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User Reviews for Trazodone to treat Depression

Also known as: Desyrel, Desyrel Dividose

Trazodone has an average rating of 6.7 out of 10 from a total of 120 ratings for the treatment of Depression. 58% of reviewers reported a positive experience, while 29% reported a negative experience.

Trazodone rating summary

6.7/10 average rating

120 ratings from 129 user reviews.

Compare all 188 medications used in the treatment of Depression.

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29%
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8%
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Reviews for Trazodone

Gomattgo · Taken for less than 1 month · March 17, 2014

“Before taking Trazodone I could not fall asleep at night, I began resorting to drinking just to fall asleep at night and that alone has it's fair share of negative consequences. Literally the first night I took a 50mg Trazodone I was able to fall asleep and stay asleep. I've been on the medication for nearly a month now and I can happily say that I can't remember the last time I've felt this great! I don't feel the need to drink whatsoever. I fall asleep within 30 minutes of taking the tablet, I stay asleep, and I wake up well rested with a much more positive outlook on life! I can't wait to see what the future holds. I strongly recommend this medication for anyone suffering from depression, anxiety, and/or sleep deprivation.”

9 / 10
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CKib · Taken for 1 to 6 months · September 20, 2014

“This has helped me endlessly. I started taking it about 5 months ago, The first thing that it helps with is sleep, I'll fall asleep so easily & not wake, One thing I noticed however was the vivid dreaming, not too bad if you aren't freaked out by bad or plain weird dreams. For the first few days/weeks it was harder to get up in the morning but having caffeine really helps. I would always feel low before this medication, sad, hopeless and have no energy. With it I'm more confident, make more effort with other people, not afraid of my own company and anything that happens I can see logically. One of my problems was illogical thinking and this has reduced that by 90%. You'll have to be more careful with alcohol on this medication.”

10 / 10
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kjhand · June 20, 2014

“Originally I started taking trazodone for insomnia, but was fearful of taking too much so I minimized my dose and that was a mistake. I believe its important to take the amount that starts working consistently for you as you titrate up to a dose that starts working. And you need to give it time to build up in your system. I'm up to 250 mg when I go to bed, I will take another 50 mg and that tends to give me a couple hours more sleep if I wake up too early. What's really amazing about this medicine is that I no longer struggle with depression or anxiety. It keeps my brain in chemical balance and I think clearly with no side effects, except I'm a little tired in the morning. So I drink a big cup of coffee and that helps.”

10 / 10
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Zilo · Taken for 1 to 6 months · June 5, 2017

“With all due respect, don't listen to the naysayers. Its a great medication. No loading period, you can come off at anytime and it is only mildly addicting when taken in high doses for long periods. You will sleep, it will keep your anxiety and depression in check and it will allow you to be yourself again. People who tried it for a night and complain in reviews have not given it a chance. I don't understand, do they prefer to have their brain chemistry altered forever by paxil? lol Trazadone is a SARI and a minor one at that. I don't want to be a slave to paxil and the like forever, hence traz is a much better option.”

10 / 10
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BC chic.. · December 5, 2013

“I was a basket case, I cried every day for no reason. A commercial would set me off, my emotions we're out of control and I knew it but I couldn't stop it. I couldn't sleep either. My doctor then put me on trazodone, within three days I was starting to feel like my old safe again. I was on it for years. I tried to get off but the same thing happened again, so I went back on trazodone. For me, it works. I hate taking pills but sometimes you have to.”

8 / 10
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21855000906992 · Taken for less than 1 month · August 23, 2019

“I have insomnia and depression. I’ve tried a lot of antidepressants and I found I’m also having trouble sleeping and struggling with depression. I’m 63 years old. My doctor prescribed trazodone 50 mg and I’ve only had it one night so far. I haven’t had a good night sleep in a long time and I actually feel human today. I’m very sensitive to meds so I had to cut the 50 mg and I’m going to try 25 mg tonight because I felt a bit groggy this morning but I am sensitive to meds. I really am hopeful for this to work. A bit soon to have an opinion but I haven’t felt this good in a long time. Also told it’s not habit forming. I was sleepy 15 minutes after I took it. And oh yes make sure there’s food in your stomach. Made me feel a bit nauseous so I had a couple soda crackers. Hope this helps some people I’ve seen a lot of positive comments made. Have a great day. ❤️ ”

10 / 10
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jess · Taken for 6 months to 1 year · August 3, 2020

“been on trazadone for a while it made me feel terrible couldn't control my mind I thought it was me and all along it was trazadone terrible drug please think before you take this it has ruined my life felt scared all the time really shaky and anxious I'VE STOPPED IT NOW”

1 / 10
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Frequently asked questions

noodles · Taken for 1 to 6 months · April 25, 2019

“Trazodone helped me so much, I felt a boost in my confidence, I slept better at nights and my energy levels were so high. I felt so great everyday when I took them, I would always take them 9pm at night, then get tired half an hour after taking them. It definitely helped with sleep. I was ready for the day at 7am. I had so much motivation while on this medication. For anyone that is thinking of starting Trazodone, remember it takes a month to get the full effect. It doesn't start working as soon as you start taking it. I think it does work with sleep right away because it makes you drowsy after taking it.”

