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Quetiapine for Borderline Personality Disorder User Reviews (Page 4)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.6 out of 10 from a total of 127 reviews for the off-label treatment of Borderline Personality Disorder. 66% of reviewers reported a positive experience, while 9% reported a negative experience.

Reviews for Quetiapine

  • CJmck...
  • September 23, 2013

"I have been taking quetiapine for 4 years now for Bipolar Disorder and Borderline Personality Disorder and I have found them very effective in my treatment. I have however also been taking lamotrigine, fluoxetine for my bulimia also and promethazine. I do struggle with sleep, etc. but the problems aren't as severe."

10 / 10
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16 Report
  • so...
  • Taken for less than 1 month
  • August 28, 2023

"I've only just started this medication. I get severe anxiety starting new medication because of side effects. I am worried about the weight gain, but honestly, I could use a little more weight. I started on 25 mg at night. I was taking trazodone, but I don't need that since the Seroquel literally knocks me out lol. I am drowsy the next day; hopefully, that will subside. But seems like my intrusive thoughts have disappeared overnight and I'm not aggravated by other people. Before I started taking this drug, I was in fear for my life as well as my kids. Which is what pushed me to try something. Anything at this point to where I would stop having horrible nightmares of hurting myself or others. I'll be back to write another review in a couple of months, but as of now, it's a miracle drug. Especially for sleep and slowing down my brain, which normally seems like the guy in the movie flash. Feels weird to feel somewhat normal, especially for only being a week."

10 / 10
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  • Kxopld
  • September 22, 2017

"20 yrs old- diag with BPD, ICD (impulse control disorder), depression, anxiety, PTSD from childhood sexual assault & rape when I was 14. I was prescribed Q for the BPD impulse & for bad flashbacks I was having in my sleep from PTSD. I was also prescribed Lamictal for my depression & for mood swings. I LOVED taking them together. I felt like a normal person...the only thing was that Q made me feel kinda groggy some days but hey I'll have some coffee & get over it. It's better than the way I was feeling b4. A yr or so later I had stopped taking them because I felt good and wanted to live w/o meds(I know, bad idea.) Now here I am again needing medicine & I have no health insurance so I'm using just the Q I have & it's not the same by itself :/"

7 / 10
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11 Report

Frequently asked questions

  • Gee
  • October 30, 2019

"I’m on 150mg of this twice a day, depending on daily moods I sometimes take more (although I shouldn’t). I find it really helpful for the list of mental problems I have, as well as being able to switch off at night and sleep as without this I would only have 2-5 hours sleep A WEEK (this has been since I was very young)!"

9 / 10
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8 Report
  • tarni
  • Taken for 6 months to 1 year
  • June 27, 2019

"While Seroquel did somewhat help me, for borderline personality disorder I feel it did not help enough and the side effects for me were horrible, so I had to go off it as I could not handle it anymore. I would increase it but then the weight gain I experienced from it got worse and I was even more tired than it already made me. I would fall asleep at work and if I took the higher dosage at night, I would not wake up at all and could sleep for 24 hours straight. Decided it wasn't worth it."

5 / 10
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Are you taking this medicine?

  • It...
  • Taken for 1 to 2 years
  • November 20, 2017

"This has definitely helped with my impulsiveness and mood dysregulation. My life used to be uttermost chaos. In and out of hospitals, constantly in ER's for suicide attempts and self harm needing stitches.... This got me to the point where I can think clearly enough to actually start making changes in my life and deal with my emotions and behaviours."

7 / 10
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10 Report
  • Dizzy...
  • Taken for 10 years or more
  • July 22, 2019

"So I commented last week and its day 16 back on quetiapine 600mg The drowsiness is subsiding. I'm no longer crying about the fact I'm 36 and have no kids no friends no family and being agrophobic. I feel a lot better and I realise these drugs do help symptoms of BPD . 10 years I've been on quetiapine but I stopped 4 months ago and I was a wreck and I had to try them again and now I know they're vital . Quetiapine have given me a stomach ulcer and the pain began soon as I started quetiapine 10 years ago but its took me 10 years to realise . Be careful if anyone gets pain in their stomach you must stop smoking drinking and aspirin should all be avoided like the plague."

