Comparing Clindamycin vs Metronidazole

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Clindamycin

Metronidazole

Clindamycin is an antibiotic that is usually reserved for treating anaerobic infections or other serious infections caused by gram-positive bacteria in penicillin-allergic people. The risk of C... View more

Metronidazole is an antibiotic that is particularly effective at treating infections caused by susceptible anaerobic bacteria and parasites. Alcohol and products containing propylene glycol should... View more

Prescription only

Pricing and Coupons

* Prices are without insurance

Quantity	4 capsule
Dosage	150 mg
Per Unit^*	$2.88
Cost^*	$11.50

View all clindamycin prices

Quantity	1 tablet
Dosage	500 mg
Per Unit^*	$9.72
Cost^*	$9.72

View all metronidazole prices

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Generic Availability

Yes (this medicine)

Dosage Form(s) Available

Injectable solution
Intravenous solution
Oral capsule
Oral powder for reconstitution

Intravenous solution
Oral capsule
Oral tablet

Brand Names

Cleocin, Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage Flagyl, Flagyl 375, Flagyl IV, Metro, Metro IV

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

3.4 hours

20 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full Pregnancy Warnings document.

Category B No proven risk in humans

See the full Pregnancy Warnings document.

Drug Interactions

A total of 75 drugs are known to interact with clindamycin:

3 major drug interactions (8 brand and generic names)
70 moderate drug interactions (307 brand and generic names)
2 minor drug interactions (7 brand and generic names)

A total of 327 drugs are known to interact with metronidazole:

10 major drug interactions (29 brand and generic names)
132 moderate drug interactions (473 brand and generic names)
185 minor drug interactions (587 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Consumption of alcoholic beverages or products containing alcohol or propylene glycol during... View more

Disease Interactions

First Approval Date

February 22, 1970

July 18, 1963

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer