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Quetiapine for Borderline Personality Disorder User Reviews (Page 2)

Brand names: Seroquel, Seroquel XR

Quetiapine has an average rating of 7.6 out of 10 from a total of 127 reviews for the off-label treatment of Borderline Personality Disorder. 66% of reviewers reported a positive experience, while 9% reported a negative experience.

Reviews for Quetiapine

  • finally
  • Taken for 1 to 6 months
  • August 2, 2013

"I was first diagnosed with Borderline Personality Disorder eight years ago in my teens. Co-morbid major depressive disorder, post traumatic stress disorder, panic disorder. I have only been on this medicine for just over two months but it has changed my life. It is available generically and affordable. I also suffered from insomnia from a very young age and now about 30-45 min after taking my pill I dozed off for exactly 8 hours of sleep and wake up rested and refreshed. If I have to be up for something in the morning I need to remember to take it ~9 hours before I need to get up. It's a minor inconvenience compared to all the good it has done me. I am a much calmer person."

9 / 10
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  • Crazy...
  • Taken for 1 to 6 months
  • April 8, 2014

"I have been on Seroquel for about 2 months because I suffer from BPD, Bipolar disorder and depression. As I am still building up to find the right dose for me (currently at 200mg), but I have to say that the positives of this medicine are so much more than the negatives. I used to break out in anger fits to the point where I couldn't stop the anger and had to be held down. I would break into a crying fit seconds after being in a happy mood. Starting the Seroquel, within a week, my depression seemed to lower, my extreme paranoia disappeared, my anger subsided. I have discovered (after reading another review on here) that after alcohol drinking I get crying fits and anxiety attacks for a few days. I am excited to feel "normal" for once."

9 / 10
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  • Anony...
  • November 11, 2010

Seroquel (quetiapine) "I am 4 weeks in to taking 25mg of Seroquel and I noticed the difference almost straight away. I can think so much better because my anxiety is reduced enough for me to think in straight lines again. I am no where near as paranoid and a bit less dissociative too which is all really good. I was also prescribed Cymbalta for depression but have just ditched that because I was too fearless and suicidal on it. Whilst Seroquel is not touching my depression, I noticed that after taking it I felt that I gained a degree of self-control back which helped me to start to use basic life skills that I have learnt, which help me to deal with some of the BPD approaches to life's problems. Seriously, I find Seroquel even at the low dose to be excellent."

9 / 10
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46 Report

Frequently asked questions

  • chell...
  • October 5, 2008

Seroquel (quetiapine) "I am 12 months into taking Seroquel for BPD and I feel more settled happy and relaxed without the insane anger outbursts and days of crying I experienced with some other medications. It may not be for everybody, but for some of us, it does work and gives us our quality of life back."

8 / 10
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50 Report
  • Cheesy...
  • Taken for 1 to 6 months
  • February 11, 2019

"I have struggled from and very young age of depression and anxiety very badly. I have tried so many different medications and this is by far the best!! I don’t think I could have carried on with life without this medication, I had really bad insomnia as well now I get a great nights sleep. I suffer from border line personality disorder, very bad depression, anxiety, insomnia and autism spectrum disorder. To anyone who’s thinking of taking this medication I would definitely recommend it."

8 / 10
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22 Report

Are you taking this medicine?

  • Meegz
  • Taken for less than 1 month
  • January 7, 2015

"I stayed in my own little comfortable world as I called it because I was paranoid, bad compulsions, habits, hypochondria, everyday was a struggle and I would cry randomly. I did not consider myself depressed because I was such a happy girl even though at a split second I would turn into something else and would have no emotion for anything. Sometimes I would have bad anxiety due to giving myself all of this stress and I couldn't eat and then I became sick and most of the time with that, came no confidence and sometimes I had many flowing ideas and such creativity. I was diagnosed recently with Hypomania, BPD and a bit of skitz. This med has helped so much but if you have symptoms of bipolar do not take anxiety medication...you'll feel terrible."

8 / 10
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34 Report
  • Limo
  • Taken for 5 to 10 years
  • December 24, 2020

"I've been using quetiapine for 5 years and my psychiatrist has told me from the very start I may be on it for many years too come or the rest of my life. I've only just overcome that fact really, From the start I felt extremely “High” or “Sedated” (I was prescribed quetiapine for hallucinations and night terrors, I started on 75mg and I'm currently on 250mg and over the years despite the start up side effects from 2-4 weeks maybe 6 weeks for some people, it is still a brilliant drug for my BPD and PTSD. I still get low points but I bounce back fairly quickly and I feel quetiapine has stabilised my mood throughout the years of taking it."

8 / 10
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  • Tina...
  • December 18, 2015

"I have been on Seroquel (75 mg, with 75 mg of Zoloft) for 2 months now. It's the only thing thats completely managed mood swings (along with weekly DBT therapy). I have PTSD, anxiety, depression, and an eating disorder. I'm on Seroquel for mood swings. It's helped me sleep through the night and feeling refeshed in the morning. Weight gain was not a problem for me, but the headaches when I first started taking it (within the first week) were excruciatingly painful."

