Simvastatin User Reviews & Ratings (Page 3)
Brand names: Zocor, FloLipid
Simvastatin has an average rating of 4.8 out of 10 from a total of 131 reviews on Drugs.com. 30% of reviewers reported a positive experience, while 48% reported a negative experience.
Reviews for Simvastatin
- doo...
- November 9, 2017
For High Cholesterol "Interesting reviews. Over the years, I've been on one cholesterol drug or another. My numbers are down and acceptable to my GP. The latest is the generic simvastatin. Muscle soreness in legs, hips, and wrists have seemed to be my life. Up every two hours to pee like clockwork, sometimes more irritable for no apparent reason, and irregular heartbeats I can feel, and are picked up by my BP machine. After reading these reviews, I'm going to self-de-medicate for a spell to see if my sleep pattern changes, as well as other possible side effects I've listed. It seems too many people have the same symptoms as me, and have stopped taking the medication with positive results."
- mar...
- August 18, 2011
For High Cholesterol "Had taken medication for 8 months, noticed that my muscle control was weakening and had acid reflux, which I had to take medication for. After going off this medication, my muscle control strengthened and acid reflux was gone."
Frequently asked questions
- Do statins cause rhabdomyolysis, and how is it treated?
- When is the best time to take simvastatin?
- Can I drink grapefruit juice with simvastatin?
- What are the side effects of statins?
- exm...
- November 23, 2017
For High Cholesterol "I have been taking Zocor for years, and in that time, I have developed a side effect which, in talking to others on the same drug, is quite common... cold hands and feet. I started on 10 mg and presently take 40 mg. My cholesterol has been reduced, but the discomfort associated with coldness at all times, regardless of temperature and amount of clothing worn, is very disconcerting. I have discussed this with several doctors, and they all say it's a side effect of Zocor. I cannot find this in the list of published side effects. I have also tried Lipitor, but the results were actually worse. What to do?"
- 480...
- Taken for less than 1 month
- August 14, 2017
For High Cholesterol "20 mg x 2 days... 1. Severe headache 2. No energy 3. Weakness 4. Very sleepy 5. Pain in ribs (L side more). I have discontinued the statin and will change diet, take fish oil, and low dose aspirin daily."
Are you taking this medicine?
Your review helps others make informed decisions.- big...
- Taken for 1 to 6 months
- March 19, 2014
For Hyperlipoproteinemia "Simvastatin 40 mg, one tablet taken at bedtime. I weighed about 240 lbs. This medicine is effective at lowering lipids and triglycerides when taken regularly. Clinical trials prove these medicines lower stroke and heart attack risk. Also take soluble fiber immediately after meals when possible to supplement cholesterol reduction and vitamin B6 to lower homocysteine levels. Skip a dose if you are going to have alcoholic beverages that evening or day, so it doesn't overtax your liver. Same with acetaminophen. Most noticeable side effect is mild insomnia and some mild muscle stiffness, both managed with daily yoga and regular exercise. Hoping to get lowering dose to 20 mg in a month or so, assuming blood tests show positive results."
- Bar...
- Taken for 10 years or more
- March 13, 2019
For High Cholesterol "Have used simvastatin 40 mg for years. Had been taking Teva generic without a problem. I was given Dr. Reddy generic simvastatin on one occasion (due to lower price), and I developed flu-like symptoms (fatigue, body aches, and general run-down feeling) almost immediately. Since then, my doc has specified Teva brand, even though it costs more, since I've never had any issues with that. The generics are supposed to be the 'same.' However, the inactive ingredients and method of dispersal in the bloodstream can have differing effects on different people. Rhabdomyolysis runs in my family, and I don't want to take any chances with other generic brands."
More FAQ
- How do you manage muscle pain with cholesterol drugs?
- Do statins help treat COVID-19?
- What should you know about "Statin" Medications?
- Tag...
- Taken for less than 1 month
- September 21, 2012
For High Cholesterol "I am on 20 mg. I take it right before I go to bed. After 15 minutes, my heart starts racing. However, I have no problems falling asleep. If I had to take this in the morning, I wouldn't be able to stand the racing heart. Other than that, I feel good so far. My cholesterol was 204 and triglycerides are at 130. I am 43 and have started walking 3 miles at a good pace 5-6 days a week. Drinking lots of water and no caffeine. I have just had my next blood work since being on this medicine, so we'll see if it's doing its job."
- Bab...
- Taken for 6 months to 1 year
- February 4, 2021
For High Cholesterol "While taking statins, I tried many different brands. I experienced some of the worst side effects. I am a 72-year-old retired registered nurse. I first started waking up in the middle of the night with horrible cramps in my legs, it felt as if a knife was sticking in my leg. Then I developed a rash under my breasts, which, after being prescribed four different creams, just got worse. Then I got gout in my big toe, and when I woke up in the morning, my feet felt numb. The gout was so painful. I realize that I need statins because of my LDL and carotid artery blockage, but when I stopped using the statin, all these different symptoms went away."
