Rybelsus User Reviews & Ratings (Page 4)
Rybelsus has an average rating of 6.5 out of 10 from a total of 309 reviews on Drugs.com. 49% of reviewers reported a positive experience, while 22% reported a negative experience.
Reviews for Rybelsus
- Ano...
- Taken for less than 1 month
- July 21, 2025
For Type 2 Diabetes "I had been putting off taking this drug despite my doctor's suggestion because of the possible side effects and, more importantly, the cost. I finally decided to give it a try starting a week and a half ago. I haven't experienced any of the side effects mentioned in the warnings except for constipation the first three days. After that, I started having the opposite effect, meaning diarrhea. I must admit that my appetite has been curbed quite a bit. A protein shake in the morning fills me until mid-afternoon. If I do decide to eat lunch, I have no desire for dinner. Even if I skip lunch, my dinner hunger results in my eating maybe 2/3 of my usual portions, and I have zero interest in dessert later."
- cat...
- Taken for 1 to 6 months
- June 23, 2023
For Type 2 Diabetes "I have been taking Rybelsus for about 3 months. I have had nausea and weight loss. My blood glucose level is much better. It's even sometimes low. I now wear a continuous glucose monitor. I have random nausea after taking the medication in the mornings and can experience nausea during the day if I eat too much or greasy food. I think this is what causes some of the weight loss. You just don't want to eat if you have nausea. I do occasionally get a headache and constipation if I don't drink lots of water. The drug makes me not want to eat, but it also makes me not want to drink, so I have to force myself to drink water, or I get dehydrated and constipated. This drug makes me forget to eat or drink. It's strange. The good side effect is weight loss. Bad is nausea. My insurance does cover it."
Frequently asked questions
- Which GLP-1 drug is best for weight loss?
- Rybelsus vs Ozempic for weight loss: Which to choose?
- What foods should I eat or avoid when taking Rybelsus?
- How much weight can you lose with Rybelsus?
- Mar...
- Taken for 1 to 6 months
- November 28, 2021
For Type 2 Diabetes "I was on Metformin and had an A1c of 8. The doctor told me to get off Metformin and gave me a sample of 3 mg Rybelsus and prescribed the 7 mg dose after 1 month. My morning blood sugars with Metformin were 111 to 88. With Rybelsus, my blood sugar in the morning has been 148 to 208! I had diarrhea with Metformin, but that went away with Rybelsus, however, my stomach has become bloated, lots of burping, slightly nauseous, no appetite, a tightness in my chest, and now that I am using the 7 mg dose, I have become exceedingly tired with zero appetite. Today my blood sugar was 177. This is unacceptable. It was way lower with Metformin. I am quitting this. I can't be this tired and feeling so ill. I used to have energy with Metformin, but Rybelsus has completely drained it. I feel the doctor had just been visited by the Big Pharma salesman and gave her the sales pitch, and she started prescribing it. Is she getting a kickback? This Rybelsus is not good and causes cancer."
- Fat...
- Taken for 1 to 6 months
- November 9, 2021
"Weighed in at about 232 kg (507 lbs), my doctor understood my problems, both mentally and such, and weight loss without medical ways was not an option. Doctor suggested we try out Rybelsus solely for its effects on overweight people. Started out on 3 mg the first 10 days and lost about 2.5 kg, and then got upped to 7 mg 15 days later. Ten days into 7 mg, my doctor visit turned out great. I lost 8.5 kg in 25 days. Now I'm on 14 mg and do not have any bad side effects yet. The only thing I have come and go is a bit of a dry mouth. I did expect worse. From losing over 11 kg in under 35 days, I am looking forward to the coming months."
- NP2...
- Taken for less than 1 month
- July 24, 2021
For Type 2 Diabetes "28 days in! Started on 7 mg and will continue with 7 mg. I am also on Metformin 500 mg daily and have been for years. To be fair, my A1c was never above 6.3, and my weight was 179 lbs and height is 5-6. I have a strong family history of insulin-dependent diabetics, and I don’t want to go there! I’ve been losing weight like crazy with no exercise, which is why I came to read some of these reviews to see if this is common. Current weight is 164. Lost 15 lbs in 28 days! Mild nausea and dry mouth after taking the med in the morning. Pill is also bitter and not overly large, but a little hard to swallow. Nausea disappears with ginger ale or fruit. Appetite is gone! I have to force myself to eat at times. I suggest a vitamin supplement. Mild stomach ache and loose stool later in the day, but have solid soft stool in the morning. Want to continue to reach the weight goal of 155 lbs and A1c below 5.8. Then maybe go to a reduced dose if necessary. I definitely recommend this drug."
- FLG...
