Comparing Amphetamine / Dextroamphetamine vs Methylphenidate
| Amphetamine / dextroamphetamine | Methylphenidate |
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| Amphetamine / dextroamphetamine | Methylphenidate |
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Prescription only
Amphetamine-dextroamphetamine is a stimulant-type medicine used to treat ADHD and narcolepsy. Its use is limited by its addiction potential and risk of abuse. Prescribed for ADHD, Narcolepsy. May... View more |
Prescription only
Methylphenidate improves symptoms of ADHD but carries with it a risk of dependence and side effects such as insomnia are common. To avoid insomnia the last dose should be administered before 6pm... View more |
Related suggestions ADHD (Attention Deficit Hyperactivity Disorder)
Fatigue
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| More about Amphetamine / dextroamphetamine | More about Methylphenidate | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Amphetamine / dextroamphetamine has an average rating of 7.0 out of 10 from a total of 1068 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 22% reported a negative effect. |
Methylphenidate has an average rating of 7.1 out of 10 from a total of 999 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 17% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Commonly reported side effects include:
See also: amphetamine / dextroamphetamine side effects in more detail. |
Commonly reported side effects include:
See also: methylphenidate side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
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View all methylphenidate prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Adderall, Adderall XR, Mydayis | Adhansia XR, Aptensio XR, Concerta, Cotempla XR-ODT, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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34 hours |
4 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 180 drugs are known to interact with amphetamine / dextroamphetamine:
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A total of 184 drugs are known to interact with methylphenidate:
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 09, 1955 |
December 05, 1955 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.