Prochlorperazine User Reviews & Ratings (Page 4)

• ano...
• November 29, 2018

Prochlorperazine for Nausea/Vomiting "My mother had a colonoscopy and had a vocal chord spasm, which caused her to cough during it. They gave her some medicine (I don't remember the name) to help dry up her secretions and calm down the coughing. This made her chest tight, painful, and made her feel nauseous after she got home. I took her to the ER, she is allergic to Reglan, so they gave her a mix of Benadryl and Compazine for nausea. Within 5 minutes, she was jittering around and felt like she wanted to rip her IVs out and run home. Her anxiety skyrocketed and her heart rate went up to 154 bpm. It wasn't until they gave her Ativan that her heart rate went down and she was able to calm down. We got sent home, and she was still anxious and fidgeting around for about 4 hours until she finally fell asleep. She woke up and still felt a little anxious and fidgety, but not near as bad as last night. One of the worst experiences she and I have ever had, and she is going to have it noted that she is allergic so she never has to go through it again."

• mmm...
• July 11, 2016

Prochlorperazine for Nausea/Vomiting "If I could rate this lower than a 1, I would. Worst. Experience. Of my life. I had severe nausea from a dental infection in the hospital, and the doctors gave me Compazine through IV. I don't even know when this happened, but I had a crazy out-of-body experience. I saw myself laying in my bed and had no idea where I was. I thought I was in Arizona at first, at a hotel, and then freaked out because I had no clue who the people in the room were (my parents, my regular nurses). The room spun, and then I vomited everywhere. It was horrifying. I was nauseous for about twelve more hours and then had hallucinations. I saw people walking in and out of my hospital room that I knew damn well weren't real or there. DO NOT TAKE THIS DRUG."

• Mar...
• Taken for 5 to 10 years
• July 12, 2014

Prochlorperazine for Nausea/Vomiting "Been taking for years for nausea from Irritable Bowel Syndrome, etc. Works great and quickly! Get restless legs next day, but that ends quickly. Heard that if taking it regularly long-term, you should have liver and kidneys monitored, as it can do damage to them!"

• Bir...
• Taken for less than 1 month
• August 23, 2020

Prochlorperazine for Nausea/Vomiting "Went to the ER with extreme dizziness. They wound up giving me Compazine. I wasn’t even familiar with what it was. I felt strange at first, but then my hands contorted and froze. My mouth had almost completely clamped shut. An orderly or a CNA just happened to come by to empty trash. I barely was able to say, 'Please go get someone, something’s not right.' The doctor at first thought I had stroked. He ran some tests, gave me some Benadryl, which helped. I would never take this drug again."

• EAa...
• Taken for less than 1 month
• August 16, 2019

Prochlorperazine for Nausea/Vomiting "I've never experienced anxiety, I don't take any medication for anxiety, but thanks to this drug, I had my first panic attack. I went to the ER for extreme nausea due to painkillers given to me to alleviate the pain of some kidney stones. Right after being given this medication, I started feeling jittery and like I couldn't breathe. Ten minutes later, I wanted to rip out my own IV, my entire body was shaking and was having facial contractions. The doctor laughed it off, saying I was being overly dramatic and I just needed to breathe. It was the worst experience I've ever had, and I thought the kidney stones were bad enough. Three days later, and I'm finally starting to feel like myself again. I will never take this drug again and have no idea why it's still on the market."

• Mad...
• February 10, 2018

Prochlorperazine for Nausea/Vomiting "I went to the ER with a migraine, and I got this through an IV. I was totally fine and all happy until this drug hit me. I went completely insane. I got claustrophobic, I wanted to kill myself, I started twitching, and I got super anxious. They gave me some Benadryl, which helped, so they sent me home. On the way home, it happened again, and it kept happening all night, even after I kept taking Benadryl. The only time I felt not insane was when I was sleeping, but I was still having weird dreams. The next morning, I woke up, and I was still really anxious, but the serious side effects went away. For 2 more days, I still felt anxious, and it was the worst thing ever. Everyone told me this was really rare, and I don't think any of the people there at the ER really knew what was going on. This is a scary drug. I just wanted to share my story."

• Nan...
• August 2, 2016

Prochlorperazine for Nausea/Vomiting "I was taking Zofran for years for severe nausea. During a hospital stay, I was given Reglan and had horrible hallucinations, and my skin was crawling, like some people in the reviews had with Prochlorperazine. However, Zofran stopped working for me during the last bout of nausea, so my doc gave me Prochlorperazine, which helped tremendously, and thankfully, I had no side effects."

• Rut...
• Taken for less than 1 month
• November 29, 2018

Prochlorperazine "I went to the ER for a migraine and was given this medication combined with Benadryl. It basically induced a panic attack, and I felt as if I couldn't breathe properly. It was awful, especially as I wasn't anxious about being in the ER, but after taking Compazine, I just wanted to leave."