10 / 10
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micaela3723 · September 4, 2015

“My Dr. prescribed trazadone for ptsd and depression. I haven't had a good nights sleep due to my mind racing and thinking of my past. I have noticed I've been able to sleep and wake up in a good mood and feel well rested , I've even enrolled in college and doing great in my classes.Looking forward to the future :) I don't have insurance but my provider is paying for my medication.”

7 / 10
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Georgina · Taken for 1 to 6 months · December 19, 2019

“Trazodone is absolutely great for me. I'm taking 100 mg of it every night due to terrible insomnia and persisting depression. Sertraline was only making me more miserable, but trazodone worked from day 1. I sleep a lot better and have much less trouble with bad thoughts and bad mood. Some people say it makes them feel groggy, but it's just perfect for me. This medicine is not used very often as an antidepressant, but it does worth trying it if other medicines don't fit you.”

10 / 10
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Uncle Scooby · Taken for 6 months to 1 year · April 15, 2015

“I take 50mg Trazodone before bed. It helps me get a full night's sleep and eases my depression during the day. I don't think I'd benefit from taking it first thing in the morning because it's a very sedating drug. I also find Trazodone to be an affective long-term pain killer. Trazodone doesn't belong to any of the common classes of anti-depressant so it doesn't kill my libido like SSRIs and SNRIs tend to do.”

9 / 10
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freednerd · Taken for 5 to 10 years · February 27, 2013

“One of my favorite medicines of all time. I have taken this for depression/bipolar disorder, insomnia, and currently fibromyalgia. It is the only anti-depressant I have found that I can take and not start swinging toward the manic side. I actually feel more refreshed and get a good night's sleep after I take it. I will note that I do not normally take it for long periods of time- only when I need it (this may be days, weeks, or months). There is no withdrawal and you do not have to dose up or down with safety concerns.”

10 / 10
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stars little sleeper · November 17, 2010

“I have suffered with severe depression, uncontrollable anger and violent outbursts, paranoia, anxiety and sleep problems. I have tried several different anti-depressants and found they all made me worse or didn't help at all. I've been taking trazodone 8 months now and my life has totally turned round. I'm on the ball at work, approachable, negativity has gone, it feels like a giant weight has been lifted off my shoulders, clear thought processes, friendlier and my relationship has turned around. I have a future. Amazing all this started with 150mg and now on 250mg of the little magic capsules. Thank God for this medicine, I can sleep easy. I'm normal.”

10 / 10
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Cat · April 30, 2020

“Doc prescribed me Trazodone for Depression. I started with 25mg because I react very sensitive to meds and the first night I had arrythmia, anxiety, cold sweat and insomnia. These side effects disappeared after 2 weeks except for occasional arrythmia. I slept well in the beginning, but I was also extremely tired during the day. I felt a bit more emotionally stable so I started taking 50mg which was a horrible decision. I had severe sexual dysfunction, wasn't able to feel anything during sex, I slept all day, felt extremely weak, my heart was pounding and I felt like I had to faint a lot. It did nothing for my depression, I felt worse than before! I was crying a lot, and when I wasn't crying I didn't feel anything at all. After a few weeks on 50mg I stopped taking it because I couldn't handle the side effects. Overall I was on Trazodone for 2,5 months. I had withdrawal symptoms like Insomnia, extreme anxiety, suicidal thoughts and others. I can't recommend this medication to anyone.”

2 / 10
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Mart72 · July 25, 2013

“Take 100mg a hour before bed with good sleep results. Mornings can be foggy but nothing a few coffees won't fix. As for daytime results can feel the depression lifting with reduced anxiety (no mania,) this medication a life saver great stuff.”

10 / 10
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Sandy Madagasgar · January 5, 2014

“I started this medication when I was experiencing flashbacks to trauma and I would wake up in a sweat, screaming or sleepwalking. I take many other medications to help with Post Traumatic Stress Disorder, depression and bipolar. It worked wonderfully well for 7 years. I stopped taking this when I got a new doctor as she wanted to lower my dose of medications. I have now been consistently having nightmares and am hitting, kicking and punching my husband at night. He wakes me to this. I feel terrible about this because my husband has been a wonderful support for the last 20 years. I want to go back on trazodone. Its the only thing that will work for me.”

9 / 10
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T Alger · December 4, 2013

“After many, many years of taking Zoloft for depression, It got to a point where it was not as helpful as it once was. I visited my doctor who put me on trazodone as a booster to the Zoloft that I was still taking. In 2 weeks I noticed the difference. I no longer feel depressed and feel more like my old self again. The only side effect I have had is a little blurred vision...I'll take that any day over depression.”