9 / 10
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30 Report
  • Charl...
  • Taken for 6 months to 1 year
  • October 6, 2016

"I really have a love/ hate relationship with Quetiapine. Here goes... Love- keeps moods stable, helps with my psychosis and disassociation linked to Bipolar and EUPD. I feel like it keeps my more volatile mood swings back and helps me to be calm in situations I would ordinarily struggle with. Hate- Man, it makes me eat. I've been on it for 9 months and I've put on just over 2 stone. I hate being this heavy but it seems no amount of gym sessions (I'm extremely physically fit but can't loose the weight) and diets help. Every night I go the fridge after I've taken 200mg of it. It also makes me super tired and I REALLY struggle to get up in the morning. I also feel like I'm trapped in a cycle- if I come off it, my moods are awful."

6 / 10
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  • Noone
  • Taken for 1 to 2 years
  • May 9, 2020

"quetiapine helped me a ton in terms of emotional instability and sleep. I was on 150mg for about a year. All going fantastic. Then 100mg because of unrelated heart problems now 50mg because of swallowing problems that have lasted the entire time. Since being on the 50 I am unable to sleep and have suicidal and self harm thoughts everyday unable to work. I wish I didnt' have swallowing problems as this med changed my life. I have had no weight gain either."

8 / 10
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  • deede...
  • Taken for 1 to 6 months
  • August 12, 2019

"I decided to stop taking it because of the massive weight gain BUT at 100mg, it did help my Borderline Personality Disorder - you end up feeling NOTHING rather than everything, I guess it depends on the person. I lost my actual personality but gained a more normal reaction type and my mood was generally 'better' - I was more neutral rather than the extreme highs and lows I also had a few side effects; extreme drowsiness, weight gain (I'd say approx. 2st in 2 months), a complete lack of motivation and also *weirdly* awful restless legs for about 2 hours after taking it."

5 / 10
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19 Report
  • MissL...
  • Taken for less than 1 month
  • April 2, 2018

"I was recently diagnosed with BPD after years of suffering with emotional problems on top of depression and anxiety. Antidepressants don't seem to touch the BPD and I worked with my psychiatrist to get on Seroquel (regular not extended release). I started at 25mg and then titrated up to 50mg as prescribed. At first, it caused drowsiness but that wore off after a few days. My family and I have definitely noticed my emotions are much more levelled and I don't feel anxious nearly as much as before. It helps with the quality of sleep but I still struggle with insomnia as far as when I go to bed (not currently working). I'm very happy with the results so far."

8 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • July 23, 2013

"I have been taking Seroquel XR consistently for almost a year. I recently decided to try to lower my dose from 200mg/night to 100mg/night because I'm fed up with the weight gain (diet/exercise don't seem to do much to combat it), but I began to feel unstable a few days after lowering the dose. On Seroquel XR I am content, even-tempered, not very anxious, no paranoia, no self-harm thoughts, but when I mess with the dosage or stop it entirely I quickly remember why I take it. I instantly begin to assume that others don't care about me, to feel lonely, impulsive, and very down for no reason. I'm hoping to switch to a medication with a similar mechanism as Seroquel XR without the weight gain...(Geodon...?)"

8 / 10
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  • Timy
  • Taken for 6 months to 1 year
  • April 29, 2020

"I’m currently on 50 mg of Seroquel. It has helped a lot with psychotic symptoms related to BPD (borderline personality disorder), I haven’t had auditory hallucinations on it at this dose. It’s also helped boost my appetite which I was struggling with. The drowsiness made morning classes difficult since I was put on it while attending college, but overall I’d say the side effects are preferable to the symptoms the Seroquel is treating. It also seems to help taper down my impulsiveness."

7 / 10
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15 Report
  • Average...
  • June 21, 2016

"I'm at the two-week point. And while it's still a bit painful to get out of bed, once I do I no longer feel "stoned." There is a light at the end of the tunnel. Days one through five were as follows: 50 mg, 100 mg, 200 mg, 300 mg, 400 mg. Then it was a matter of getting my body acclimated to 400 mg, which I thought would never happen. If you are able to take vacation/sick days/medical leave, I do suggest it. I did not. Either way, just know it does get better within a matter of weeks."

8 / 10
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25 Report
  • yorki...
  • January 28, 2009

Seroquel (quetiapine) "I've now been on this drug for 5 months. I haven't self harmed during this time. I have gained some weight, although in recent weeks I've been able to stop bingeing for the first time in years. I tend to wake up feeling down or agitated, so perhaps the pills aren't working for the full 24 hours. However, once I've taken the medicines I am calm again. The major downside is that I easily sleep for 14 hours straight and find it impossible to motivate myself to do anything. The days go by very quickly and I do little other then eat, sleep and watch TV. In the long term this has to be a bad thing, but for now I'm happy not to be feeling ill."