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  • Anonymous
  • Taken for 1 to 2 years
  • October 25, 2021

"I have been prescribed Seroquel previously to deal with post-breakup Borderline Personality Disorder (BPD) breakdown. It helped, but once I recovered I couldn't deal with the sleepiness side effect and I stayed on an SSRI for a couple of years. Recently I got diagnosed with possible ADHD as well and boy am I glad I told my doctor to try Seroquel again. I was started on Brintellix for general depression/focus and Seroquel for BPD symptom management and finally I feel like an actual person and not just a shell of myself. I used to have a tendency to hurt others verbally, be angry, break stuff, break down afterwards crying. Seroquel helps, but I had to accept the fact that it would make me sleepy at first. I slept off the initial stage of "I can't get wake up" and take it strictly in the evening at least 10-12 hours before I have to get up. A coffee wakes me up after about an hour without issues now. I am very happy with Seroquel :)"

9 / 10
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  • Pauld...
  • Taken for 5 to 10 years
  • September 23, 2016

"Been on it for 5 year started on 50mg now on 300mg as duloxetine 60mg and even tho its helped with swinges in still feel it all trapped behind a locked door and i know its the medication holding it back and every time it breaks through i end up on higher and higher doses"

8 / 10
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  • tinkz
  • Taken for 1 to 6 months
  • April 21, 2013

"I have been taking quetiapine for 4 and a half months now after suffering with Borderline Personality Disorder for years. I was first diagnosed in 04 when I was 19, 8 years later I received the same diagnosis then 6 months later started receiving treatment when I started the medicine (100mg at night). It made me sleep all night long but did not do very much for my mood, was still in a very dark place. After a couple of months I found it was not "knocking me out" the way it had been and I was starting to be up throughout the night and now I don't sleep for more then an hour before waking up at night. My mood has lifted it has only improved on a normal day but still find certain situations difficult like dealing with people outside. Hopefully it will improve."

8 / 10
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  • E90
  • Taken for 10 years or more
  • July 11, 2023

"I was on this drug for 12 years for BPD, and it worked well in the sense that my mood swings were more under control. I held down jobs, and it helped with anxiety and sleep. However, I had a blood test, and it was found that my white blood cells were low, so I was immediately taken off it. Since then, I've had to quit my job, not able to sleep, panic attacks, etc. Whether it's withdrawals or not, I don't know, but be careful when doctors prescribe you things. You should know the risks/side effects and that you could be taken off in the future."

7 / 10
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  • Tryin...
  • Taken for less than 1 month
  • August 11, 2019

"I just started this med a week and a half ago and I'm already gaining a ton of weight. I am on 50 mg. It also makes me extremely exhausted even though I take it at night. Changing it immediately when I meet with my psychiatrist"

4 / 10
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7 Report
  • mwo
  • Taken for 6 months to 1 year
  • October 31, 2022

"I am taking Seroquel XR 200mg for bipolar, Borderline Personality Disorder (BPD) and anxiety. I take it 11 hours before I have to wake up so it doesn't cause me to sleep in. It has completely prevented my social anxiety, helped me to make new friends, prevented my panic attacks and depressive episodes and I'm sleeping so deeply now my night terrors have stopped as well. The downside, however, is I am rarely as happy as I used to be. During my highs I felt on top of the world and now I find it hard to romanticize any moment of my life. Nothing feels special or extraordinary. It's a bit boring. Even music doesn't feel the same."

6 / 10
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  • Emily...
  • Taken for less than 1 month
  • May 5, 2012

"I have been taking Seroquel for two nights now, 50mg. It makes me extremely drowsy, right now I feel very out of it. But for the first time I'm socializing. I'm calm and have had less psychosis. Have hallucinated today but it hasn't been frightening. I'm just happy I'm socializing again! Just the drowsiness can be a bit of an issue. I've also felt sick on them but it's only been two days."

3 / 10
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  • Hanna...
  • April 3, 2017

"Was on 25mg quetiapine fumarate for years and was recently bumped up to 50mg. This is probably the best medication I have tried (and I've tried quite a lot). It's the only thing that will let me sleep and has only given me very few, if any, side effects. (I am very groggy if I get up in the middle of the night and it increases my appetite (but only for a few hours after I take it)) thankfully I have not gained weight due to this medication and I hope it stays this way."

6 / 10
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9 Report
  • charl...
  • Taken for 1 to 2 years
  • January 28, 2018

"27 y/o male here. I have a diagnosis of Borderline PD and Bipolar Affective, and I use quetiapine for both. I'm on 150mg, of which 100mg is XL and 50mg is IR for sleep. This drug is extremely effective in treating mood disturbance, acute depressive episodes and general anxiety or exacerbations of BPD. I increase my dose every time I trigger acutely and it calms me down. Drawback are I get hypotension from the XL, meaning I feel feint, dizzy and nauseas multiple times a day. Last but not least, I gained 40lbs whilst on it. Were it not for the weight and the hypotension it'd be the perfect med- insanely effective and highly recommended."

7 / 10
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8 Report
  • Princ...
  • Taken for 1 to 6 months
  • October 22, 2019

"I currently take 50mg of quetiapine before bed. I must say it gives you the most brilliant night sleep. So for anxiety it will help your sleep to be reconciled! These meds are good at keeping me calm during the day. I’ve stopped crying daily at least ! Sadly they haven’t found my smile again and I find my skin is incredibly greasy from the increase in serum and my skin is very spotty. ."

