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Guanfacine Pregnancy and Breastfeeding Warnings

Brand names: Intuniv, Tenex

Medically reviewed by Drugs.com. Last updated on May 6, 2025.

Guanfacine Pregnancy Warnings

UK: Use is not recommended.
US: This drug should be used during pregnancy only if clearly needed.

US FDA pregnancy category: B

Comments: Adequate methods of contraception should be encouraged.

Animal studies revealed reduced fetal survival at doses that produced maternal toxicity. There are no controlled data in human pregnancy.

US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

See references

Guanfacine Breastfeeding Warnings

UK: A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
US: Other agents may be preferred; otherwise, caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Yes

Comments: The effects in the nursing infant are unknown.

See references

See also

References for pregnancy information

  1. (2001) "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics."
  3. (2009) "Product Information. Intuniv (guanfacine)." Shire US Inc

References for breastfeeding information

  1. (2001) "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics."
  3. (2009) "Product Information. Intuniv (guanfacine)." Shire US Inc
  4. United States National Library of Medicine (2013) Toxnet. Toxicology Data Network. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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