7 / 10
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41 Report
  • Bpd...
  • Taken for less than 1 month
  • May 9, 2016

"I began taking Seroquel 100mg 3 nights ago, it has helped alot. I have been suffering for 20+ years and didn't know I was bpd. At first I was diagnosed E.H. (emotionally handicap) when I was 12, then when I was 30 Dr. Said I had Alcohol induced Psychosis. Now Im 38 and I have BPD. The emotional roller coaster in my brain sucks. I go from Suicidal thoughts to smiling and shaking hands and Pleasant conversation. Mostly Im depressed, I have paranoid thoughts as well. Seroquel has calm that down alot. I slept great the first night then woke up 4x next night last night about 4x as well. I don't feel any emotion. Everything is slow and I have stop talkinh to myself , with a few words here and there. I hope I get better."

9 / 10
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25 Report
  • Estab...
  • Taken for 6 months to 1 year
  • June 15, 2019

"I take quetiapine 250mg each night alongside 200mg sertraline nightly and 200mg lamotrigine through the day for BPD and it's balanced me perfectly. It is the best drug combination for BPD and an absolute lifesaver. Literally does all the heavy lifting."

10 / 10
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  • Gano
  • Taken for 6 months to 1 year
  • September 26, 2019

"Used quetiapine as a mood stabiliser when first dx with Borderline personality disorder and dysthymia, no change in mood, or reactions and gained 10kg. Tried recently for sleep, 25mg no difference, 50mg no difference"

1 / 10
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16 Report
  • Truc
  • June 16, 2018

"I was diagnosed with Bi Polar 9 years ago and have been taking 100 mg every night for the 9 years and it has been very positive and life changing. Before being diagnosed I had been drinking at least 4 nights a week. I would stay out those nights until there was no more alcohol to be found ! The booze almost cost me my marriage and family. From the first night of taking the medication I quit drinking and maybe have had 6 beer in 8 years. It has helped me to sleep and have had no side effects. It’s a life saver a family saver and I believe it has saved my life. I now depend on it. There have been times when I have run out, I can not sleep at all not a wink. Again it has changed my life very positively. Wish the diagnosis would have been at a young age . I am 60 years old now and the last 9 years have been better"

10 / 10
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  • Broken...
  • Taken for 1 to 6 months
  • July 3, 2013

"I started on quetiapine nearly 5 months ago after switching from chlorpromazine for the mood stabilizing properties. I'm on 600mg of the XR version nightly. It took a nearly 2 months for me to notice an effect but once it did take effect there was a great difference. I went from being incredibly low with repeated drinking, self harm & hospital admissions to a deep stability I haven't experienced in years. I've not self harmed now for 3 months & also quit drinking alcohol. My mood is on very much an even keel with no extreme highs & lows. I'm just happy at a normal level & enjoying life & am dealing with things so much better. Only negative is slight weight gain but it's a price I'm willing to pay for this stability."

10 / 10
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29 Report
  • A Sav...
  • Taken for 1 to 6 months
  • April 13, 2016

"My psychiatrist and I decided to give this a try when my Effexor was helping my depression but not my anxiety. I was also having constant episodes of insomnia and felt angry all the time. 50 mg wasn't enough, so we upped it to 150 mg, where I felt great--my anxiety was eradicated and I was able to sleep fine, but I was still having an issue with anger. We went up to 300 mg as a last ditch effort to help the anger and all that did was make me really groggy and out of it all the time, which actually made my anxiety worse. So we went back down to 150 mg, and that's where I am. All in all I really like my Seroquel, but I feel like it made me gain weight a bit easier--not a large amount but between 5-10 pounds, but my diet also isn't great."

8 / 10
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23 Report
  • MRSCO...
  • August 19, 2012

"I am 32 years old, I got diagnosed with Borderline Personality Disorder a mere 6 months ago but I have definitely been suffering with BDP since I was 11. Since taking quetiapine I am no longer an insomniac (the longest I went without sleep was 4 days). I have no racing thoughts, no more paranoia; my rages are less I can deal with people in a more diplomatic way than before. I am far less irritable or argumentative the only downside is slight weight gain, but I try to be very mindful about food because I have high cholesterol and heart disease runs in my family so I have to be careful. I also get slight tingling in my fingers. I am on 100mg at night and 50mg during day; it takes the edge off at work because I have a very stressful job!"

9 / 10
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30 Report
  • Smith
  • Taken for 1 to 2 years
  • January 25, 2019

"I have BPD I take 90mg of Duloxetine in morning and 300mg of Quetiapine at night. It works very well for me. I find it hard to loose weight but I would rather carry a bit of weight and be mentally strong."

10 / 10
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16 Report
  • Omnia
  • Taken for less than 1 month
  • May 15, 2019

"Quetiapine was given to me for BPD and it worsens my mood. I'm in a depressed phase since I started it! It also makes me feel so angry and easily irritated. I can't function properly up to 4 hours after I wake up. It causes muscle pain and it affects my training but this side effect is dose dependant. I hate this drug"

5 / 10
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15 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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