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VESIcare and Constipation: What Users Say

Constipation: mentioned by 22 users (15.5%)

Based on user experiences from 142 VESIcare reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

dry mouth 28.2%
constipation 15.5%
blurred vision 13.4%
headaches 8.5%
sore throat 6.3%
tiredness 5.6%
dry eyes 4.9%
dizziness 4.2%
fatigue 4.2%
drowsiness 3.5%

Reviews for VESIcare

Commonly mentioned side effects
  • von...
  • Taken for less than 1 month
  • October 21, 2013

For Urinary Frequency "I am a male with overactive bladder. Initially treated for prostate problem, as usual for men, but I have no prostate difficulty. Asked Dr. for Vesicare, after reviewing symptoms on internet sources. Vesicare is targeted at women by the drug co. Astellas, but I had the same symptoms. Started with the 5mg dose, and my symptoms significantly improved within the first few days. Severe bathroom urges every hour or two. Woke up to pee several times at night, sometimes every 2 hours; miss a bathroom, and pee in pants. A week later after starting Vesicare, get up once a night, or not at all, and bathroom visits are once in 3-5 hours. Wow, got my life back. Only nasty side effect is constipation, cured by taking pill less frequently than daily."

8 / 10
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217 Report
  • Kat...
  • February 24, 2013

For Urinary Incontinence "Prescribed for urinary incontinence, notably stress incontinence. I started with 5mg (eventually began 10 mg) of VESIcare, and it worked overnight. When I am running low on tablets and payday is off in the future, I have good success with taking 10mg every other night. Side effects: 1. Very dry mouth, but a good excuse to drink more water, keep TicTacs handy, over time, it has greatly diminished. 2. Drowsiness: I started taking it at night. 3. Constipation: drank more water and took a daily stool softener until my body readjusted."

10 / 10
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222 Report
  • Ste...
  • Taken for 1 to 6 months
  • January 20, 2019

For Urinary Frequency "I took VESIcare for 4 months. VESIcare did improve my overactive bladder, and the urinary urge did decrease. I did not immediately experience side effects except some constipation and reduced stool frequency. I also started getting full nights of sleep without waking to use the loo. That’s the positive part. After 2 months, I started getting occasional liquid diarrhea and then bouts of constipation lasting 3-4 days, then again liquid diarrhea. Throughout this time, lots of gas and cramping. The symptoms were on-off. Then after 3 months, I experienced continuous liquid diarrhea and gas/cramping after every meal. During the space of 30 days, I lost over 5kg in weight and had fatigue, very cold feet, and hands. I stopped VESIcare immediately, and normal bowel movements restored within 5 days. The fatigue and cold extremities have also gone. My conclusions: the VESIcare drug works, but the side effects are intolerable for a significant portion of patients, including myself."

3 / 10
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116 Report
  • Anonymous
  • Taken for 1 to 6 months
  • October 24, 2012

For Urinary Frequency "I am a 27-year-old female. I started noticing that I was going to the bathroom an average of 12 times a day. I was losing sleep because I would get up 2 or 3 times a night. At work, I was constantly running to the bathroom, which seemed like every hour. I went to my OB/GYN, who gave me a test and started me on 10mg of VESIcare. Within the first day, I saw instant results. I have been taking it for over a month, and about 2 weeks ago, I started to have severe abdominal pains, constipation, lower back pains, as well as light-colored stool. I lowered my dosage to 5mg, and everything seemed to improve until today. I experienced the same severe side effects again, so I had to stop taking it."

3 / 10
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144 Report
  • fre...
  • March 24, 2014

For Urinary Incontinence "I started using VESIcare about 7 months ago and it worked fantastic. Side effects are going to make me stop it today: dry mouth, raspy voice, blurred vision, sore throat, constipation, and leg cramps (we used to call them charlie horses). I am 81 years old and can't stand the pain in my leg all day and night, it's worse. But for the incontinence, it was a blessing not to have to run to the bathroom every few hours and not make it home from shopping without being wet. I have tried Detrol but get terrific headaches from that. I will see my doctor and hopefully we can work something out. I am on the 5 mg."