• Sha...
• November 6, 2019

Prochlorperazine for Nausea/Vomiting "This was, like many others on here have said, a terrifying ER experience. I was given Compazine for what they thought was a migraine, plus Benadryl because they warned me about the anxiety. Upon giving it to me via IV, I felt a wave of panic enter my body. My heart stopped for a moment. I immediately wanted to get out of the hospital and tried to rip my IV out. I thought that would be the end of it. But it wasn't. I had crippling anxiety over the next 5 days! Yes, FIVE days. I had constant panic attacks where I would have to stop driving and pull over. One time I almost fainted during a meeting and had to go to the clinic. This drug made me dizzy, lightheaded, feeling like I was going to pass out all the time, gave me the strangest head pressure/tingling feeling, heart racing constantly. I will never ever take this drug again. Worst experience."

• Nau...
• August 18, 2014

Prochlorperazine for Nausea/Vomiting "Read the side effects carefully. I had a severe dystonic reaction and had to spend the day in the emergency room after just 1 pill. I have been advised by my doctor to never even take anything in this family of medicines."

• Son...
• November 18, 2008

Prochlorperazine for Nausea/Vomiting "I used it after a surgery when the anti-nausea patch wasn't working well enough. I took off the patch, used the suppository, and had no more nausea. Used it again after several hours of vomiting and diarrhea due to assumed food poisoning. It was BAD (vomiting every 20 minutes). Then I remembered I had a leftover suppository. Used it and didn't throw up once afterwards. I was able to go to sleep and woke up hours later when my fever had passed."

• Usl...
• April 6, 2019

Prochlorperazine for Nausea/Vomiting "I was given a migraine cocktail that had Compazine included in it. This medication made my symptoms a million times worse! I started with my heart pounding and a severe anxious feeling immediately. I was given this med through an IV. It literally felt like an instant panic attack. It's been 4 days now, and I still am having spontaneous bouts of anxiety due to this medication. The half-life is 24 hours with this med, and it's been well over 96 hours since I was administered it, and I'm still experiencing side effects. I also got low blood pressure, which gave me cold sweats, disorientation, and I was freezing. My only relief was from hot baths, which made my blood pressure go up some. I also had dissociation, as if I wasn't even myself, from this medication. I cannot stress enough how awful this medication is, and it should NOT be used as nausea relief unless it's for EXTREME circumstances. This medication is used in people with schizophrenia! I am still not myself days after, and it's miserable."

• Dam...
• January 2, 2019

Prochlorperazine for Nausea/Vomiting "Went to the ER for a severe migraine... They gave me Compazine and Benadryl. 20 min later I was in a severe panic... ripping my IVs out. Calling out to the nurse, saying I was leaving!! They had to give me more Benadryl to reverse it. I left the hospital feeling worse than I did when I went in!! Horrible experience!"

• NE6...
• Taken for less than 1 month
• February 1, 2019

Prochlorperazine for Nausea/Vomiting "I had experienced high agitation and restlessness with this drug before, so it’s been on my allergy list. Unfortunately, I was going through a difficult procedure, and it’s the only anti-emetic this office offered. It had been over 10 years since I took it, so I figured I’d try it again. Bad idea. This drug causes severe anxiety, agitation, muscle pain, and a general feeling of needing to rip out of your skin! I remember now why it was on my DO NOT USE list, the effects stay with you for a long time too. I will never take this again. There’s a reason it’s listed as a mental health drug/antipsychotic. In my opinion, it MAKES you psychotic."

• Me2...
• January 22, 2021

Prochlorperazine for Nausea/Vomiting "I went to the doctor because of my dizziness and nausea. The doctor had prescribed Compazine to me for my nausea, which didn’t even work. Jump forward a few days, and I go to the ER to see if they can do something about it when I noticed I started having seizure-like attacks, where my body would stay in one position and my eyes would roll to the back of my head. The doctor said it was because I was allergic to the drug, even though I didn’t know. But isn’t Compazine supposed to no longer be sold?"

• Mee...
• March 30, 2014

Prochlorperazine for Nausea/Vomiting "I have been dealing with chronic nausea/vomiting for almost a year. I have had every test in the book, and they all come back negative. I've tried medications for irritable bowel syndrome, and I've tried Phenergan and Zofran, none of which worked. I also used the transdermal Scopolamine patch, which helped a little. Finally, my doctor prescribed Compazine suppository, and I have had great relief of my nausea/vomiting. I hope to be able to stay on this for a long time. It is a wonder medicine."

• Bab...
• Taken for less than 1 month
• October 22, 2018

Prochlorperazine for Nausea/Vomiting "I'm just getting this medicine for a headache cocktail. And let me tell you, I wanted to jump out of my own skin. I have never felt anything like it, it was absolutely horrible. Do not let them give you this medicine, especially if you have anxiety, which I have, and they knew that because I told them. Absolutely horrible, like your legs have bugs all in them, and they're just crawling everywhere. Never, ever again!!!!"