- Taken for less than 1 month
- May 10, 2022
For Type 2 Diabetes "I started taking the 3 mg Rybelsus pill on April 12th at 208 lbs. It is currently May 9th, and I am down to 194 lbs. My ideal weight is 165, which is probably a little low for me. I increase my dose in a few days to 7 mg per direction. I have a decreased appetite and only eat one healthy meal and drink a lot of fluids. I was nauseated during the first week of taking it, but I just took it as prescribed in the AM and waited 30 minutes before eating or drinking. I have a coffee every day in the AM. I eat my main sensible meal in the AM or at lunch. I can’t eat anything else, and to be honest, food is not my go-to any longer. I am no longer eating the white foods, but I am eating well. I walk 2-3 times a week, and I feel great. I have not had a test of my A1C, but I will at my next doctor appointment. I got a coupon from Rybelsus, and my cost went from $24 to $10. I am very pleased with this medication and not sure I need the 7 mg because I may not even want food. I also have high blood pressure, which has decreased significantly."
More FAQ
- Can you just stop taking Rybelsus?
- How long does it take for Rybelsus to start working?
- Can you take Rybelsus if you are not diabetic?
- Can you take Rybelsus at night?
- Lyn...
- Taken for 1 to 6 months
- December 18, 2021
For Type 2 Diabetes "I took 3 mg for 2 months and then started the 7 mg. The 3 mg I had heartburn, nausea, some diarrhea. Was uncomfortable but doable. But once on 7 mg, I had the same symptoms plus vomiting, constipation to the point of hemorrhoids, and severe heartburn to the point I almost went to the ER. I got out the label on this medicine, Rybelsus, and relooked up side effects symptoms on the computer. I immediately stopped on my own, messaging my doctor. Within 2 days, I felt so much better. This medicine is costly too, luckily I had insurance because I will not use this and it had to be disposed of. $ wasted."
- Mic...
- Taken for 1 to 6 months
- July 5, 2022
For Type 2 Diabetes "My first 30 days at 3 mg weren't bad. I enjoyed not feeling hungry and only experienced mild diarrhea after eating occasionally, though it wasn't triggered by specific foods, so I always needed a bathroom plan. In my last week of Month 1 on the 7 mg, I had watery diarrhea with nausea for 24-hour periods, 3 times in 10 days. I vomited one of those days. I haven't had my bloodwork checked, and I know I lost weight, but I also lost more than 3 days of my life sitting on a toilet. I ate nothing that would have triggered these episodes. Rybelsus has done one good thing - inspired my butt to get serious about my health without drugs."
- Typ...
- Taken for 1 to 6 months
- April 5, 2022
For Type 2 Diabetes "I was on Rybelsus as an add-on for my A1C control. This medication was okay at the 3 mg dose…for 2 weeks. Then when the dose was increased to 7 mg, I was nauseous every day, vomiting 4-5 times per week. I couldn’t eat, the mere thought of food or smell of food made me vomit. I ruined a day of vacation at Disney because I threw up 8 times in a 2-hour time span from this medication. It even began to interfere with my job (I’m a nurse-I can’t be throwing up multiple times a day). My A1C increased from 7.2 to 9.6 while on the medication, and I gained 8 pounds. I stopped taking it while waiting for my appointment with my provider, and I already feel 1,000 times better. I’m glad this medicine has worked for others, but I definitely don’t recommend."
- Ano...
- Taken for 1 to 6 months
- December 11, 2021
For Type 2 Diabetes "I started Rybelsus 3 mg, 7 mg, 14 mg. I was 190 pounds, and I am currently 170 lb. With zero exercise, it is expensive, but I had serious GI issues due to C. diff. I am now eating healthy, eating less, my BM movements are regular. Could not be happier. Yes, there was nausea, but you have to take this pill every morning at the same time on an empty stomach. I take it in the morning before my vitamin drinks and go back to bed for 30 minutes. Best medication ever."
- tuf...
- Taken for 1 to 6 months
- August 6, 2021
For Type 2 Diabetes "I love my Rybelsus. My numbers are so much better. I can stay in my target zone for the 1st time in years. I'm excited for my next A1C instead of dreading it. No side effects at all except pure joy. 24-year type 2. Metformin and Glipizide. I was in the high 200s to 300s. Not anymore."
- Jes...
- January 28, 2021
For Type 2 Diabetes "I am a 38-year-old woman with lupus and fibromyalgia. I was on Farxiga 5 mg twice daily, and my sugars were crazy, my A1C stayed at a 7.4, and I was always hungry. My doctor put me on Rybelsus 3 mg, I’m on day 12, and I had nausea and bloating if I ate my normal way. If I ate in moderation, I was good. Haven’t seen weight loss yet, but I like how I’m not starving all the time and glad to see the bloating stop and nausea also. Great drug. Exciting to see the results. Oh, and in November, I was at an A1C of 7.4, and now it’s a 6.4."