- hap...
- June 18, 2015
For High Cholesterol "Have taken Simvastatin 80 mg for eight years. Cholesterol level is down and stable. I wake up some nights around 3 p.m., wide awake. I get irritable and angry at times, high tummy pains, some days the need to urinate quite often. I didn't realize until reading information here that it may be the statins causing these side effects. All in all, I'm happy with the results."
- hon...
- Taken for 10 years or more
- December 5, 2018
For High Cholesterol "Took this drug for ten years. The past year, I have been having trouble breathing and doing any physical exercise at all. The pharmacy ran out of the drug, and after three days, all the trouble I was having went away. The GP is going to change to another drug. Before taking any prescription, do some research online, and if you don't like what you read, go to your GP and discuss."
- Bar...
- October 8, 2011
For Cardiovascular Risk Reduction "58 yr old male. Heart attack 7 months ago, 98% blocked right coronary artery, stented. Been on Simvastatin and Plavix since I got my stent. Was on Lisinopril, but it caused hives. Not sure what is causing it, but I have been freezing cold all summer, shivering cold. My legs ache almost constantly. Got blood work done this week, I will be seeing the doctor in a few days and get the results. If I find that it was this medicine causing the chills, I will discontinue it."
- Anonymous
- December 30, 2010
For High Cholesterol "Took simvastatin only once and had a bad case of vertigo within 30 minutes of going to sleep. The next day I felt okay for the most part, but that night I was playing drums in my band and had to stop after 40 minutes (we normally practice an hour and a half or more) because I was so exhausted. The rest of the night I felt like my whole body was being squeezed, and my muscles were really weak. I woke up three times during the night with my heart racing and feeling like I was going to pass out. I drank one liter of water in two hours, and finally fell asleep at 4 AM. If I hadn't improved after 4 AM, I would have gone to the hospital. The next day I felt almost 100%, but my left arm ached all day. And this was just taking it once. It's not for me."
- Lis...
- Taken for 10 years or more
- November 27, 2018
For Cardiovascular Risk Reduction "I have coronary artery disease (CAD). Open-heart surgery in 2002. I have taken 20 mg of simvastatin for 16 years. The last 3 years, I have been in chronic pain. My torso, rib cage, upper back, under my arms on my rib cage, both shoulders. Deep sore muscle pain and stiffness in my back. I was diagnosed with fibromyalgia after a spine nerve test. The doctor said no fibromyalgia but myofascial. After the trigger point shot, the doctor said no to that. Help!!!! The doctors do not know why I am in pain. I have been depressed since 2014. Lately, I have insomnia, nightmares, and am extremely tired when I wake up."
- Anonymous
- December 9, 2009
For High Cholesterol "I began to have bruising around insulin injection sites; it looked like I was on anticoagulants. I am having pain in my joints, and numbness and tingling throughout my body, including my face and tongue. I have a decrease in my ability to taste food. Also, I am bruising from mild injuries with dark purple areas at the site of the bruise."
- Anonymous
- December 20, 2010
For High Cholesterol "I've used this medication for many years. I'm currently at 60 mg per day (single dose). It has done a good job, although my good/bad ratio could be a bit better still. However, I do notice muscle aches when I use it. If I stop it, they stop. They are generally not severe and not bad enough for me to stop using it. I've been told (by my doctor and others) that an over-the-counter supplement called CoQ10 can help this - I've not tried this as of yet. For people with muscle issues (check with the doctor if severe, of course), it may be worth a try (the CoQ10, I mean)."
- Anonymous
- August 6, 2011
For High Cholesterol "I take simvastatin. My level was 238 and dropped to 200 on 1 x 10 mg per day, but before the 238, I was 250. I am now on 20 mg and soon to take blood work, and no problem at all. I take it at night. I am sure it will be lower. Also, my husband had 243, and he is down to 138 on one 10 mg per day, but he moves a lot and I'm not as much. I had no side effects, and I am medicine sensitive and was scared to take it, but I am so glad I did, so try a low dose then up it if you don't have any side effects."
- tyt...
- Taken for less than 1 month
- April 6, 2018
For High Cholesterol "Feel like garbage! Actually called in sick to work one day because of how bad I felt. Blah feeling, stuffy nose, constant hot flashes, weird dreams, don't sleep. Only been on for 3 weeks and I just can't take it. Will these symptoms pass? I'm 44, 5'6", 130 lbs - it's not weight - work out like a beast - but high cholesterol and heart disease run on my dad's side - recent numbers the bad LDL keeps rising, at 200, overall number is 275 - Doctor wants to try this, but I just can't. Going to give supplements a try."
