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Guanfacine Pregnancy and Breastfeeding Warnings

Medically reviewed by Drugs.com. Last updated on May 16, 2022.

Guanfacine is also known as: Intuniv, Tenex

Guanfacine Pregnancy Warnings

Animal studies revealed reduced fetal survival at doses that produced maternal toxicity. There are no controlled data in human pregnancy.

US FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

UK: Use is not recommended.
US: This drug should be used during pregnancy only if clearly needed.

US FDA pregnancy category: B

Comments: Adequate methods of contraception should be encouraged.

See references

Guanfacine Breastfeeding Warnings

UK: A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.
US: Other agents may be preferred; otherwise, caution is recommended.

Excreted into human milk: Unknown
Excreted into animal milk: Yes

Comments: The effects in the nursing infant are unknown.

See references

References for pregnancy information

  1. "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories (2001):
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Intuniv (guanfacine)." Shire US Inc (2009):

References for breastfeeding information

  1. "Product Information. Tenex (guanfacine)." Wyeth-Ayerst Laboratories (2001):
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. Intuniv (guanfacine)." Shire US Inc (2009):
  4. United States National Library of Medicine "Toxnet. Toxicology Data Network. http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?LACT" (2013):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.