4 / 10
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6 Report
  • Crod
  • Taken for 1 to 6 months
  • May 14, 2021

"This medication has changed my life and restored peace to my mind! I take it alongside adderall XR and prosozin. It seems to be the best med combo I've been on. My anxiety has been cut down significantly, this medication works better than benzodiazipenes which I do not want to take. My impulsiveness has been cut down significantly, I sleep better, act better, feel better, function better all of it. No weight gain for me, as I watch what I eat. only thing is be ready for some CRAZY DREAMS, and I mean crazy. Life changing med yall."

10 / 10
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4 Report
  • Anonymous
  • January 5, 2011

Seroquel (quetiapine) "I'm on 700mg of Seroquel. The worst side effects I have are intense hunger and weight gain and a decrease in my sex drive. Both of these are horrible, but my mind is clear. Not sure if it's worth it or not. Wondering if there is a medicine out there to add to my regime that will deplete my hunger and boost my sex drive."

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  • Lulu
  • Taken for 1 to 6 months
  • October 23, 2022

"I'm 37 and only just diagnosed with Borderline Personality Disorder BPD, I have struggled with it since I was 16, on and off many different antidepressants with no effect. I'm on 50mg of quetiapine now, had a few minor side effects the first week, night sweats, fatigue, palpitations. I'm so glad I gave it a chance, it has been a life saver for me. Not disassociating as much and my mood has lifted. I've been able to join a gym and keep at it, my manic episodes have stopped. No weight gain, it has actually suppressed my appetite a little. My advice would be, give it a go if you need it, the side effects generally disappear after a few days just stick with it."

10 / 10
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  • Kimmie
  • Taken for 1 to 6 months
  • August 20, 2017

"I take 300 mg daily, 200mg of that being at night, and it actually keeps me awake and gives me restless legs. Side note I also take 150mg Zoloft in the am. Both for BPD and bipolar. Maybe my moods are.a bit more stable but compulsions seem the same."

5 / 10
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  • Seroq...
  • Taken for 1 to 6 months
  • September 7, 2023

"I have been on countless meds for most of my life, and nothing has ever really worked. About a year after I got diagnosed with BPD, I suffered the loss of a parent, and everything was spiraling. My psychiatrist put me on quetiapine (Seroquel), and it has changed my life more than I thought any med could over the past few months. I truly feel like I’m in control of my emotions for the first time in years and years. I am so much less paranoid, and it helps with my social anxiety a lot. I am taking quetiapine (Seroquel) and trazodone at night, and that is the least amount of meds I have ever taken, and I’ve never done better. I highly recommend quetiapine (Seroquel) if you have BPD and are offered a prescription. I have tried so many meds, ketamine treatment, everything. Nothing has helped me like quetiapine (Seroquel). I have had to up my dose, and I hope my body doesn’t build up a tolerance too much because it really helps me stay calm and collected."

9 / 10
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  • William
  • March 12, 2018

"I was originally prescribed quetiapine 25mg for sleep as an add-on to my other meds when I was in hospital. My understanding is that under about 100mg it has no effect other than as an alpha-histamine blocker, which is essentially the same as benadryl. For antipsychotic effect, a larger dose is needed, and for sleep, the side effects seem to outweigh the benefit vs., for example, benadryl itself. Having said that, since there has been some benefit shown at higher doses for BDP, someone with this condition likely has nothing to lose to take it at 25 or 50mg. Others have mentioned that it aggravates their restless legs syndrome, and it does the same for me - but 300mg of gabapentin easily takes care of that, and 300 or 600 works great for RLS regardless. The other issue I have with quetiapine is heartburn but for that I have an Rx for generic Zantac which works like a charm. I can't speak to the benefits of "therapeutic level" doses of quetiapine as I have never been on more than 50mg."

5 / 10
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  • Alfi
  • May 13, 2021

"I have bipolar type 2 and borderline personality disorder and ADHD as well. I tried risperdal, had hormonal problem, try abilify: I had lots of dyskynesia and tics. I was also on Vyvanse for ADHD, which is like speed( but cleaner) and Concerta. But the best combo I had and I'm still on it is Quetiapine XR 400mg every evening and wellbutrin 150xr every morning"

9 / 10
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  • angst
  • March 26, 2011

Seroquel (quetiapine) "I have been using Seroquel for about 18 months together with Pristiq. At first I took 25g at night then I added to that 100mg Seroquel XR. I seemed far more relaxed and able to cope with life a little better. However over the last 2 months the agitation became unbearable and my depression increased immensely. I have dropped 50mg of the XR over the past few days and I am already feeling less anxious and agitated."

6 / 10
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9 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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