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Rybelsus User Reviews & Ratings (Page 2)

Rybelsus has an average rating of 6.4 out of 10 from a total of 283 reviews on Drugs.com. 48% of reviewers reported a positive experience, while 24% reported a negative experience.

Reviews for Rybelsus

Commonly mentioned side effects
  • Sue...
  • Taken for 6 months to 1 year
  • July 25, 2021

For Type 2 Diabetes "I started this 7 mg along with 1000 mg of Metformin in August of 2020, and I have lost over 65 pounds. I was insulin resistant and could not lose weight regardless of my diet. I’m 56 years old, and this has been the easiest weight loss I have ever had, and I have done it all. I did begin with a low carb diet, but now I eat what I want in moderation. It has definitely helped with my appetite, and I feel full quickly. I am under a doctor's supervision and go monthly, and all of my numbers are great. It may not work for everyone, but for me, it’s been a lifesaver."

10 / 10
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  • Bun...
  • Taken for 1 to 6 months
  • October 11, 2020

For Type 2 Diabetes "I have read a lot of the comments. This medication has helped lower my A1C. I am down from an 8.1 to a 6.5. When I started it, I was weighing 238 pounds, now I weigh 217. I was wearing a size 18W/20W, now I am at size 16W. I don't want to get too small. I like the way my clothes fit on me. The only thing that I have read about taking this medicine is that it can cause Thyroid cancer. So I may stop taking it."

10 / 10
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  • Mis...
  • Taken for 6 months to 1 year
  • August 14, 2020

For Type 2 Diabetes "Started Rybelsus when it first came out in October 2019. Took 3 mg at first and my glucose levels started to rise. Changed to 14 mg and was on that for 6 months. Glucose went very low - I was tired and weak. A1C went from 10.1 to 5.2. Changed to 7 mg and feel so much better, glucose levels are still within normal limits. I've had no side effects and great results. I do take this with 5 mg of Glipizide - once a day. Have tried many diabetic drugs and Rybelsus has worked the best. I've had a slight weight loss... under 10 lbs. So glad I tried this drug. It's a winner in my book."

10 / 10
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Frequently asked questions

  • Isa...
  • Taken for 1 to 6 months
  • September 24, 2020

For Type 2 Diabetes "My endocrinologist prescribed 3 mg to start because the B12 depletion from metformin (I have B12 anemia) was not good and constant yeast infections from Forxiga were very annoying. At first, I noticed a major appetite decline. There was a bit of nausea for the first 2 weeks. I started the 7 mg after a month and while I've been experiencing constipation, I am so happy about the weight loss. I've been on Rybelsus for 10 weeks and have lost 10 lbs. My latest random glucose test had me at 5.7, down from 6.3 - 7 over the previous few months. I am happy about fewer carb cravings and will stay on Rybelsus as long as I can. I am lucky my health plan covers it because it's quite expensive."

10 / 10
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  • Psy...
  • Taken for less than 1 month
  • September 28, 2020

For Type 2 Diabetes "Started on Rybelsus 20 days ago after I went in to see my doctor and my A1C was 11. This is while I was also taking pioglitazone and 2000 mg of metformin. After being on it for only 20 days, it has brought my blood sugar average down from 269 to 131. My 14-day glucose is 114, and my 7-day average is down to 109. I am hopeful that my next A1C reading will be 5.6. I did notice a little looser stool when I started it, but nothing worse than when I started Metformin. So far, so good. My only complaint is how expensive it is! I may not be able to continue it because of the cost."

10 / 10
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  • Ash...
  • May 12, 2021

For Type 2 Diabetes "My endocrinologist prescribed this to help with PCOS. I weighed 211 lb and started on 3 mg and lost 6 lbs while walking for 2 miles a day most days for a month. I was bumped up to 7 mg, but insurance wouldn't cover it, and I ended up gaining the weight back after trying Victoza and Byetta. My insurance changed, and my endocrinologist started me back on it at 7 mg since I already had Byetta in my system. During this time, I found out I have Ehlers-Danlos and was recommended to start weight lifting to help strengthen my muscles and lost 13 lbs in a little over a month, which I'm sure exercise has helped contribute. My menstrual cycle has been regular and on time for the first time in 4 years. I haven't had any major side effects other than a little nausea when I first take it in the morning and diarrhea, but I had that issue beforehand. I know a lot of people have said the side effects are terrible, but it hasn't been for me, and you should certainly give it a try. It's honestly been wonderful."

