Medically reviewed on June 7, 2018
Available Dosage Forms:
Therapeutic Class: Antiemetic
Uses For This Medicine
Diphenidol is used to relieve or prevent nausea, vomiting, and dizziness caused by certain medical problems.
Before Using This Medicine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For diphenidol, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to diphenidol or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
There is no specific information comparing use of diphenidol for dizziness in children with use in other age groups. Also, there is no specific information about the use of diphenidol for nausea and vomiting in children who weigh less than 22.8 kilograms (50 pounds).
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of diphenidol in the elderly with use in other age groups.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of diphenidol. Make sure you tell your doctor if you have any other medical problems, especially:
- Enlarged prostate or
- Glaucoma or
- Intestinal blockage or
- Low blood pressure or
- Stomach ulcer—Diphenidol may make these conditions worse.
- Kidney disease or
- Urinary tract blockage—Higher blood levels of diphenidol may occur, increasing the chance of side effects.
Proper Use of This Medicine
If you are taking diphenidol to prevent nausea and vomiting, it may be taken with food or a glass of water or milk to lessen stomach irritation, unless otherwise directed by your doctor. However, if you are already suffering from nausea and vomiting, it is best to keep the stomach empty, and diphenidol should be taken only with a small amount of water.
Take diphenidol only as directed. Do not take more of it and do not take it more often than directed by your doctor. To do so may increase the chance of side effects.
The dose of diphenidol will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of diphenidol. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (tablets):
- Adults: 25 to 50 milligrams (mg) every four hours as needed.
- Children: The dose is based on body weight and must be determined by the doctor.
If you miss a dose of diphenidol, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions While Using This Medicine
Diphenidol will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for hay fever, other allergies, or colds; sedatives, tranquilizers, or sleeping medicine; prescription pain medicine or narcotics; barbiturates; medicine for seizures; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of the above while you are using diphenidol.
Diphenidol may cause some people to have blurred vision or to become dizzy, drowsy, or less alert than they are normally. Make sure you know how you react to diphenidol before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert or able to see well.
This Medicine Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:
- hallucinations (seeing, hearing, or feeling things that are not there)
Symptoms of overdose
- Drowsiness (severe)
- shortness of breath or trouble with breathing
- unusual tiredness or weakness (severe)
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Blurred vision
- dry mouth
- nervousness, restlessness, or trouble with sleeping
- skin rash
- stomach upset or pain
- unusual tiredness or weakness
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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