• Smo...
• Taken for less than 1 month
• July 4, 2021

Prochlorperazine for Nausea/Vomiting "I was given Compazine along with Tramadol via IV at the ER to help treat a bad migraine. As soon as they put it in my IV, I wanted to rip it out and leave. My mom was with me, and I stayed a few more hours until my bloodwork came back. I finally got discharged and just wanted to go home and sleep, but of course I couldn’t. I was jittery and shaky. I was pacing back and forth in my room. I couldn’t sit still. I can’t find the words to describe exactly what I felt, but I basically felt so uncomfortable and like I was going insane at the same time. I went back, and they gave me Benadryl, which did absolutely nothing. Luckily my mom had some leftover Lorazepam, which finally gave me some relief and allowed me to sleep. It took 2 days for the worst of it to wear off, but now, 6 days later, I still don’t feel 100% back to normal yet. I will never take this medication ever again, and I hope it gets taken off the market soon. I hope no one else ever has to experience what I did."

• Dra...
• Taken for less than 1 month
• November 5, 2022

Prochlorperazine for Nausea/Vomiting "Was given this drug in the ER for a migraine and nausea, they didn’t tell me what they were given, and I had the worst headache and didn’t even ask. Lo and behold, this medicine ruined my life after one dose!!! Was given with Benadryl, and I felt extremely anxious, panicky, my legs and body were so restless I thought I was gonna die on the CT table. I couldn’t put words together. It’s been 5 days, and I’m still not the same: panic attacks galore, anxiety, tight band around head/headache, fear of doom, and dizziness galore. This should be illegal."

• Nat...
• Taken for less than 1 month
• April 29, 2023

Prochlorperazine "I went to the ER with the worst headache of my life. After a spinal tap, the doctors determined I had encephalitis. The pain I felt from that and the spinal tap were bad enough, but even that wasn’t as bad as the pure dread that Compazine made me feel. Prior to administering it, my nurse warned me that some people can have a bad reaction to the drug, but she said Benadryl typically counteracted those negative side effects. I wish I’d had the sense to ask more questions first! Within five minutes of taking it, I felt like I needed to crawl out of my own skin. I’m a pretty calm person with a good grip on my emotions, but I felt like I lost all control in that moment. I screamed at my nurse and told her to get it out of me. Knowing now that they could’ve given me Ativan to calm me down irritates me a little because they made me lay there and suffer through it for hours. Luckily, the side effects didn’t last more than a few hours, but it felt like an eternity."

• Kat...
• Taken for 1 to 2 years
• November 8, 2022

Prochlorperazine for Psychosis "First and last time I ever received IV Compazine. Within minutes of hitting my veins, I was severely anxious, like an acute psychosis. I jumped up from the bed and said, 'I gotta get out of here, I gotta go.' My husband was like, 'What the hell did they just put in your IV?' He called the RN in, and he gave me IV Benadryl, which did not help me. For the next 3 days, I was out of my mind, could not function, and honestly was scared to be alone for fear I may have hurt myself! My husband stayed home to care for me and make sure I did not hurt myself or take off running. Oral Benadryl and oral Ativan--nothing took the feeling away. Absolutely awful! I have never in my life had feelings of hurting myself or dealt with any mental health issues, it was completely terrifying! I don't understand why this medication is still on the market honestly!"

• Ren...
• October 30, 2015

Prochlorperazine for Nausea/Vomiting "Had nausea from chemo and radiation and was given Zofran. Zofran did nothing to curb the nausea. I was just recently changed over to Compazine and the nausea is gone! I've not experienced any side effects whatsoever."

• Sil...
• Taken for less than 1 month
• December 15, 2017

Prochlorperazine for Nausea/Vomiting "I was born with chronic pancreatitis and chronic migraines, so vomiting is a for sure thing every time I visit the ER. I have never in my life been traumatized by a medication until this encounter. It is like we are their lab rats, you feel helpless, insane, delusional, 51-50, a psychopath. You literally feel trapped inside your body, if that makes any sense. I try to hold my composure off this medication because it literally makes you crazy. It should be illegal for them to inject you with it without a warning on the side effects. You feel so weird for 3 days, it’s as if your innocence has been robbed from you, a form of violation."

• Dai...
• September 15, 2017

For Anxiety "I received this medication over the counter at my local chemist for severe nausea, dizziness, and headache. It worked within 30 minutes to alleviate the nausea completely, and the headache is subsiding. I also have severe anxiety - the side effect of drowsiness has occurred but has helped calm me down a lot, so I can rest, and the dizziness is no longer noticeable, so I see that as a bonus."

• NoG...
• February 7, 2020

Prochlorperazine for Nausea/Vomiting "I was given Demerol and Compazine to combat migraine and experienced severe agitation. The doctor recognized phenothiazine-induced akathisia and countered it with Benadryl and Ativan. Years later, I was again treated for HA. I double-checked the doctor knew I couldn't take Compazine. He ordered chlorpromazine and Valium. Unfamiliar with the generic, I didn't realize it was Thorazine (in the same class as Compazine). Another bad reaction. I pulled the IV out, fled, and paced at home for 15 hours. Surely, the doctor knew I'd react negatively. A couple years later, back to the ER for the first time since the Thorazine. I explained my reactions in detail. This time I was given Reglan. Again, I ripped out the IV and was headed for the door when the nurse caught me. Repeated doses of an antidote worked. I learned, subsequently, it's common to react badly to Reglan if you reacted to Compazine. Either the doctor was poorly informed or simply willing to risk my well-being. I've suffered at home in silence ever since."