10 / 10
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  • Ali...
  • Taken for less than 1 month
  • August 16, 2020

For Type 2 Diabetes "I have been exercising, dieting, counting every calorie, weighing food, and meal prepping. No weight loss and fasting blood sugar is still over 160 after 24 hours of fasting. I tried metformin, I got diarrhea, but no weight loss and no decrease in appetite. I need to lose 30 lbs and have lost 8 by skipping breakfast, having lunch, and skipping dinner some days. If I eat before 5 pm, I don't get reflux and I sleep better. I am having night sweats, but I'm 56, so I'm menopausal. I'm not taking hormones. I increased the dose to 7 mg and had diarrhea for 3 days, I'm now up to 14 mg on an empty stomach. No more diarrhea, and I have energy. I am 142 now and trying to eat healthy, but mostly eating no more than the size of my fist and staying as active as I can. I'm feeling cravings go away."

10 / 10
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More FAQ

  • owl...
  • Taken for 6 months to 1 year
  • April 26, 2021

For Type 2 Diabetes "I've been on Rybelsus for eight months, and I have lost about 34 lbs. I started on the 3 mg dosage, and after two months, moved up to 7 mg, where I have stayed. However, one of the major side effects is slowed gastric emptying, which can lead to extreme stomach pain if you make the mistake of eating too much in a day. After a couple of bad episodes, I had an endoscopy just to be sure nothing else was wrong - but ultimately, my gastroenterologist said that it's just the effect of Rybelsus."

8 / 10
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  • Jer...
  • Taken for 1 to 6 months
  • June 20, 2023

For Type 2 Diabetes "It was a disaster for me. My A1C used to stay between 7.5 and 8.5, and morning fasting readings were high, like 130 to 160. Increasing Glimepiride from 4 mg up to 8 mg didn't work. My doctor started me on 3 mg/day of Rybelsus. It caused constipation, upset stomach, and a lot of burping. But morning fasting readings came down to around 100, so I was tempted to try it out. After finishing the 3 mg dose for 30 days, I started taking 7 mg/day. My symptoms worsened: constipation, loss of appetite, noisy stomach, lots of burping, GERD, and weight loss from 152 lbs to 139 lbs in just about a couple of months. I could not afford to lose any more weight. I also saw some foamy urine indicating it was affecting my kidney function too. I stopped taking Rybelsus under my doctor's advice, and since then, the constipation is gone, the burping is gone, the appetite is good, and life seems back to normal. I still need to check on my kidneys for any issues since foamy urine is still there. The last A1C was 7.9."

1 / 10
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  • SSH...
  • Taken for 1 to 6 months
  • February 25, 2020

For Type 2 Diabetes "I have been on Rybelsus for 2 months. I started on the 3 mg and did fine, no side effects, and actually felt more awake and focused. Then I went to the 7 mg and was very nauseous and vomited almost nightly. It felt like my food never digested. I apparently am pretty sensitive to this medication and since my blood glucose and A1C have been good, I am taking this every other day, which has lessened the nausea and discomfort. I have lost 6 lbs in the past month and that has been great because I needed that. So we will see how this continues, but I feel pretty good."

9 / 10
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  • L0v...
  • Taken for less than 1 month
  • March 14, 2020

For Type 2 Diabetes "Second day on Rybelsus 3 mg. I was too afraid to try it, but I'm glad I did. No side effects at all except for the loss of appetite. I will return and provide an update. I need to lose 60 lbs. I have tried Victoza and Invokana and got very sick within the first couple of days of taking them, so I hope Rybelsus is the answer for me. I exercise and watch my diet, but my glucose levels were still too high."

