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Oxymetazoline nasal User Reviews & Ratings (Page 2)

Brand names: Afrin, Zicam Extreme Congestion Relief, Vicks Sinex 12-Hour Decongestant Nasal Spray, Afrin NoDrip Severe Congestion, Zicam Sinus Relief, Afrin Original, Mucinex Sinus-Max Full Force, Afrin Sinus, Afrin NoDrip Extra Moisturizing, Afrin NoDrip Original, Afrin NoDrip Sinus, 12 Hour Nasal Decongestant Spray, Vicks Sinex Severe Nasal Spray, Afrin Allergy Sinus Nasal Spray, Vicks Sinex Moisturizing 12-Hour Decongestant UltraFine Mist, Afrin Severe Congestion, Rhinase D Moisturizing Nasal Decongestant, Nostrilla, Four-Way Nasal Spray, Vicks Sinex 12-Hour Decongestant UltraFine Mist, Mucinex Sinus-Max Moisture Smart, Dristan 12 Hour Nasal Spray, Vicks QlearQuil 12 Hour Nasal Decongestant Moisturizing Spray, Nostrilla 12 Hour, Todays Health Nasal Relief Extra Moisturizing, Afrin NoDrip Allergy Sinus, Mucinex Sinus-Max Clear & Cool Giltuss Severe Sinus Allerest 12 Hour Nasal Spray Duramist Plus CVS Health Sinus Relief Genasal 12 Hour Nasal …show all brand names

Oxymetazoline nasal has an average rating of 4.7 out of 10 from a total of 228 reviews on Drugs.com. 37% of reviewers reported a positive experience, while 54% reported a negative experience.

Reviews for Oxymetazoline nasal

Commonly mentioned side effects
  • Kiy...
  • September 6, 2018

Oxymetazoline nasal for Nasal Congestion "My doctor recommended this product. I tried for hours to get the cap off. Yes, I understand the directions and have plenty of experience removing childproof caps. I pressed and turned and got only clicks. I pressed soft, hard, and in between. I pressed hard enough to collapse the neck of the bottle and turned so hard it distorted the bottle. I looked on the internet and found hundreds of postings about Afrin with these adult-proof caps, going back 3 years. I finally went to CVS and bought the CVS brand of the same medication in a bottle that opened normally. I am returning my bottle of Afrin to the store where I bought it. I have no opinion about the Afrin brand as it is inaccessible."

1 / 10
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11 Report
  • yar...
  • Taken for less than 1 month
  • June 6, 2020

Oxymetazoline nasal for Nasal Congestion "Have used Afrin in the past, and it has always worked great. Completely cleared up congestion in 10 minutes. The problem is the rebound congestion 12 hours later. This time, I've used it for 3 straight days, and the rebound is bad. Will try something different next time."

6 / 10
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8 Report
  • Sli...
  • Taken for 2 to 5 years
  • May 6, 2018

Oxymetazoline nasal for Nasal Congestion "So I had a cold and my nose was congested, I bought Afrin. While it helped me breathe, it also caused me a terrible rebound congestion (like a physical addiction). After the cold was over, I still needed to use Afrin in order to breathe. It also somehow caused me to have more nasal discharge. I had to ask someone to send me different nose spray/drops from Russia. I used that and there was less nasal discharge, and I didn’t have to use it as much. Unfortunately, I ran out of it two days ago and had to buy Afrin again, and AGAIN my nose is soooo runny and so congested after an hour of using Afrin. I have contacted Afrin, the customer service is extremely rude. I mean, this honestly ruined my life. Imagine needing to use Afrin in order to breathe? Don’t get it!"

1 / 10
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10 Report

Frequently asked questions

  • Bob...
  • April 16, 2019

Oxymetazoline nasal for Nasal Congestion "3 of the last 5 containers of Afrin I purchased would not open! This over a one-year period, so Afrin is refusing to rectify the packaging defect. I will never purchase Afrin. How stupid can a company be?"

1 / 10
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9 Report
  • Jim...
  • Taken for 5 to 10 years
  • November 1, 2019

Oxymetazoline nasal for Nasal Congestion "First of all, I've been using Afrin for 7 years. It works, yes, and I have the most severe sinus pressure you can think of. I'm told that I should get off of it, but there's no other product that opens my sinuses like Afrin. It definitely doesn't last for 12 hours, though. I've always had abnormally strong hands because I lift granite and bodybuild, so the cap has never given me problems. All I can say to everyone else is, strengthen your hands."

7 / 10
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17 Report

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  • jGa...
  • Taken for less than 1 month
  • October 8, 2018

Oxymetazoline nasal for Nasal Congestion "Never, never take this medication. I repeat, never. This medication put me in a worse position than I was before. I decided to take this because all of the pills weren’t working, but it does not help. Afrin says to put 2 squirts in each nostril every 10-12 hours. However, when doing that, it creates a horrible burning sensation in your nose and specifically your throat that lasts for hours. If you want to be congested and burning for hours, take this."

