancy only if clearly needed.
US FDA pregnancy category: B
Comments: Adequate methods of contraception should be encouraged.
Guanfacine Breastfeeding Warnings
UK: A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
US: Other agents may be preferred; otherwise, caution is recommended.
Excreted into human milk: Unknown
Excreted into animal milk: Yes
Comments: The effects in the nursing infant are unknown.
See also
References for pregnancy information
- "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories (2001):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Intuniv (guanfacine)." Shire US Inc (2009):
References for breastfeeding information
- "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories (2001):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Intuniv (guanfacine)." Shire US Inc (2009):
- United States National Library of Medicine "Toxnet. Toxicology Data Network. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