10 / 10
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115 Report

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  • 123...
  • Taken for 6 months to 1 year
  • March 11, 2014

For Urinary Frequency "I am only 26 and was going to the bathroom every hour, and sometimes every half an hour during the day. I took VESIcare for 7 months and saw a decent decrease in the number of trips to the bathroom. However, I was often constipated, bloated, had a headache, and experienced a change in eye prescription. I stopped taking the medication and switched to another. It took 6 months before my eye prescription stabilized to where it had originally been before VESIcare."

3 / 10
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122 Report
  • Anonymous
  • Taken for 2 to 5 years
  • October 31, 2014

For Urinary Incontinence "I took VESIcare for interstitial cystitis, and it was life-changing! I'd go to the bathroom about every 7 to 10 minutes for a period of about 5 hours during the day and 3 to 4 times at night and pretty much incontinent. I was miserable. The only side effects I had were dry mouth and constipation. But me only going to the bathroom every few hours, less pain, and not waking up at night was worth it to me. I lost my insurance that paid for it and had to be off of it for a year and just now got assistance for it through my doctor's office pharmacy, and I couldn't be happier to get back on it and start feeling better!"

9 / 10
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103 Report
  • nur...
  • Taken for 1 to 6 months
  • January 19, 2017

For Urinary Frequency "My bladder was out of control! Having to urinate almost every 45 minutes to an hour. Seriously, I was going 25-30 times a day. It was awful. The doctor put me on VESIcare 5 mg. It worked great from the 2-3 days, however, after a week or so, my symptoms came back. He decided to put me on the 10 mg. At first, my mouth and eyes were very dry, I almost stopped taking it. I decided to give it some time and see what happened. The drug was a lifesaver for me, the dry mouth and eyes went away after the 2nd week. Constipation was kind of an issue, but I started using Miralax and had no problems at all. Well, that is until about 3-4 weeks of taking the 10 mg... It seems as though my symptoms are coming back."

5 / 10
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42 Report
  • Cri...
  • November 15, 2019

For Urinary Frequency "My side effects from VESIcare are constipation, dry mouth, dizziness, sore throat, itching, and burning. I have some reduction in urinary frequency but not enough to justify the side effects. Took for 35 days."

4 / 10
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28 Report
  • flo...
  • Taken for 1 to 6 months
  • June 11, 2016

For Urinary Frequency "I'm 21 and recently started taking VESIcare, at first, it was 10 mg, but I literally could not poop. I would go 2-3 days without pooping and had severe heartburn. My doctor lowered it to 5 mg, and it helps a bit with the urinating, but I do notice in situations where I'm stressed it doesn't seem to work as well, but when I'm relaxed, it's perfectly fine. Also, with the 5 mg, I'm still having constipation and only poop about every other day, and I'm still having bad heartburn every few weeks or so. I'm not sure if I want to stick with this medication or not because I should not be having this bad of heartburn at 21."

9 / 10
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40 Report
  • Sil...
  • April 30, 2015

For Urinary Frequency "Have been on VESIcare for 3 or 4 years now and am on 10 mg a day. I remember the doctor saying that dry mouth can be a side effect, but now after reading all these comments about constipation and pain, etc., I'm a little concerned that she never warned me about these. Although I have never experienced these, if I had, I would have not connected it to being a side effect from the medication. I notice that if I stop taking it for a week or so, things get bad, and I have no control whatsoever. I feel like I will be on this medication for a very, very long time, but I guess it's worth it. Even though I am taking 10 mg a day, I still go to the toilet a lot, but I have some control back, which is great. People still comment on the amount of times I go to the toilet."

7 / 10
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44 Report
  • 46f...
  • Taken for 1 to 6 months
  • February 12, 2019

For Urinary Incontinence "I was put on VESIcare after experiencing urinary incontinence while running. To the point that I could not hold it in before I got home. I also lost my urine during sex and was starting to have to rush to the bathroom within 2 minutes of feeling the need to go. VESIcare worked great! I go half as often, can wait up to 45 minutes before finding a toilet, and can run “home free”! However, the side effects are horrible. Feeling bloated, constipated, and feeling like I drank an ocean of salt water - all the time, day and night. Nothing could relieve this. I tried everything from laxatives to curcuma to fiber and water to changing my diet. The pharmacist said that was to be expected. But it was too much for me, so I quit the meds. Two days later, side effects are still in full swing, but all my symptoms are back! Quite discouraging. I am a fit person, 46, no kids, and sexually active. If this medication had less severe side effects, I would give it a 10."