1 / 10
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9 Report
  • Ner...
  • Taken for less than 1 month
  • April 2, 2022

Oxymetazoline nasal for Nasal Congestion "PROS: It cleared up my nasal congestion after 5 days of not being able to breathe normally, and that was HEAVEN. CONS: It made my entire body tremor, my hands and feet sweat, and my heart rate sit at 130+. When awoken from my sleep with these symptoms, it felt very counterproductive, seeing as I couldn’t fall back asleep feeling that nervous and shaky. I guess, luckily, I could breathe though. I do not have high blood pressure or any other diagnosed heart condition. Maybe I’ve just got a sensitive autonomic system that did not like that 'adrenaline dump' right before bed. Afrin works as a vasoconstrictor, and that can come with these above-listed side effects. Lesson learned."

6 / 10
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5 Report
  • Anonymous
  • Taken for less than 1 month
  • January 12, 2025

Oxymetazoline nasal for Nasal Congestion "I took this spray simply to test it out before using it on my child, who has a sinus infection, and I’m very glad I did because I'm experiencing side effects. The bottle says a max of 3 sprays in each nostril, so that's what I dosed myself. After about 30 mins, I was bragging about how great it was, I've never used anything that cleared my nose so well. But within an hour, I had a headache, felt sleepy, and my sinus cavity was extremely dry and so cold when inhaling. I couldn’t fall asleep because of how dried out and cold my nose felt. Then I decided to get up and drink some water and realized that my entire body was cold, I had tremors and felt faint. After a hot shower, I feel better aside from the dry sinuses. But that was scary! I certainly won't ever take it at that dosage again, maybe not ever. Should say 1 spray in each nostril and absolutely no more!"

5 / 10
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1 Report
  • Chi...
  • Taken for less than 1 month
  • June 12, 2018

Oxymetazoline nasal for Nasal Congestion "Be careful when you use it. I tried using the product right before sleeping to breathe easier at night, and it caused me terrible insomnia both nights I used it. It also caused an increased discharge out of my sinuses. I guess it might have been a good experience if I used it for daytime."

3 / 10
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8 Report
  • Cli...
  • January 1, 2023

Oxymetazoline nasal for Nasal Congestion "I have to say, this is a lifesaver! I have NEVER had anything CLEAR my nasal congestion like this! Just amazing. It does seem to dry out the nasal passages in the aftereffect. But it does its job. Just wondering if it might affect the sense of smell. Not sure."

9 / 10
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3 Report
  • Son...
  • Taken for 10 years or more
  • January 22, 2024

Oxymetazoline nasal for Nasal Congestion "For those that have issues with the cap, try the generic version. I have used it for years off-label to help me with my sleep apnea since I can't use a CPAP. I only use it once a night before bedtime, and that, along with two pillows, works like a charm. I do have a bit of congestion once it wears off, but a small price to pay for the ability to sleep safely without apnea attacks. And yes, my physicians have been aware of this."

10 / 10
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2 Report
  • Sho...
  • Taken for less than 1 month
  • January 26, 2015

Oxymetazoline nasal for Nasal Congestion "Worked very well, however, heed the warnings on the label. This product, and I assume all with oxymetazoline, caused me shortness of breath, anxiety attacks, rapid heartbeat, and irregular rhythm. After 2 days, my congestion worsened, but was still relieved via Afrin, however, my concern for the side effects and label warning led me to search for other products that would be able to be used more regularly and without causing said side effects."

5 / 10
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9 Report
  • Com...
  • Taken for less than 1 month
  • February 13, 2019

Oxymetazoline nasal for Nasal Congestion "Afrin really needs to change the caps on their nasal spray. I am in a conference room with at least a dozen people, and no one could get this bottle open. We tried everything recommended, and all we get is that dreadful click. Finally, after over a half hour, I finally managed to get it open. I don't know what did it, but it is fine now. Terrible design and beyond frustrating. I should have videoed the whole process so that people could laugh at us trying to open this stupid bottle."

1 / 10
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7 Report
  • Bob...
  • March 30, 2017

Oxymetazoline nasal for Nasal Congestion "Picture this. You have a new bottle of Afrin in the medicine cabinet. It's 2:00 AM, and you have a stuffy nose. You wake up and go open the Afrin package to find that it is VERY tightly sealed. So, you use some nearby scissors to cut the tape, and instead, you cut yourself. After a few minutes and some blood on your hands, you manage to get the tape off only to find a complex system for the nozzle of the bottle. Still half asleep, you try and get it to work but fail. You miss the old Vicks spray that had a very simple nozzle, throw away the Afrin, and then vow to yourself to remember the name 'Afrin' so that you never buy the product again. You wonder if a lawyer was responsible for human factors design for Afrin, then try to go back to sleep."