- Jac...
- Taken for less than 1 month
- December 24, 2020
For Type 2 Diabetes "I am 70 and was diagnosed with type II diabetes about 7 years ago. I have always been on Metformin and have tried medications like Farxiga and Janumet, both of which give me bad leg pains after a while. I started Rybelsus, 3 mg, about 6 weeks ago, and after 3 weeks felt so bad I stopped taking it. The worst feeling was quite bad lower back pain and a sort of fatigue. It was a generally weird feeling of malaise, not just fatigue. So if an introductory dose of just 3 mg is any indication, a stronger dose would be terrible for me. So now I am on the max dosage of Metformin, and my last A1c was 7.6. 7 years ago it was 6.5. I would add that at most I have been about 15 lbs overweight, and there has never been any incidence of diabetes in my family."
- kit...
- Taken for less than 1 month
- August 2, 2021
For Type 2 Diabetes "Rybelsus made me really sick. I didn't realize it until a couple of days ago. I thought I had a virus. I was practically leaning on the wall every day, trying to pull myself out of work to the car. Last week, I spent a lunch time lying on my office floor and then just left early. It is more than the nausea, it was fatigue, significant dehydration, confusion, dizziness, headaches... I'm still feeling sick after 2 days of not taking it. I just read that it can take a couple of weeks to get out of your system."
- Joh...
- Taken for 1 to 6 months
- March 7, 2023
For Type 2 Diabetes "I started with the 3 mg. Within a week, my bowel movements became loose. Other than that, it was fine. Started the 7 mg after a month. Within a week, I was nauseated constantly, along with diarrhea. The nausea got worse, and diarrhea continued. At three weeks, I had to stop taking it. The very next day, nausea stopped, and I have normal bowel movements again. I do not recommend this medication. Also, vomiting was a relief a few times."
- ric...
- Taken for 1 to 6 months
- December 28, 2021
For Type 2 Diabetes "I've been on Rybelsus for a little over a month for PCOS and have had an overall positive experience - just started the 7 mg dose. My doctor recommended it since I am at risk for type 2 diabetes (>30 BMI, borderline high fasting glucose with a normal A1C, and signs of insulin resistance from PCOS). I get some pretty extreme nausea whenever I eat junk food (fatty and/or sugary), but otherwise feel good. I'm hoping that the nausea I do get helps instill better long-term eating habits. I've also experienced appetite suppression, which has helped me prioritize proteins and vegetables. I did get alternating bouts of constipation and diarrhea when starting this medicine and am expecting that I'll experience the same with the dose increase. I have felt far more energy, and my cravings for junk food have drastically reduced. So far, I've lost slightly more than 10 lbs and am shooting for another 50 to help get my PCOS under control."
- Sti...
- Taken for less than 1 month
- November 9, 2020
For Type 2 Diabetes "My doctor had me on another medication, but felt that this would work better for me (I was having success with the other medication). I’ve been on Rybelsus for a little more than two weeks now and I have not experienced any of the side effects. However, I have been eating everything in sight and have gained weight. I’m feeling hungry and snacking more. My previous medication suppressed my appetite and I felt full and satisfied after eating. I think my medication was changed because it was new, and the doctor could make a few extra bucks prescribing it."
- Her...
- Taken for 1 to 6 months
- January 30, 2021
For Type 2 Diabetes "Was on 3 mg Rybelsus for a month. Nauseous all the time. After a month, went on to 7 mg for a month. Nauseous all the time. After a month, moved on to 14 mg. Nauseous all the time... This drug is awful."
- Ann...
- Taken for 1 to 6 months
- April 7, 2023
"I started this medication on Dec 20th, 2022, 3 mg when my doctor told me I was diabetic. I weighed 206 lbs. A1C 6.5. The first month on this, I was nauseous and felt sick. At 30 days, I told him what I felt. He said, 'I am putting you on 7 mg now. Your body will get used to it.' Here I am now, 3 months later, and I am so sick. I get nauseous still, have constipation, diarrhea, and loss of appetite, and the smell of food at times is so nasty. I am constantly feeling sick, dizziness, and I feel lightheaded, always exhausted, no energy, which scares me. My A1C is lower now, 6.1. I have pretty much stopped having sweets, carbs, or anything bad. Weight loss is out of control. My current weight is 157 lbs today when I went to the doctor. I have lost 49 lbs in 4 months. I told him I can’t take this anymore. He changed me to metformin 500 mg, let’s see how this one works. This medication hurt me more than it helped me."
- AK0...