- Lou...
- Taken for 1 to 2 years
- February 28, 2021
For High Cholesterol "My bad cholesterol and good cholesterol were both low. My doctor put me on simvastatin to bring up my good cholesterol. Over the course of a year, the drug caused me debilitating leg, ankle, and feet swelling. The whole time, I never knew what was causing my swelling. I stopped taking the drug for five days, and all the swelling went away very quickly. I’ll never take it again."
- Aun...
- Taken for less than 1 month
- April 21, 2018
For High Cholesterol "I took one pill, and about 12 hours later, I began to feel very tired. 18 hours later, I went to the grocery and didn't think I was going to make it back because I became so weak and short of breath. My legs felt so heavy - almost as if I wasn't going to be able to walk. At about 36 hours after the ONE pill, I experienced an explosive bathroom episode and saw very dark stool and several drops of blood in the toilet. It's now 48 hours later, and I just put a piece of spearmint gum in my mouth and cannot taste it or smell it. One pill did this!"
- Eil...
- Taken for less than 1 month
- October 6, 2020
For High Cholesterol "Took three 10 mg simvastatin tablets... 1st night insomnia, 2nd night slept but nightmare, and 3rd night slept but woke up feeling depressed and anxious. Dr. said this wasn't from the simvastatin, but I did so quit taking it, and it took 2 weeks to feel like myself emotionally again. NEVER will I take a statin."
- brs...
- Taken for 5 to 10 years
- September 14, 2018
For Cardiovascular Risk Reduction "I am a 44-year-old male who had a stent placed in my heart 5 years ago. I was on simvastatin and have numerous side effects such as increased weight gain, extreme fatigue/tiredness, constipation, and stomach pain. Since I stopped taking simvastatin, my side effects have disappeared. I have lost weight, my energy level has skyrocketed, no more constipation or stomach pain. I am exercising and on a diet, but these seem to be working more effectively without the medication."
- Mon...
- Taken for 2 to 5 years
- March 18, 2021
For High Cholesterol "I started on simvastatin 4 years ago. During that time, I developed severe muscle pain and weakness. I also developed heart palpitations. Just recently, I missed several doses and noticed all those issues were almost all gone. I have been pain-free and feeling a lot better. It is a good medicine, but beware if you start having those issues because it may be that medicine."
- YYa...
- Taken for 10 years or more
- November 8, 2018
For High Cholesterol "This lowers cholesterol just fine. Constantly forgetting things and can't commit many things to memory since starting the drug. I am not old - started at 40, and now 50 years old. For example, I've been typing all of my adult life and since taking the drug, I have to correct typos in every sentence since my fingers do not have their muscle memory either. Events my kids say I was present at, I have no recollection of at all."
- Anonymous
- October 17, 2011
For High Cholesterol, Familial Heterozygous "Started on simvastatin about a year ago, and 6 weeks into taking the medicine, my LDL was down about 40 points. About a month ago, the pharmacy switched generics (prescription came with a heads up that the color and shape of the pill might be different). Now suddenly, I'm suffering from a swollen tongue and numbness of the tongue and upper palate. Not sure if this is due to the new generic (the pharmacist says only the filler and dye would have changed)... but it's gotten so annoying that I went to the doctor today for blood tests."
See also:
Lipitor
Lipitor is used to treat high cholesterol. Learn about side effects, interactions and indications.
Crestor
Crestor (rosuvastatin) is used to treat high cholesterol and high triglycerides in the blood ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Zetia
Zetia (ezetimibe) is used to treat high cholesterol. Includes Zetia side effects, interactions and ...
Zocor
Zocor (simvastatin) reduces low-density lipoprotein cholesterol and total cholesterol in the blood ...
Mevacor
Mevacor is used for high cholesterol, high cholesterol, familial heterozygous ...
Colesevelam
Colesevelam is used for diarrhea, chronic, high cholesterol, hyperlipoproteinemia ...
Niacin
Niacin is used to lower cholesterol and triglycerides. Learn about side effects, interactions and ...
Lovastatin
Lovastatin is used for high cholesterol, high cholesterol, familial heterozygous ...
Are you taking this medicine?
Your review helps others make informed decisions.More about simvastatin
- Check interactions
- Compare alternatives
- Pricing & coupons
- Drug images
- Latest FDA alerts (9)
- Side effects
- Dosage information
- Patient tips
- During pregnancy
- Support group
- Drug class: statins
- Breastfeeding
- En español
For High Cholesterol "Started taking simvastatin 5 days ago. I warned my doctor that statins caused cramping every time I took them. She assured me that would not be the case, she was wrong. Only 5 days, and I've lost a night's sleep and am in pain most of the time."