Comparing Estradiol vs Yuvafem

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Estradiol	Yuvafem (estradiol)	Enter another drug to compare

Estradiol

Yuvafem (estradiol)

Prescription only

Estradiol is a synthetic form of estrogen that may be given for several different indications, including the relief of menopausal symptoms or low estrogen levels caused by other conditions. Its use... View more

Prescription only

Prescribed for Atrophic Vaginitis, Atrophic Urethritis. Yuvafem may also be used for purposes not listed in this medication guide.

More about Estradiol

More about Yuvafem (estradiol)

Ratings & Reviews

Estradiol has an average rating of 5.8 out of 10 from a total of 589 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 37% reported a negative effect.

Yuvafem has an average rating of 3.2 out of 10 from a total of 107 ratings on Drugs.com. 18% of reviewers reported a positive effect, while 69% reported a negative effect.

View all 589 reviews

View all 107 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Hot flashes (17.5%)
Itching (7.1%)
Night sweats (6.1%)
Insomnia (5.3%)
Headaches (5.1%)
Mood swings (4.2%)
Rash (4.1%)

View all Estradiol side effects

Burning (17.8%)
Itching (11.2%)
Vaginal issues (8.4%)
Discharge (7.5%)
Urinary tract infection (7.5%)
Discomfort (5.6%)
Dryness (5.6%)

View all Yuvafem side effects

Drug Class

Estrogens

Generic Availability

Lower cost generic

Lower cost generic approved

Pricing and Coupons * Prices are without insurance

Quantity	30 tablet
Strength	1 mg
Per unit^*	$0.54
Cost^*	$16.14

View all Estradiol prices

Quantity	8 insert
Strength	10 mcg
Per unit^*	$8.16
Cost^*	$65.28

View all Yuvafem prices

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Dosage Forms

Intramuscular solution
Oral tablet
Transdermal gel

Vaginal insert
Vaginal tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

16 hours

N/A

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category X Not for use in pregnancy

See the full pregnancy warnings document.

Category X Not for use in pregnancy

See the full pregnancy warnings document.

Drug Interactions

A total of 375 drugs are known to interact with Estradiol:

32 major drug interactions (79 brand and generic names)
323 moderate drug interactions (1210 brand and generic names)
20 minor drug interactions (98 brand and generic names)

A total of 244 drugs are known to interact with Yuvafem:

32 major drug interactions (79 brand and generic names)
196 moderate drug interactions (739 brand and generic names)
16 minor drug interactions (60 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

July 23, 1975

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Estradiol uses

Yuvafem uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Estradiol vs Yuvafem

See also:

Botox

Fosamax

Gemtesa

Myrbetriq

Premarin

Reclast

Estrace

Provera

Zometa

Eligard

Further information

Comparing Estradiol vs Yuvafem

See also:

Further information

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