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Olopatadine (nasal)

Generic name: olopatadine (nasal) [ OH-loe-PA-ta-deen ]
Brand name: Patanase
Dosage form: nasal spray (665 mcg/inh)
Drug class: Nasal antihistamines and decongestants

Medically reviewed by on Oct 7, 2021. Written by Cerner Multum.

What is olopatadine nasal?

Olopatadine nasal (for the nose) is used to treat seasonal allergy symptoms such as congestion, sneezing, and runny nose.

Olopatadine nasal is for use in adults and children at least 6 years old.

Olopatadine nasal may also be used for purposes not listed in this medication guide.


Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use olopatadine if you are allergic to olopatadine.

Tell your doctor if you have other conditions that affect the inside of your nose.

Tell your doctor if you are pregnant or breastfeeding.

Not approved for use by anyone younger than 6 years old.

How should I use olopatadine nasal?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Before your first use, shake the nasal spray well and prime it with 5 sprays into the air, until a fine mist appears. Spray away from your face. Prime again with 2 sprays whenever the medicine has not been used in longer than 7 days.

Gently blow your nose before using the nasal spray.

Carefully follow all Instructions for Use provided with this medicine.

Call your doctor if your symptoms do not improve, or if they get worse.

Store at room temperature away from moisture and heat.

Throw away the bottle after 240 sprays have been used, even if there is still medicine left inside. If used daily, one bottle contains enough medicine for 30 days for an adult dose or 60 days for a child's dose.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling agitated or restless and then drowsy.

What should I avoid while taking olopatadine nasal?

Avoid driving or hazardous activity until you know how olopatadine will affect you. Your reactions could be impaired.

Drinking alcohol with this medicine can cause side effects.

Avoid getting this medication in your eyes.

Olopatadine nasal side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Olopatadine may cause serious side effects. Stop using olopatadine and call your doctor at once if you have:

  • nosebleed;

  • painful sores inside your nose;

  • fever; or

  • pain or burning when you urinate.

Common side effects of olopatadine may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Olopatadine dosing information

Usual Adult Dose for Allergic Rhinitis:

2 sprays in each nostril twice a day

Use: For the relief of symptoms of seasonal allergic rhinitis

Usual Pediatric Dose for Allergic Rhinitis:

6 to 11 years: 1 spray in each nostril twice a day

12 years or older: 2 sprays in each nostril twice a day

Use: For the relief of symptoms of seasonal allergic rhinitis

What other drugs will affect olopatadine nasal?

Using olopatadine with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect olopatadine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.