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Nasal antihistamines and decongestants

What are Nasal antihistamines and decongestants?

Nasal antihistamines and decongestants are products that contain either an antihistamine or a decongestant, in a device suitable for nasal use.

Antihistamines block the action of histamine which is released by cells in response to allergens. Nasal antihistamines relieve symptoms such as sneezing, a runny nose, or postnasal drip.

Nasal decongestants constrict dilated blood vessels within the nose, reducing swelling which allows air to flow more freely, relieving symptoms of congestion.

List of Nasal antihistamines and decongestants:

View by  Brand | Generic
Drug Name Avg. Rating Reviews
Dymista (Pro)
Generic name: azelastine / fluticasone
5.8
133 reviews
Afrin
Generic name: oxymetazoline
3.2
116 reviews
Vicks Sinex Nasal Spray (old formulation)
Generic name: phenylephrine
6.2
24 reviews
Astelin (Pro)
Generic name: azelastine
9.1
21 reviews
Astepro (Pro)
Generic name: azelastine
8.7
20 reviews
Nostrilla
Generic name: oxymetazoline
6.9
14 reviews
Privine
Generic name: naphazoline
10
12 reviews
Patanase (Pro)
Generic name: olopatadine
7.5
11 reviews
Vicks Sinex 12-Hour Decongestant Nasal Spray
Generic name: oxymetazoline
6.0
6 reviews
NasalCrom
Generic name: cromolyn
7.5
4 reviews
Afrin Original
Generic name: oxymetazoline
5.2
4 reviews
Zicam Extreme Congestion Relief
Generic name: oxymetazoline
9.5
3 reviews
Atrovent Nasal (Pro)
Generic name: ipratropium
10
3 reviews
Afrin NoDrip Original
Generic name: oxymetazoline
5.5
3 reviews
Neo-Synephrine Nasal
Generic name: phenylephrine
10
2 reviews
Afrin Sinus
Generic name: oxymetazoline
8.0
2 reviews
Afrin NoDrip Extra Moisturizing
Generic name: oxymetazoline
6.7
2 reviews
Afrin 4 Hour Extra Moisturizing
Generic name: phenylephrine
9.0
2 reviews
12 Hour Nasal Decongestant Spray
Generic name: oxymetazoline
3.5
2 reviews
Zicam Sinus Relief
Generic name: oxymetazoline
10
1 review
Todays Health Nasal Relief Extra Moisturizing
Generic name: oxymetazoline
10
1 review
Mucinex Sinus-Max Full Force (Pro)
Generic name: oxymetazoline
10
1 review
Afrin NoDrip Sinus
Generic name: oxymetazoline
5.0
1 review
12 Hour Nasal
Generic name: oxymetazoline
1 review
Vicks Sinex Severe Nasal Spray
Generic name: oxymetazoline
No reviews
Vicks Sinex Moisturizing 12-Hour Decongestant UltraFine Mist
Generic name: oxymetazoline
No reviews
Vicks QlearQuil 12 Hour Nasal Decongestant Moisturizing Spray
Generic name: oxymetazoline
No reviews
Tyzine (Pro)
Generic name: tetrahydrozoline
No reviews
Triaminic Decongestant Spray Nasal & Sinus Congestion
Generic name: xylometazoline
No reviews
Sudafed OM Sinus Cold
Generic name: oxymetazoline
No reviews
Sinarest Nasal
Generic name: oxymetazoline
No reviews
Rhinall
Generic name: phenylephrine
No reviews
NRS Nasal
Generic name: oxymetazoline
No reviews
Neo-Synephrine 12 Hour
Generic name: oxymetazoline
No reviews
Nasal Four
Generic name: phenylephrine
No reviews
Mucinex Sinus-Max Moisture Smart
Generic name: oxymetazoline
No reviews
Mucinex Sinus-Max Clear & Cool
Generic name: oxymetazoline
No reviews
Little Noses Decongestant
Generic name: phenylephrine
No reviews
Genasal
Generic name: oxymetazoline
No reviews
Four-Way Nasal Spray
Generic name: oxymetazoline
No reviews
Duration
Generic name: oxymetazoline
No reviews
Duramist Plus
Generic name: oxymetazoline
No reviews
Dristan 12 Hour Nasal Spray
Generic name: oxymetazoline
No reviews
Benzedrex
Generic name: propylhexedrine
No reviews
Allerest 12 Hour Nasal Spray
Generic name: oxymetazoline
10
No reviews
Afrin Severe Congestion
Generic name: oxymetazoline
10
No reviews
4-Way Menthol
Generic name: phenylephrine
10
No reviews
4 Way Fast Acting Nasal Spray
Generic name: phenylephrine
No reviews
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

See Also

Medical conditions associated with nasal antihistamines and decongestants:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.