1 / 10
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15 Report
  • Lou...
  • May 1, 2020

Oxymetazoline nasal for Nasal Congestion "In my experience, Afrin or similar off-brand nasal sprays smell like mildew after temperature changing in the bottle. Getting warm and cold, warm and cold, mostly from being in your pocket or in your vehicle. It’s essentially stagnant water that grows bacteria, hence, the mildew smell."

2 / 10
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6 Report
  • Anonymous
  • Taken for less than 1 month
  • October 2, 2022

Oxymetazoline nasal for Nasal Congestion "Allow me to add my voice to the choir who is absolutely maddened by the most idiotic, pointlessly difficult packaging I've ever used. I mean... I couldn't even get the packaging open. Afrin, get your head out of the clouds and actually use packaging that wasn't created by a drunk monkey. Then maybe I'll give you an honest assessment of your product."

1 / 10
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3 Report
  • Mel...
  • August 19, 2009

For Nasal Congestion "I tried this product as a result of a bad day of allergies. It worked as advertised, clearing out my sinuses effectively. However, I did not read the directions thoroughly and used it for 3 days. After I stopped, I suffered the rebound congestion, and it was horrible. I nearly gave in to the temptation to use it again, especially since I couldn't sleep with the congestion. Luckily, I found a simple alternative-Breathe Right strips. They hold the sinuses open nicely, allowing me to sleep without turning to Afrin again. Hopefully, the condition will go away."

2 / 10
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11 Report
  • VUa...
  • January 14, 2017

Oxymetazoline nasal for Nasal Congestion "I've used this product for about 15 years, as I have chronic nasal congestion at night. I would have given it a 9 until the new bottle design, which is so horrible I have to give it a 2. I love your product. It would be nice if I could still use it. The cap is way too hard to wrestle off for people who don't have great hand dexterity, and that whole 'line up the tiny white plastic groove with the other tiny white plastic groove' thing is awful. I need to be able to use it in the dark without waking up my spouse. I will switch to another brand if I must."

2 / 10
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7 Report
  • kim...
  • Taken for 2 to 5 years
  • September 30, 2015

Oxymetazoline nasal for Nasal Congestion "Afrin works very well, however, the last 3 or 4 bottles of the spray that I purchased over a year ago started smelling like mildew after a month or so. What is causing this? The expiration date on the container is 2 years away."

8 / 10
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10 Report
  • DHa...
  • Taken for less than 1 month
  • June 16, 2019

Oxymetazoline nasal for Nasal Congestion "I used the 12-hour spray twice over the past 48 hours, and now my nasal passages are completely closed. The pharmacist recommended I take the two decongestant pills; however, not change, and I'm fearing this may require medical attention."

1 / 10
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5 Report
  • Cam...
  • December 31, 2016

Oxymetazoline nasal for Nasal Congestion "What have they done?! They used a very cheap manufactured plastic bottle which can't be opened and used until drilling a hole into it, which leads to wasting half the liquid. Secondly, its use makes your congestion worse, completely blocked after its temporary effect is gone. You end up having no choice but to become addicted to its use. Never recommend it to anyone."

1 / 10
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7 Report
  • Bea...
  • October 29, 2016

Oxymetazoline nasal for Nasal Congestion "I will never buy this product again. I could not figure out how to get the ridiculously designed pump to work. Most nasal sprays have a simple screw cap. Not this one. Threw it in the garbage. Worst waste of money in a long time."

1 / 10
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8 Report
  • Not...
  • Taken for 2 to 5 years
  • August 25, 2016

Oxymetazoline nasal for Nasal Congestion "This childproof cap is not operable. I followed your instructions and wound up cutting the damn cap off. The good news for you is a child won't ingest your product, and you won't get sued. The bad news is a pissed-off adult might cut their hand with a knife and switch products. Good job product safety!!!"

8 / 10
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9 Report
  • PCM...
  • Taken for less than 1 month
  • October 19, 2018

Oxymetazoline nasal for Nasal Congestion "Product may be great, but it's worthless if you can't open the bottle to use it. Horrific container design. Based on countless reviews and videos, this should have prompted product changes by now. Generic brand works just as well and doesn't waste valuable life trying to open the cap."

1 / 10
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5 Report
  • Mar...
  • January 18, 2017

Oxymetazoline nasal for Nasal Congestion "Medication works great for nasal congestion. Now, trying to take off the lid is a different story, I almost returned it. After 3 minutes, a fellow coworker finally got the lid off. I understand childproofing, but this is ridiculous!"

3 / 10
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6 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.