Zoloft for Major Depressive Disorder User Reviews (Page 3)

• notin...
• April 15, 2016

"I have had good results with 200mg of zoloft, and .5 clonazapam 3 times a day, for ten years. I've tried many ssri meds, and zoloft has been the best so far. I suffer from depression, agoraphobia, panic and ocular migraine. This current combo ( sometimes I add gabapentin if I'm still anxious about leaving my house) has been the most effective for my mood. I gained weight on paxil and getting off was a nightmare. No additional weight gain with the zoloft."

• Ruby
• Taken for 1 to 6 months
• September 29, 2021

"For months, I was struggling with anxiety and then I had a depressive episode, where I had sudicial thoughts. I knew there was something that I should do about this, so I booked an appointment with a psychiatrist and was diagnosed with Depression, GAD and SAD. While first taking Zoloft (50mg), I didn't notice any immediate changes, I was still struggling to get to school and with my racing thoughts, that would leave me in bed all day. However, as days went on I noticed I wasn't overthinking as much, my brain just felt much quieter and I noticed myself getting an interest back into things. My family even commented that I seemed much like myself once again, laughing and smiling etc. I've now been on Zoloft for about 2 months now and I only occasionally feel anxious (which is an improvement from every single day) I'm able to go to work as normal, study (and concentrate!), gym — overall, my quality of life has improved! (my sleep has also improved) Zoloft is life changing."

• Sertr...
• Taken for 1 to 6 months
• February 15, 2018

"Lifelong depression sufferer. First 3 days felt like valium, floaty and nice but symptoms were largely unaffected. Next fortnight was harrowing with vastly increased anxiety and insomnia, mind roaring the entire time. After that things chilled out a bit and life has gotten progressively easier since. First good day came at end of week 4. Now in week 7 and it's as if depression is a thing of the past, any fog thoughts are controllable and no longer dominate my outlook. Should also mention weird taste that the stuck around for the first few weeks, has either gone now or I've got used to it. Sexual desire dropped off for a while but has returned, orgasm is definitely less intense though. Weighing up pros and cons I'm functioning better than for a long time and am seeing aspects of myself that were unthinkable just 2 months ago. I'd happily stay on it forever at this point."

• KBSteph
• March 19, 2015

"Although I have only been on this med for 12 days so far. I feel wonderful. I have had severe depression due to being sick the past 3 years and nothing has been helping me get better (spinal nerve damage and severe migraines everyday) ; sometimes I just felt like I wanted to die I felt no hope.I haven't felt any side effects and my migraines are almost completely gone. I get up and do more around my house, more than ever and I am taking better care of myself. Im happy for the first time in my life. I know most people will think it's too good to be true; but really you should ask your doctor if it might be for you. I am so glad I am on this; never had a medicine work so good. Hope it last. Plus right now I have the flu and still happy!"

• Doodl...
• September 10, 2019

"I’ve been taking 50mg of Zoloft for a year and 2-3 months now. I’ve had depression for a while, and only started medication recently. Before Zoloft I was on Wellbutrin for about a year. Switched after ending up in the hospital. Both made me feel numb, which I guess is better than crying and crushing sadness all the time? Lol. Zoloft, unlike wellbutrin, has killed my sex drive. I think it helped with my depression, but it’s hard to say. I started taking it after leaving a horribly abusive relationship, so I can’t say for sure if it was the Zoloft that made me feel better. I didn’t have any side affects in the beginning, but for the past 6 months or so I’ve been feeling exhausted, all the time. Weaning myself off now because I want to try and feel joy, have great sex, and not be so tired all the time. We’ll see. It’s different for everyone, and I’ve heard many success stories. If it’s gonna keep you here and keep you goin, definitely give it a try"

• Fanni
• Taken for 1 to 2 years
• March 10, 2017

"Zoloft actually changed my life. It's helped me cope with every day situations in an non reactive way. My thoughts have calmed down and my anxiety is minimal. I've actually lost 15 lbs on Zoloft. I started on 50mg and now I'm up to 200mg per day. I've been on it for about a year now and I like that it doesn't numb everything or make me super emotional or tired. I'm very well balanced. I just wish I could sleep better."

• Izzy
• Taken for 1 to 2 years
• December 17, 2020

"Zoloft literally saved my life and wish I were exaggerating. I was in a deep depression for about 2 years, then started having manic episodes on top of erratic behavior. The first week, it felt like someone had poured cold water on my brain. I felt so relieved--- For the first month or so, I was emotionally flat, but that improved with time and I no longer have that symptom. I was started out on 50mg and now moved up to 150mg. There's no cure to depression/anxiety, and I still have episodes, but nothing compares to how I used to feel. I'll be sure to stay on this for as long as I can."