8 / 10
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29 Report
  • Wea...
  • August 31, 2016

For Urinary Incontinence "Started 3 nights ago, 5 mg. I take it in the evening after dinner. On the first morning, I was constipated, but no side effects since. I notice a huge difference. My pads are staying dry. I smoke, and when I cough, it's the only time I leak now. My insurance covers it, and my co-pay is only $3.65. I can't wait to see if this works long-term. I'm lucky to have no side effects, as I seem to be allergic to everything. My metabolism seems to be slower than most people, so I think the 5 mg is enough for me. I worry about weight gain because I'm already considered obese. Before I started taking it, I would leak for no reason at all. I would have to use 4 or 5 pads a day. Nights were horrible, I would wake up soaked. Not anymore."

9 / 10
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37 Report
  • Anonymous
  • March 5, 2011

For Urinary Frequency "I got positive results after the first tablet. I stayed with the medication for two weeks but had to discontinue use due to constipation. In fact, the constipation was so bad in the second week I was giving myself enemas to get relief."

4 / 10
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48 Report
  • LaT...
  • Taken for less than 1 month
  • October 14, 2015

For Urinary Frequency "Been having cold-like symptoms. Running nose, sneezing, stomach pain, constipation, heart beating too fast. I've been taking only 4 days but stopped today. Side effects are too much, and they're making me miserable."

2 / 10
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31 Report
  • Anonymous
  • December 2, 2011

For Urinary Frequency "The relief from 'leakage' was moderate to good, but I continued to have to use feminine hygiene pads. I was 'down' to six changes a day, which was a real improvement. However, I had no idea what real constipation was about and how severe it could be until VESIcare. All in all, the cost/benefit ratio just wasn't there. Speaking of cost, the price was outrageous."

4 / 10
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41 Report
  • Giz...
  • September 7, 2016

For Urinary Frequency "It was helping with the frequency. I still have bad days. Started it on March 16. I also have a problem with constipation. I don't eat or drink enough, have lost 2 and a half stone. As I live in the UK, I don't have to pay full price, just a prescription charge. I find I have become obsessed and anxious about it not continuing to give me some relief. I will be going back to the doctors for more help with this distressing condition."

5 / 10
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24 Report
  • Hea...
  • July 10, 2017

For Urinary Frequency "Besides the high cost, the effectiveness of this medication is diminished due to the side effects. I started on this medication for nine days and stopped. Constipation was the primary side effect almost on the first day, the worst I ever had, in addition to abdominal pain, slight headache, and bloating. My doctor did warn me about the side effects."

2 / 10
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23 Report
  • Zoe...
  • Taken for 1 to 6 months
  • August 10, 2016

For Urinary Frequency "Found myself getting up 4-8 times a day and needing the toilet a lot during the day. First prescribed 5 mg, and it did absolutely nothing, so the doctor upped them to 10 mg and still nothing except constipation. So I've stopped them and will just have to deal with it."

2 / 10
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22 Report
  • Aaa...
  • Taken for 1 to 6 months
  • March 14, 2025

For Urinary Incontinence "I've had stress urinary incontinence for over 2 years and never considered taking meds, pissed myself like every week and never slept good because it made me wake up like 2 or 3 times a night, plus having pain in my bladder. Started taking VESIcare 5 ml 5 months ago. Honestly, it's really good. I started seeing changes since the first month. I piss myself rarely now and don't wake up at night, maybe just once a night. I'll continue using it for 5 more months, maybe more. The only bad thing is the side effects, which are so annoying to me: really bad constipation, blurred vision, stomach pain, bad headaches, bad drowsiness, and fatigue, which affects my life because it makes me unable to do anything in my day, plus dryness. Me and my doctor still can't figure out the reason because it started when I was only 15. But anyways, it's a good med, just bad side effects."

7 / 10
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0 Report
  • Anonymous
  • December 10, 2008

For Urinary Frequency "This worked great but caused bad constipation. I know it was from VESIcare because I have never had constipation before."

8 / 10
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73 Report
  • Pud...
  • Taken for 1 to 6 months
  • February 17, 2021

For Urinary Frequency "VESIcare was effective at controlling bladder spasms. I experienced very dry mouth, constipation, blurred vision."

7 / 10
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10 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.