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Prucalopride and Upset Stomach: What Users Say

Brand names: Motegrity

Upset stomach: mentioned by 6 users (5.8%)

Based on user experiences from 103 Prucalopride reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

headaches 32.0%
nausea 15.5%
diarrhea 13.6%
depression 12.6%
gas 9.7%
anxiety 6.8%
bloating 6.8%
vomiting 6.8%
abdominal pain 5.8%
upset stomach 5.8%

Reviews for Prucalopride

Commonly mentioned side effects
  • Deb...
  • September 7, 2020

Prucalopride for Chronic Idiopathic Constipation "One Motegrity pill, and had side effect of a horrible headache, and it made my stomach so upset, and one day out still feeling like I'm going to throw up and bloating. Never again. I will no longer be ever taking this pill. I'm so sick from just this one pill."

1 / 10
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50 Report
  • Anonymous
  • Taken for less than 1 month
  • October 15, 2021

Prucalopride for Chronic Idiopathic Constipation "I had a free trial (7 pills) from my GI doctor. I'd never afford this because it's $300 without insurance a month. I took a quarter of a pill for several days of constipation and stomach burning. Within 30 min, I had diarrhea with solids. I haven't had loose stools in over a year, and I was actually pleased not to give birth for once. I didn't have worse cramps than I was already having, and I didn't get a headache like others warned. I only weigh 120 lb, and I saw others say they had better success with smaller doses. I can say this medicine works way better than OTC stool softeners I've used if you need an immediate BM."

8 / 10
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17 Report
  • Kar...
  • Taken for less than 1 month
  • February 1, 2022

Prucalopride for Chronic Idiopathic Constipation "I’m looking for personal experiences… Does taking this medication, day 1 hour before the first meal of the day, work better than taking Motegrity with food? I’ve been taking it on an empty stomach in the AM. The good response for me is no belly ache all night long."

7 / 10
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15 Report

Frequently asked questions

  • Wee...
  • Taken for less than 1 month
  • November 20, 2020

For Chronic Idiopathic Constipation "I just started to eat prucalopride because of chronic constipation. I eat this medication with the stomach medication (Dexilant). Now I feel very stomach upset. I have diarrhea after half an hour of eating the medication. Feel a little headache. I don’t know if it’s that side effect of this medication or the stomach medication."

3 / 10
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0 Report
  • Anonymous
  • Taken for less than 1 month
  • February 26, 2022

Prucalopride for Chronic Idiopathic Constipation "I have taken it 3 times, and each time the same side effects, all within 15 minutes of taking the medication. Bloating was the worst, along with stomach ache, nausea, and severe headache!! No thanks."

1 / 10
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15 Report
  • Ric...
  • Taken for less than 1 month
  • August 10, 2019

For Chronic Idiopathic Constipation "I tried 2 mg prucalopride, and it worked the next day, however, terrible stomach pains and gas lasted and I still have gas and an upset stomach going on to day 3 since using it only once."

2 / 10
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9 Report

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