• MissM
• Taken for 6 months to 1 year
• May 27, 2022

"This medication saved my life. Before I started Zoloft my depression and anxiety were out of control. The depression was so bad it physically hurt and my anxiety kept me from leaving the house except to go to work and even that was a struggle. I had intrusive thoughts of driving my car into a tree or off a bridge every day. I noticed the benefits from Zoloft within the first couple of weeks. The first thing I noticed was it took the edge off my anxiety. I was still anxious, but it wasn't overwhelming anymore and the intrusive thoughts started to go away. My depression started to improve about 2 months in. Stick with this medication, take it every day, don't skip doses. It's slow to help, but when it does it makes a huge difference! My only side effect was a mild decrease in appetite for the first week or so."

• FLGAL
• Taken for 1 to 2 years
• April 6, 2017

"I've had a lot of success with Zoloft both as an antidepressant and for generalized anxiety disorder. It has worked for me for almost 2 years now and has really kept my symptoms under control. I'm of very small weight and sensitive to medications, so 25 mg works for me reasonably well. I have had to up my dosage to 50mg during times of high stress and it has helped so much. The only side effects I have experienced were a little nausea, some apathy, and insomnia. Other than that, I have tolerated this medication very well. It helps me put things into perspective and stops me from my having such negative, anxiety ridden thinking patterns. It helps me live in the moment and takes away a lot of my worries. I would definitely recommend."

• Anonymous
• Taken for 1 to 6 months
• March 20, 2019

"I took setraline 50 mg for two months and found myself sleeping through most of the day, decreased appetite, and no motivation. I was less social as well so not sure how my anxiety was treated by it. I cut it down to 25 mg and still found myself sleeping way too often. This wasn’t the fit for me, but when I was out of bed my friends and family said they felt I was less anxious. I just didn’t want the anxiety to come at a price of oversleeping!"

• jUSTIB
• Taken for less than 1 month
• March 21, 2015

"I've been on zoloft for almost four weeks now and it's been a life changer I use to suffer from poor impulse control anxiety and bad depression about two weeks in I started feeling better happier like.the feeling of dread has been removed the demon's are silenced I feel like I want to live I want to succeed it's like a dream come true ive suffered from drug addiction in the past and since started zoloft I don't feel the craving that overwhelming desire to get high the only downside to zoloft. Is the restlessness when.trying to sleep but it's worth the trade off I started on 50 MG and am now at 100mg per day thank god for zoloft"

• Anonymous
• Taken for 1 to 6 months
• July 30, 2022

"I promised I would share my experience to offer hope to those who might be struggling like I was. This Spring I suffered from major anxiety resulting from medical issues. When I began Zoloft at 50 mg I had so many side effects! Insomnia, tremors, muscle twitching, jittery feelings, buzzing in my extremities, night sweats and sexual side effects. I was discouraged because so many others felt better in 4-6 weeks and, while I had seen some improvement, I was no where near where I wanted to be. I started taking the medication in the morning to address insomnia and that helped tremendously. Tomorrow marks week 8 for me and I can honestly say this week has been a turning point. Side effects have reduced significantly and I now am beginning to feel like my old self. Sexual side effects remain and my doc said they would likely not improve. At some point I will likely wean off. That said, it has still helped me tremendously and I was slower to respond than others! Hang in there!"

• Anonymous
• Taken for 1 to 6 months
• November 11, 2014

"I've been on Zoloft for the past four months and it's worked great! I'd been on 3 other medications before that and none of them have worked as well as Zoloft when it's coupled with 15mg of Buspar and 20mg of Adderall. My anxiety has dropped, my mood has improved dramatically, and I've even lost weight, which I haven't been able to do since I recovered from my eating disorder. Unfortunately I think I'm going to have to have my dosage upped because of my Seasonal Affective Disorder, but otherwise it's worked very well."

• Elsaaaa
• Taken for 1 to 6 months
• May 18, 2016

"Started at 25 for about two weeks, then went to 50. Each dosage change brought back a few symptoms, but all are gone in a few days. Zoloft helped me a lot, I had never taken an anti depressant before so I was nervous. My intrusive thoughts are gone one month later!! Don't read to much into this page, it caused me to have anxiety/panic attacks. My biggest problem was swallowing, but that was due to anxiety, I didn't want to take the anxiety Meds on top of zoloft, so I just waited the attacks out, last max two hours. Just know to gradually increase your dosage and to check in with prescribing person when you have concerns. Side effects: nausea, fatigue, loose stools, blurry vision in morning, breast felt numb (gone now), dry mouth (gum!!)."

• DAT
• January 28, 2016

"For the past 9 months I have had a mixed major depressive/anxiety episode. I have started therapy from the beginning of the episode which helped me cope for a while but it was going nowhere.Finally went to see a psychiatrist last week and was put on 50mg Zoloft. Don't know if it's placebo or not but I'm already starting to feel better. My anxiety level has gone down and I'm feeling more clear minded , level headed and hopeful. The first days 4 were hell because it was making me nauseated , bloated and extremely tired and restless at the same time.On day 7 now , and I'm feeling great."