10 / 10
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More FAQ

Island Girl · Taken for less than 1 month · June 4, 2020

“My doctor prescribed this since Prozac and brintellix wiped me out sexually. Apart from the issue with libido, Prozac suited me perfectly, not so however this drug Trazodone. I was told to take 150mg..which in the light of these reviews seems extreme considering my sensitivity to drugs and my body weight, being petite. As instructed I took it five hours before bedtime. I then slept like a zombie for ten hours and woke feeling groggy with super spaced out eyes the next morning. I felt heavy, drugged and seemed to have lost my sense of balance. It took till lunchtime to feel vaguely normal again. While I do not doubt this would prevent the panic attacks as you would be too out of it to panic, whatever the issue, nuclear attack, invasion of the body snatchers, aliens abducting your children. I had no intention of suffering such extreme side effects. Consequently, I did not take again. The search goes on for the perfect drug. It most definitely is not this one.”

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BME · Taken for 5 to 10 years · April 11, 2014

“I was in a deep dark hole into which no light or joy came no matter what nice and kind things my family did to help. I had uuncontrollable crying bouts that might occur at any time. A friend told me Desyrel had helped her so I asked my doctor for a scrip. From the first dose I knew I was on to something. Slept well, woke rested did not interfer with intimacy with husband. Was mentally alert but took couple cups of coffee to get going. Did have moderate headache that went away in couple hours. Suddenly I was interested in life again, was able to resume handling our finances, organizing house, outings with friends. Was great. But after some time came.....weight gain, edema, and stomach on fire...slept in recliner lots. Not for long use.”

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Anonymous · June 14, 2011

“I recently lost my husband and I was prescribed Trazodone for depression. Before this, I was taking Ambien for sleeplessness. I am now off Ambien which gave me bad headaches, not only am I sleeping better than ever, but my depression seems to be somewhat in check. I do not expect any miracle medicine to take away the pain and sadness of losing the love of my life, but this is more than helping with no side effects at all.”

10 / 10
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Shaggin · Taken for 10 years or more · May 15, 2020

“I've been taking trazadone for many years for depression, anxiety and it also helps to minimize or eliminate thought disturbances and of course it helps you sleep. So this medication does a lot and overall I will say that it has been working for me. However I do not like taking this med as it sedates you so much its hard to wake up out of it. This is the one medication I wish I could wean myself off of. Sometimes I skip a dose or two but cannot get too far from it as I will start having symptoms of depression and anxiety again. So I'm pretty much dependent on it.”

7 / 10
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Mike · Taken for 1 to 6 months · April 17, 2018

“Trazodone is a life saver. I was horribly depressed and had crushing insomnia (I would go to sleep at 10pm and then be wide awake at 2am with my mind racing with dark thoughts) which never went away. I asked (begged) my PCP for a sleep aid and he prescribed Trazodone 50 mg. My entire outlook on life has changed - I can smile, look forward to and enjoy things in life again.”

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Deb96 · Taken for 1 to 6 months · December 15, 2015

“I was put onto Trazadone (started on 50mg then 100mg after 2 weeks) after having 3 months of citralopram which was not working for me. The trazadone has 100% helped my sleeping as I was only sleeping 1-2 hours per night. As for my depression it seems to helped so far, I'm still having episodes lasting 2 days to a week however these are a lot less frequent. Trazadone has helped my anxiety however I do still suffer from bouts of anxiety at least once a week (again better than before the trazadone). Personally I think that trazadone is great for treating sleeping problems, anxiety and depression and hopefully I will see even better results the longer I take it for.”

9 / 10
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trazo20years · Taken for 10 years or more · February 15, 2021

“I got prescribed trazodone 23 years ago for a sleeping aid. My doc thought I was depressed so gave me 300mg. I am still on 100mg every night and I am severely depressed I am in bed for around 16 hours a day. I have lost all interest in everything in life no motivation for anything. I am drained within 2 hours of getting up and have to go to bed again. I have tried a few times to get off trazodone but I get to around 55-60 hours awake and give up and take the trazodone again. My wife left me 10 years ago as she had enough of the way I was. Concentration and listening to people is difficult as you're not interested in what anyone's saying. I have been awake 33 hours so far (trying to get off trazodone again)and a bit teary thinking of the 20+ years I have slept in my bed for--its a bad drug for a lot of people”

1 / 10
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Lorincz · November 9, 2013

“This has been a miracle for me going through horrid menopause with terrible anxiety, worry and deep depression. I have been to point of wanting to end my life. I have tried over dozens of anti-depressants along with anti-anxiety meds but they made me feel worse. Now I am taking trazodone along with a couple of glasses of red wine along with Jasmine. The hot flashes are pretty much have gone away and get to sleep too. The anxiety and depression is now manageable thank God!! I would encourage all women do not allow your doctor to prescribe any benzos. It caused most of depression. The side effects were just horrible!!! It took me many months to overcome them. I had flu like symptoms and deep deep depression get ting of of them.”

9 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.