Rybelsus and Nausea: What Users Say (Page 5)

• Esa...
• Taken for 1 to 6 months
• July 28, 2021

For Type 2 Diabetes "My doctor advised me to start with 3 mg for two to four weeks. She suggested if I was good at two weeks to up to 7 mg dose. I have been on 7 mg for 3.5 weeks and feel nauseated more often than not. I also bounce between diarrhea and constipation. Not sure how much longer I can do this. How long before these side effects lessen?"

• Car...
• Taken for 1 to 6 months
• June 8, 2023

For Type 2 Diabetes "I was offered this by the pharmacist at my local GP practice. I'm borderline diabetic and have been taking Metformin for about 5 months now. I've been overweight for over 30 years, and only calorie-restrictive diets have worked - generally 600 to 800 calories a day. This hasn't been a problem for me as I have a very low appetite naturally and have always struggled to finish a single course. I was told Rybelsus would help both the diabetes and have a positive effect on weight loss. Every morning, I have religiously taken it as prescribed for 3 months. I'm now on the max 14 mg dose and struggling with extreme nausea for about an hour after taking it. I also have burning indigestion for 30 mins, which is hard to cope with given you can't guzzle water to try and settle it. I have lost 2 lbs in 3 months. My appetite is so absent I've been advised to take vitamin supplements. Considering giving up and going on a 'real' diet with the side effect that it'll address my mild diabetes."

• fil...
• Taken for less than 1 month
• October 11, 2022

For Type 2 Diabetes "Already 3 weeks Rybelsus 3 mg, the nausea is sometimes still present, more appetite especially in the morning, while eating a little less appetite, weight goes up instead of down. I have already gained 4.5 kg, are there still people with this problem? I am in despair."

• Jen...
• Taken for 1 to 6 months
• June 2, 2022

For Type 2 Diabetes "I was prescribed Rybelsus for weight loss. Started with a month at 3 mg and have been up at 7 mg a little over a month now. It totally suppresses my appetite, and I have already lost weight without counting calories or 'dieting' in any way. I have had a lot of nausea, and it isn't gone yet. But it isn't terrible, just a nuisance."

• Txg...
• Taken for 1 to 6 months
• January 4, 2023

For Type 2 Diabetes "A1c crept up to 6.9. Started Rybelsus for a 30-day intro with fairly vague side effects of light nausea, constipation, and reduced appetite. Increased to regular 7 dosage and immediately side effects were extreme and awful. Constant significant nausea, abdominal discomfort, significant constipation, low energy. Almost no desire to eat, and if I did eat, even very little food caused even more discomfort that escalated. Food just sat in my stomach feeling heavy and sour. Heartburn and gas were constant. After just 5 days of a larger dose, I stopped the medication but with lingering side effects. After being off the drug for two days, I sustained immense abdominal pain like I have NEVER experienced that finally culminated in strange diarrhea. Too many intense and questionable side effects for me. Weight loss - by not being able to eat - not worth the escalating horrible side effects for me. I'll never take this drug again."

• Lou...
• Taken for less than 1 month
• May 11, 2022

For Type 2 Diabetes "I've been on this now for nearly 2 weeks. To help reduce blood glucose levels and boost my weight loss. I've lost 1 lb and have a loss of appetite, also nauseous most mornings if I don't eat after 30 mins of taking meds. Today I ate 2 biscuits with a cup of tea and vomited really bad, which I'm sure is related to this medication. As I feel absolutely fine now. Seems the side effects are the same as the majority here. I'll stick it out and increase the dose in 2 weeks."

• Pet...
• Taken for 1 to 6 months
• February 24, 2022

For Type 2 Diabetes "The benefits were great: low sugars and low appetite. Lost 10 in 3 months. However, I had side effects that did not go away: nausea, diarrhea, abdominal pain with gas. It became too much, and I stopped taking Rybelsus."

• Tis...
• Taken for 6 months to 1 year
• May 22, 2025

For Type 2 Diabetes "Year this month, still get constipation but use natural remedies to help. Lost 2st so far but slowly also sugars resist so much better and cholesterol. Can’t walk very well although only late 70s. But yes, prefer this to injections. Have had nausea but it gets less as time goes on on bouts of diarrhea not at all often. My bugbear was constipation but hoping natural remedies will work although have powders from doctor prefer natural if possible."

• Jrc...
• Taken for 1 to 6 months
• August 19, 2022

For Type 2 Diabetes "I’m worried because with Rybelsus 3 mg for a month, didn’t lose any weight, but nausea and barely eating. Now at 6 mg because I’m doubling almost a month with, now, lost only 1 pound. My worry is that I’ve been having sudden kicks in my legs, tingling, like neuropathy, still nauseated, constipated, and my stomach most of the time with heartburn and acid reflux. Should I stop? I don’t even have diabetes, just pre-diabetic."

• gra...
• Taken for 2 to 5 years
• May 29, 2025

For Type 2 Diabetes "I am older and without the strength to open the bottle. I have found if I turn it upside down and hit the bottom with a hammer a couple of times, it opens easily. After using Rybelsus a few years, I have developed more side effects, constipation, sleepiness, and nausea, but I'll work through it because this drug keeps my diabetic levels perfect."