• Chris...
• Taken for 1 to 6 months
• February 17, 2021

"Been on 25 mg of Zoloft for four weeks, upped it to 50mg. Felt like I was on an amphetamine. Tried 37.5mg, and I still feel revved up in my brain. Can’t handle this drug. Some people don’t always respond well, even though the psych nurse tells me Zoloft does not create this reaction. I say everybody is different in brain chemistry."

• Anonymous
• Taken for 10 years or more
• February 19, 2024

"I took Zoloft for years and never had any problems with side effects of any kind. I had to switch to Sertraline due to the price of Zoloft. I have minor benefits with Sertraline. I still have social anxiety and more frequent sadness. So, Sertraline is okay but does not work as well as Zoloft."

• EM907
• April 5, 2016

"I'd been taking Prozac for a few years, but its effects wore off, so I switched to this. I'm very glad I did. It completely got rid of my panic attacks and obsessive worries, and reminded me how good life can be without them. I still feel sluggish, but I always have, even before I started SSRIs. The most noticeable side effects have been weight gain and erectile dysfunction. I'm going to try nefazadone and see if that works for me without the side effects. But if you don't have these side effects or they're not a big deal, I highly recommend Zoloft."

• Anon
• Taken for 1 to 2 years
• March 18, 2022

"Was on this drug in conjunction with lamotrigine for a few years as a teenager for MDD/BPD/GAD. It got rid of my sex drive, made me feel more depressed, and I slept a lot of the day away. Wasn’t for me."

• Anonymous
• Taken for 6 months to 1 year
• November 28, 2016

"Overall a very good medication. It made me very drowsy when I first started on it but this passed after a couple weeks. It did a good job of keeping me stable. I would have loved to stay on it except I ended up developing severe urinary retention that got worse as my dose increased. (By severe I mean I was unable to sleep at night because I had to get up and pee every 5 mins and almost nothing would come out) After I went off it the urinary retention gradually went away and is now completely gone. Aside from that I got no noticeable side effects from it. I would definitely recommend this med, as urinary retention is a more rare side effect and I probably only experienced it because I am known to be sensitive to meds."

• Cass
• Taken for less than 1 month
• September 14, 2021

"I’ve had intense anxiety & depression for 3 years. I put off ever taking meds because I was scared of the side effects. Then I hit rock bottom & realised I couldn’t live another day how I was. Long story short, I began Zoloft. The first week was dark. Physically, emotionally, mentally & spiritually dark. Then, on day 11, I woke up completely content. I talked to my family, laughed, hugged. Each day seemed to get 10% better than the day before. It was overwhelmingly good. My thoughts were clear. When anxious & dark thoughts or even days arise, which they inevitably do, I am able to move on. They don’t spiral & debilitate me. 3 weeks on & I am calm. Content. Happy. I socialise?!?! I feel like me again. I look back on the last 3 years & I truly didn’t realise how anxious & sad I was. It controlled my every move. Now, I feel as though I am the one in control of my life. I am so, so deeply grateful for this."

• Koala...
• Taken for 1 to 6 months
• November 25, 2014

"Zoloft is a very good medication for anxiety and depression. For me better with anxiety. I am BiPolar I, am also on Zyban 150 a day. Taking these two medications together is fine as is also taking when you are BiPolar. Only with a specialists direction, though. I have been on Zoloft a couple of times the only side effect before was severe diarrhea. This time when I started taking it I got butterflies in the stomach and flutters, but over time this unusual for me side effect left me. Some say how many weeks to feel a impact. For me this last time was around 6 weeks. Which is normal. It's been proven that any time prior 4 weeks is most likely placebo effect. But if you feel better well, whether a placebo effect or not, it's good."

• Jaws...
• July 30, 2017

"I was on this medication previously and after a week gave up hope and stopped taking it. Recently my anxiety became out of control as did my depression. I literally had no hope left. I felt sad, lonely, out of focus, irritable, suicidal, and hopeless. I would wake up having panic attacks and go to sleep having panic attacks. I started researching ways to off myself and came very close. I decided to finally seek help and while awaiting my referral to see a psychiatrist my doctor gave me this medication. I am taking 100 mg once a day. It took a week of the medicine to feel the full effects but I feel happy again, focused, grounded, and way less anxious. I find myself laughing more, joking, smiling and not constantly anxious."

• Big...
• March 4, 2017

"Developed deep depression. Resisted drugs for a while. GP recommended zoloft. First four weeks were hell then it has been excellent.The best I have felt for years. In Australia so drug very cheap. $13 dollars for month"

• JustA...
• Taken for 6 months to 1 year
• June 19, 2019

"No side effects or beneficial effects from taking this medicine. Felt severely depressed constantly. For me I still think SSRIs are just a placebo effect, since when I first took it I felt “good” but then later realised how they work hence knowing that it was just a placebo effect, from having such high expectations and not knowing anything about “antidepressants” particularly the newer SSRI..."