Comparing Amphetamine / Dextroamphetamine vs Methylphenidate
| Amphetamine / dextroamphetamine Remove Amphetamine / dextroamphetamine from your drug comparison | Methylphenidate Remove Methylphenidate from your drug comparison |
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| Amphetamine / dextroamphetamine Remove Amphetamine / dextroamphetamine from your drug comparison | Methylphenidate Remove Methylphenidate from your drug comparison | ||||||||||||||||
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Amphetamine-dextroamphetamine is a stimulant-type medicine used to treat ADHD and narcolepsy. Its use is limited by its addiction potential and risk of abuse. Prescribed for ADHD, Narcolepsy. May... View more |
Methylphenidate improves symptoms of ADHD but carries with it a risk of dependence and side effects such as insomnia are common. To avoid insomnia the last dose should be administered before 6pm... View more |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: headache, insomnia, weight loss, anorexia, and xerostomia. See the full amphetamine / dextroamphetamine side effects document. |
Commonly reported side effects include: insomnia, nausea, headache, vomiting, decreased appetite, and xerostomia. See the full methylphenidate side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all methylphenidate prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Adderall, Adderall XR, Mydayis | Adhansia XR, Aptensio XR, Concerta, Cotempla XR-ODT, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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34 hours |
4 hours |
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CSA Schedule**View glossary of terms. |
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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Pregnancy Category |
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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Drug Interactions |
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A total of 180 drugs are known to interact with amphetamine / dextroamphetamine:
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A total of 184 drugs are known to interact with methylphenidate:
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Alcohol/Food/Lifestyle Interactions |
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Disease Interactions |
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First Approval Date |
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September 09, 1955 |
December 05, 1955 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.