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Guanfacine Pregnancy and Breastfeeding Warnings

Guanfacine is also known as: Intuniv, Tenex

Medically reviewed on Mar 15, 2018

Guanfacine Pregnancy Warnings

Animal studies revealed reduced fetal survival at doses that produced maternal toxicity. There are no controlled data in human pregnancy.

US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

UK: Use is not recommended.
US: This drug should be used during pregnancy only if clearly needed.

US FDA pregnancy category: B

Comments: Adequate methods of contraception should be encouraged.

See references

Guanfacine Breastfeeding Warnings

UK: A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
US: Other agents may be preferred; otherwise, caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Yes

Comments: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  2. "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  3. "Product Information. Intuniv (guanfacine)." Shire US Inc, Florence, KY.

References for breastfeeding information

  1. United States National Library of Medicine "Toxnet. Toxicology Data Network. Available from: URL: http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT." ([cited 2013 -]):
  2. "Product Information. Intuniv (guanfacine)." Shire US Inc, Florence, KY.
  3. "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories, Philadelphia, PA.
  4. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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