10 / 10
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  • JJa...
  • Taken for 1 to 6 months
  • April 29, 2021

For Type 2 Diabetes "This is the first medicine I've used that has actually helped me lose weight. I take a bunch of psych meds that have packed on pounds (Seroquel). I started with the 3 mg titrating package and had slight heartburn for a few days. By the end of a month on 3 mg, I lost ~6 lbs. I had slight nausea at first on the 7 mg dose (after a month on 3 mg), but that faded. Now, after a month on 7 mg, I'm down a total of 14 lbs total (233 to 219). Before this med, I've been trending only upward for the past 4 or 5 years. I'm super stoked that I might be able to see under 200 lbs again in a few more months."

10 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • March 28, 2025

For Type 2 Diabetes "I started in 3 mg, now in 7 mg. My blood sugars have come down enormously, I have lost about a stone in weight after being on it for 4 months. You must take it first thing with just a dash of water, don’t eat or drink for half an hour. The side effects are a bit brutal but do die down, bit of constipation and food suppression. Feel better than I have in a long while on this tablet."

7 / 10
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  • Bir...
  • Taken for 1 to 6 months
  • August 12, 2020

For Type 2 Diabetes "Bad news: I started taking the 3 mg Rybelsus for 30 days, did well. Have been taking the 7 mg for the past 3 weeks, and I have had diarrhea, stomach bloating, nausea, and can barely eat anything or drink. Even the smell of food makes me sick. I am extremely exhausted and hate feeling like this. Calling doctor tomorrow. Good news: dropped A1C from 8.4 to 7.3 in 6 weeks and lost 10 pounds, and also cut back on my 24 hr insulin and fast acting due to not eating. — Is it really worth it though???"

3 / 10
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  • Pau...
  • Taken for 1 to 6 months
  • May 21, 2023

"I take this for weight loss. I have lost 1 stone exactly after 7 weeks on Rybelsus. I am due to increase to 14 mg in the next week or so. I am so thrilled and have gotten back into my size 12 jeans today. I have next to no symptoms, occasional heartburn, a sudden disliking for my morning coffee, and the occasional mild feeling of being full. I eat less than 1,400 calories a day with ease. I can't tell you how happy I am to finally have a BMI of 25 for the first time in a decade exactly. I drink wine every weekend, but all my cravings have gone, and I rarely finish anything. I rarely feel hungry and am no longer obsessed with food. I feel so well. Obesity is so damaging and a serious health risk. I am finally a healthy weight. Going to aim for a BMI of 22.8, or weight of 9 st 3 lbs, which is what I weighed before having children... I'm so thrilled... well worth the £170 I pay per month."

10 / 10
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  • Rit...
  • Taken for 1 to 6 months
  • January 17, 2020

For Type 2 Diabetes "For the first three weeks on this drug, I had oscillating constipation and diarrhea. I felt very nauseous and did not want to eat much. After upping the dosage, the digestive problems have decreased, but I still feel nauseous and don't have much of an appetite. I have been on it since November and have lost 16 lbs. with Metformin, diet, and exercise."

5 / 10
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  • Cla...
  • Taken for 1 to 6 months
  • December 12, 2020

For Type 2 Diabetes "I just got my A1C after 3.5 months on Rybelsus (one month at 3 mg and 2.5 at 7 mg), and I’m very excited that it’s dropped from 7.8 to 6.5! I have had some side effects - mainly stomach pain, gas, and occasional constipation - but the results are worth it. I haven’t had any significant weight loss, but my BMI was under 27 to start with, and because we had Thanksgiving recently, I normally would have gained a couple of pounds. If you have just started and are having side effects, try to hang in there. The first month was the worst for me."

8 / 10
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  • Car...
  • Taken for 1 to 6 months
  • March 19, 2022

For Type 2 Diabetes "Using Rybelsus was a nightmare for me. I have insulin resistance, and my doctor wanted to bring my A1C down below 6. First, it caused me to gain 10 lbs while I was on the 3 mg. I thought once I started the 7 mg, the weight would finally start to come off. Nope. If that wasn't bad enough, I was lucky enough to experience one of the rare side effects... nerve damage. My left leg started feeling like I had sciatica. It got a lot worse from there. Nerve damage not only affects the damaged area but your brain as well. It took about 4 months before I began to feel normal. I had quit the Rybelsus as soon as I realized what was happening to me. My annual family vacation was ruined. I had an extra 10 lbs on me. I couldn't drive for a couple of months, and my brain was seriously affected. Oh yeah, and nerve damage is like pain I never felt before, and I've given birth twice. I'm glad for the folks helped by this. It sure didn't work out for me."

