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Invega Sustenna and Fatigue: What Users Say

Fatigue: mentioned by 9 users (4.7%)

Based on user experiences from 192 Invega Sustenna reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

weight gain 33.3%
depression 21.9%
sexual dysfunction 15.6%
hallucinations 12.0%
tiredness 9.4%
anxiety 8.9%
memory loss 6.8%
insomnia 6.3%
dizziness 4.7%
fatigue 4.7%

Reviews for Invega Sustenna

Commonly mentioned side effects
  • Fra...
  • Taken for 6 months to 1 year
  • December 14, 2018

For Schizoaffective Disorder "Do not take this medicine. So far, I have lost all my ambition, energy, personality, and my emotions. I am tired all the time and have random muscle spasms all through my body. It makes it really hard to feel things, I feel like I have to try to feel things. It's really weird. I have been taking the injection for six months now, and I'm a complete zombie. I have no social life, sex drive, or imagination. This medicine destroys the human body, it is poison and needs to be discontinued. I'd much rather hear voices and hallucinate than be on this medication."

1 / 10
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  • Yes...
  • March 11, 2019

For Schizophrenia "This medicine is horrible. Every time I take it, I am unable to work out. I can't even run a mile, I am so weak. I get restless leg syndrome, fatigue, weight gain, and blurred vision. I'm done taking medicine, sick of it."

1 / 10
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53 Report
  • Dip...
  • June 13, 2018

For Schizoaffective Disorder "I was admitted to the hospital for depression. But they gave me the Invega Sustenna 234 injection. My mouth became totally numb for 2 months. I could not swallow any solid food. I could not properly talk for 2 full months. Only lived on liquids. Had no energy in my body at all. Only slept and lied down 24 hours. Had no energy even to open the medication bottle. Really felt horrible inside. Felt muscle locks. Literally lived like a zombie for 2 months. Had extreme anxiety and suicidal thoughts. My teeth have moved permanently. Can’t bite or chew the same way anymore. 4 months later, I still don’t feel normal. I feel this injection has ruined my life permanently. I feel there is something wrong with my body organs. I can’t make anybody understand that I just don’t feel normal anymore. I feel chills in my body. Hard to get up in the morning for work. Feel extremely fatigue and depressed. I actually have more issues than what I just described."

1 / 10
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Frequently asked questions

  • cji...
  • Taken for less than 1 month
  • May 26, 2019

For Schizoaffective Disorder "I was misdiagnosed with schizoaffective disorder and received the booster and initial shot of this medication. I had terrible side effects, including 60 lb of weight gain. I also slept a lot and had little energy. After 6 months of discontinuation, I finally started losing weight and returned to my normal weight. I had to take a gap year during this time, and this drug wasted a year of my life."

1 / 10
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34 Report
  • Anonymous
  • Taken for 1 to 2 years
  • May 10, 2022

For Schizophrenia "I have been on Invega Sustenna for almost 2 years for schizophrenia. I’ve stuck with Invega Sustenna for so long because it is the second-best option in terms of side effects (definitely not saying that it is a good drug). I have erectile dysfunction, insomnia, feeling of mental pain and loneliness, extreme fatigue, lack of motivation, worsened vision, and short-term memory loss from this medication (all of the medications, in fact). I’m showering about once a month, brushing teeth about twice a week, and never exercising because I physically can’t do better on this medication. I used to shower and brush teeth daily in addition to having a six-pack (abs). This medication is another antipsychotic that was marketed without care for how the patients feel physically or mentally while taking it. In short, current antipsychotics do work, but the side effects are unbearable."

1 / 10
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17 Report

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  • Rea...
  • Taken for 1 to 6 months
  • December 3, 2019

For Schizophrenia "Let’s start off by saying it causes bloating. I hate the feeling. I have been dieting and exercising but no results after eating. I have no sex drive, tiredness, no emotion, and lack of energy. I also don’t want to leave the house. This shot has worked for my voices, but the side effects are worse. Hopefully getting off of it soon."

1 / 10
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23 Report
  • Jen...
  • Taken for 1 to 2 years
  • January 12, 2021

For Schizophrenia "My husband is borderline schizophrenic, and he is given the injection once a month. He has been given the needle for 18 months. During this time, he is always asleep, no energy, no interest in life, very slow walking, and just can’t do anything. This is not living, just existing. Is there an alternative to this drug? So fed up with it all."

4 / 10
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19 Report

More FAQ

  • tk9...
  • Taken for 2 to 5 years
  • May 14, 2023

For Schizophrenia "This medication has turned me into a couch potato. Most of my life, I have been a fit and physically active person, but since I have been given this medication, I have been struggling to get the energy to do anything. It took away my motivation in life, and I have become numb emotionally. It does help with my symptoms a bit, but there has to be better medication out there than this."

1 / 10
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10 Report
  • Rob...
  • July 13, 2021

For Schizophrenia "Invega Sustenna was difficult at first. I felt very tired and would get headaches. I believe this was my body adjusting. After a few months, and now on the drug for a few years, I have had a great experience. I still have symptoms once in a while, but not as bad. With the education I was given before taking the drug for my first time, I am now well aware of what a 'symptom' is. I am prepared. The drug Invega Sustenna has only improved my thoughts, speech, and dialect. As I would hear voices, preventing me from speaking clearly, Invega Sustenna has given me the ability to articulate my sentences. When I am ready, I will take either oral tablets or a 3-month injection. I think this will only help my limitations that I keep private. I no longer have headaches. I am no longer fatigued. I am in a good position, and I am proud of the person I am becoming."

10 / 10
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14 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.