• Ano...
• Taken for 1 to 6 months
• June 9, 2025

For Type 2 Diabetes "It has definitely controlled my diabetes. I hate the nausea every day and not being able to finish a meal. I can no longer stomach alcohol but have sugar cravings. Also, a lot of cramps usually in my feet every day, but also my legs at night."

• And...
• Taken for 6 months to 1 year
• September 21, 2024

"In 6 months of use, I've lost 17 lbs, and I feel better than I have in many years. It causes a small amount of nausea at the beginning, but it was tolerable. The main effect has been a reduction in appetite, which in turn has made me make better food choices."

• Lau...
• Taken for less than 1 month
• January 4, 2025

For Type 2 Diabetes "Positive results: it did help lower my sugar. It shut the 'food-obsessed voice' off in my head, and I had a reduced appetite. Lost weight. BUT...as the week progressed, I was nauseous and vomited frequently. Just miserable."

• AK0...
• Taken for 1 to 6 months
• July 14, 2025

For Type 2 Diabetes "I have been diabetic for the past 15+ years. My A1C for the past year has been around 8-9, and my doctor put me on Rybelsus 3 mg to try along with 1500 mg Metformin (which I was already taking). The initial few days were horrible. Had constipation, bloating, and vertigo problems. I had to change my eating habits and maintain discipline of eating only 3 times. Every time I have anything between meals, my nausea returns. I also do brisk walking for 30 mins, 3-4 hours after lunch. I am also using Freestyle Libre 3 to monitor my sugar all the time. Walking helps maintain my sugar levels in range. After 4 months, my A1C came down to 7.8. My doctor has increased the dosage to 7 mg. With 7 mg, my sugar levels seem to be much better than with 3 mg. Waiting on my next visit with the doctor to check my A1C and hoping to be below 7 (target set by doctor). Will update this post after my next visit and share results."

• Jea...
• Taken for less than 1 month
• October 14, 2022

For Type 2 Diabetes "The worst experience ever on a medication. Nausea, bad heartburn, weak. Most likely dehydrated, I could not eat or drink anything. Food was my worst enemy on this medication. I would have ended up anorexic. Sugars went down, but that's because you can't eat, and then I had many low sugar readings. I went off it."

• Tat...
• Taken for 1 to 6 months
• February 9, 2021

For Type 2 Diabetes "I've been on Rybelsus since November 1st, 2020, for type 2 diabetes / a dose of 7 mg. I have occasional nausea, but overall, it's amazing. I lost 33 pounds in 12 weeks, and I feel better than ever."

• Her...
• Taken for less than 1 month
• November 14, 2020

For Type 2 Diabetes "I started Rybelsus 3mg a week ago. Started out okay, but man oh man, I am feeling nauseous as anything now. Hopefully, it goes away. I am actually scared that I need to move up to 7mg."

• Kat...
• Taken for less than 1 month
• April 2, 2020

For Type 2 Diabetes "On Rybelsus, after day 4 of 7 mg, I took to the bed with nausea. I will not return to this medication."

• Gra...
• Taken for less than 1 month
• June 12, 2024

For Type 2 Diabetes "Using a very low dose as I could not handle the shots. Minimal nausea, weight stable and still losing. My sugar does drop more rapidly. I have to check more often."

• DCa...
• Taken for less than 1 month
• March 16, 2021

For Type 2 Diabetes "I've been on Rybelsus, 3 mg, now for exactly a week. My blood sugar morning count has increased a lot. Headache and sick to my stomach. I have a call into the doctor's office for advice."

• bcs...
• Taken for 1 to 6 months
• April 17, 2025

For Type 2 Diabetes "I tolerated the 3 mg course. I'm 12 days into the 7 mg pills, and I've had nausea, dizziness upon standing, and tired for the last four days. I'm getting ready to email my doctor for his advice."

• Ryb...
• Taken for 1 to 6 months
• October 17, 2024

For Type 2 Diabetes "Very good results. Dr. originally prescribed Synjardy, and it had awful side effects: dizziness, nausea, stomach pain. It was totally debilitating."

• MDG...
• Taken for 1 to 6 months
• March 24, 2025

For Type 2 Diabetes "Went from 3 mg to 7 mg to 14 mg. At 14 mg, severe abdominal pain and nausea. Went back to 7 mg. Not as bad as the 14 mg level, but still have some nausea and stomach pain to a lesser degree."

• Dun...
• Taken for 1 to 6 months
• September 15, 2024

For Type 2 Diabetes "3 mg did not have any effect. Used to 7 mg. Had a couple weeks of nausea, no weight loss as yet. Some lightheadedness and instability occasionally. Still at 7 mg. Almost three weeks now."

• stu...
• Taken for 1 to 6 months
• May 19, 2025

For Type 2 Diabetes "Okay with 3 mg, okay with 7 mg, now 14 mg, feel nausea, appetite almost gone. Having a real problem with heartburn. Trying to live with it, my A1C has gone from 10.4 to 6.2 in a few months."