1 / 10
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  • Big...
  • October 7, 2020

For Type 2 Diabetes "I started taking Rybelsus for weight loss. I was 326 lb. Now that I have been on it for a month, I have lost 8 pounds. I’m 318 lb currently. I have had absolutely no side effects. I’m a 6’1", 22-year-old male. I am not sure if that factors into anything. Anyway, tomorrow I’ll be starting to take 7 mg, then hopefully next month 14 mg, and so on."

10 / 10
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  • Cha...
  • Taken for less than 1 month
  • October 16, 2020

For Type 2 Diabetes "I am on the 23rd day of the 3 mg dosage. Looks like most of the reviews have the same common denominator: nausea, bloating, diarrhea, and I’m about to add myself to the list with those same side effects. I’ve lost a few pounds, and my glucose numbers are dropping. I don’t like being too nauseous to want to eat, but underneath, I feel very hungry. I’m hoping this will resolve itself, and maybe it’s just an adjustment. Otherwise, I might have to rethink this."

8 / 10
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  • mym...
  • Taken for 6 months to 1 year
  • September 17, 2021

For Type 2 Diabetes "I was started on Rybelsus 3 mg in March and went to 7 mg in April. The first two months were an adjustment. It totally curbed my appetite. I have a feeling of being full most of the time. I have noticed I am eating basically half of what I did before. My A1c went from 7.2 to 5.8, and I have lost a little over 20 pounds. Even with insurance, it is a little expensive, but then I found the manufacturer coupon on the Rybelsus website, and that helps tremendously. So far, I am very happy with this medication."

10 / 10
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  • Lir...
  • Taken for 1 to 6 months
  • July 25, 2020

For Type 2 Diabetes "Unfortunately, I had serious issues with this medication, Rybelsus. If you have any gastro disease, please do not take it. It started okay, but initially, I developed symptoms: sore throat, trouble swallowing, burning, tight chest, nosebleeds. I felt like my breathing tract was on fire. I have a hiatal hernia, and unfortunately, the amount of acid reflux due to this medication was beyond anything I could tolerate. I tried for 48 hours till I broke and stopped. All symptoms went away afterward."

4 / 10
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  • Nor...
  • May 23, 2021

For Type 2 Diabetes "I started taking Rybelsus around March 10 or so. I did the 3 mg, the 7 mg, and now am on the 14 mg. I am still very nauseous, but I am trying to figure out the best way to take the medicine. I find that I eat half the food I did before. I don't have much of an appetite. What has also helped me (tremendously) is getting a Freestyle Libre - I am able to check my blood sugar throughout the day and can see my peaks during the day. I had not weighed myself until this week, I had lost 6 lbs. I am an avid exerciser, but that and the way I have been eating have not helped me lose weight. I am very glad to see that I am losing weight because I have not been able to lose anything despite the exercise. I never knew what diet control was until I got the Freestyle. I can't believe the difference. Can't wait to go back to the doctor and get my A1C. Thanks for sharing."

9 / 10
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  • Mik...
  • Taken for less than 1 month
  • June 16, 2021

For Type 2 Diabetes "I am on week 2 with Rybelsus. I started week one with 3 mg. No side effects, no weight loss, slight nausea, and greater appetite. I need to lose 20 lbs, and instead, I am hungry all the time. Called my doctor. He told me to double up on the 3 mg, bringing it up to 6 mg. Still, no side effects, very slight nausea, but increased appetite. Ugh! I want it to work so much. I will stick to it and see what happens."

5 / 10
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  • ATQ...
  • Taken for less than 1 month
  • March 13, 2023

For Type 2 Diabetes "I took my fourth dose of 3 mg Rybelsus this morning. I've followed all the directions, but it has been awful. I've been incredibly sick since the second day. I've been vomiting, nauseous, I've had a nonstop migraine, and every time I cough, vomit, sneeze, or gag, my entire upper body feels like it's being electrocuted. I emailed my doctor last night. Hopefully, I'll hear from her today. This is miserable."

1 / 10
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