- Taken for 1 to 6 months
- July 14, 2025
For Type 2 Diabetes "I have been diabetic for the past 15+ years. My A1C for the past year has been around 8-9, and my doctor put me on Rybelsus 3 mg to try along with 1500 mg Metformin (which I was already taking). The initial few days were horrible. Had constipation, bloating, and vertigo problems. I had to change my eating habits and maintain discipline of eating only 3 times. Every time I have anything between meals, my nausea returns. I also do brisk walking for 30 mins, 3-4 hours after lunch. I am also using Freestyle Libre 3 to monitor my sugar all the time. Walking helps maintain my sugar levels in range. After 4 months, my A1C came down to 7.8. My doctor has increased the dosage to 7 mg. With 7 mg, my sugar levels seem to be much better than with 3 mg. Waiting on my next visit with the doctor to check my A1C and hoping to be below 7 (target set by doctor). Will update this post after my next visit and share results."
- Mik...
- Taken for 1 to 6 months
- June 9, 2024
For Type 2 Diabetes "Short story is this drug worked for me! 242 lbs Started 7.4 A1C. 3mg Rybelsus. I was really trying hard. Fast food I cut and was exercising 3 days a week. I have a sweet tooth and my wife is a great baker. She had something ready for me all the time. Sunday doughnut trips. Dairy Queen etc. Cut but not cut all out. 30 days later I did lose some weight. A1C 7.0. The Doc told me the prescribing was 3mg for 30 days then 7mg. I did exercise 4 days a week and cut the sweets some more (that was hard lol). Then the magic happened. In 150 days from start 3mg to 7mg, my A1C 5.1, 195 pounds. 5 more to go. I'm 6 ft tall. I was a fat boy at 242. Now all my old clothes fit with a belt. I know this drug won't work for everyone. However, it worked for me. It will work for you if you try hard. Don't just take the drug. I do get an upset stomach from time to time but worth it!"
- Dav...
- Taken for 6 months to 1 year
- August 23, 2024
"I started using Rybelsus in October of 2023. My starting dosage was 3 mg, and then raised to 7 mg about 4 months later. I have encountered redness, hives, and itching on my calves, scaly skin, diarrhea, constipation, nausea, cramping, and dizziness. Most of those symptoms have gone away. I take it each morning alone and do not take anything else for at least 30 minutes. When I get to work, an hour later, I take my heart and blood pressure medicine (for Afib). I gained a lot of weight for multiple reasons. The main reason was because of depression and chronic back disease. I just had lower back fusion, which has stopped my back pain. This means I can exercise now without severe pain. The good news: since I have been taking Rybelsus, I have lost 70 pounds. I now weigh 330, and by January 1, 2025, I want to be 299. It works, but does have side effects. The key is using it as directed and learning to eat smaller, healthier food portions."
- Dud...
- Taken for 1 to 2 years
- November 8, 2024
For Type 2 Diabetes "Lost too much weight, lost my appetite for food and life, until my diabetic nurse told me to stop the tablet at once. I had to go to A&E with a UTI, but while there they told me to see my GP and get a two-week referral. I looked so ill they thought it was cancer. Thankfully, it was not cancer. I’ve been off Rybelsus for three weeks and I am eating normally and feel much better. I believe in all honesty it would have been a close thing between me and death."
- Mik...
- July 10, 2021
For Type 2 Diabetes "Well, I am on month 2 of Rybelsus and on the 2nd week of 7 mg. I posted my experience last month as well. I am 20 lbs overweight and pre-diabetic for many years. Diabetes runs in my family. I am 60 years old, active, and healthy otherwise. Unfortunately, I do not experience much of anything toward my goal of weight loss. I am slightly nauseous at times. I am constipated. I am not on any other diabetic medication. I weigh 1 lb less, but this could be attributed to a margin of error. I am planning to continue using this medication and see what happens once I am on 14 mg. Considering all the potential serious side effects (thyroid cancer, pancreatitis, and more), this needs to give anyone better results. I believe that people respond differently to everything, so great for those who do well on Rybelsus. See you next time with better news. Stay safe."
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For Type 2 Diabetes "My doctor gave me a sample box of 3 mg Rybelsus for T2D. I could only tolerate it for 10 days. The first thing I noticed was my appetite was gone. As days went on, I felt like I was in my first trimester of pregnancy, although I didn’t ever feel like vomiting. Continuous nausea, lack of appetite, lethargy, and horrible constipation were my friends during the time I took the drug and for about a week afterward. I ended up in the ER with terrible IBS with very painful cramps. I thought I had a blockage from no BMs for 12 days. After being off the drug for about a week, one day I woke up and the symptoms were gone (about a week after I stopped taking it). I felt like myself again. During that short time period, the pounds just started melting off me, and I only weighed 138 going into this. I dropped down to 130. I really wanted this drug to work for me. My doctor tried to prescribe Trulicity after this. No way. It’s too similar. My A1C is 8. Not sure where to go from here."