Effexor XR Alternatives Compared
Effexor XR | Bupropion | Cymbalta |
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Effexor XR (venlafaxine) | Bupropion | Cymbalta (duloxetine) |
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Prescription only
Prescribed for Autism, Major Depressive Disorder, Anxiety, Depression, Generalized Anxiety Disorder, Postpartum Depression, Panic Disorder, Social Anxiety Disorder, Vulvodynia. Effexor XR may also be... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Related suggestions Depression
Major Depressive Disorder
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More about Effexor XR (venlafaxine) | More about Bupropion | More about Cymbalta (duloxetine) | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Effexor XR has an average rating of 6.8 out of 10 from a total of 997 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 24% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2856 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
Cymbalta has an average rating of 6.3 out of 10 from a total of 1881 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Effexor XR side effects in more detail. |
See also: bupropion side effects in more detail. |
See also: Cymbalta side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Effexor XR prices |
View all bupropion prices |
View all Cymbalta prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Other venlafaxine brands include: Effexor | Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Other duloxetine brands include: Drizalma Sprinkle, Irenka | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
4 hours |
30 hours |
17 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 684 drugs are known to interact with Effexor XR:
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A total of 497 drugs are known to interact with bupropion:
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A total of 592 drugs are known to interact with Cymbalta:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
October 20, 1997 |
December 30, 1985 |
N/A |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.